c-Fms-IN-8

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

c-Fms-IN-8 

c-Fms-IN-8 (compound 4a)是 CSF-1R 的 2 型抑制剂,其IC50 值为9.1 nM。

c-Fms-IN-8

c-Fms-IN-8 Chemical Structure

CAS No. : 1255303-58-2

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生物活性

c-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM[1].

IC50 & Target

IC50: 9.1 nM (CSF-1R)[1].

分子量

462.54

Formula

C27H30N2O5

CAS 号

1255303-58-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Ikegashira K, et al. Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models. Bioorg Med Chem Lett. 2019 Jan 1;29(1):115-118.

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