MAK683 hydrochloride

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

MAK683 hydrochloride 

MAK683 hydrochloride 是胚胎外胚层发育 (EED) 抑制剂，来自专利US20160176882 A1，化合物实例 2；在EED Alphascreen，LC-MS 和 ELISA 试验中的 IC50 值分别为 59，89，26 nM。

MAK683 hydrochloride

MAK683 hydrochloride Chemical Structure

CAS No. : 2170606-94-5

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MAK683 hydrochloride 的其他形式现货产品:

MAK683

生物活性

MAK683 hydrochloride is an embryonic ectoderm development (EED) inhibitor extracted from patent US20160176882 A1, compound example 2. MAK683 exhibits IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay[1][2].

分子量

412.85

Formula

C20H18ClFN6O
CAS 号

2170606-94-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Chan, Ho Man, et al. TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF. US20160176882 A1.

    [2]. Huang D, et al. Binding Modes of Small-Molecule Inhibitors to the EED Pocket of PRC2. Chemphyschem. 2020 Feb 4;21(3):263-271.

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