上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
(E/Z)-BIO-acetoxime (Synonyms: GSK-3 Inhibitor X)
(E/Z)-BIO-acetoxime (GSK-3 Inhibitor X) 是一种有效的选择性 GSK-3α/β 抑制剂，IC50 为 10 nM。(E/Z)-BIO-acetoxime 对 GSK-3α/β 具有超过 CDK5/p25，CDK2/cyclin A 和 CDK1/cyclin B (IC50=2.4, 4.3, 63 μM) 200 倍的选择性。
(E/Z)-BIO-acetoxime Chemical Structure
CAS No. : 740841-15-0
| 规格 | 是否有货 | ||
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| 5 mg | 询价 | ||
| 10 mg | 询价 |
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| 生物活性 |
(E/Z)-BIO-acetoxime (GSK-3 Inhibitor X) is a potent and selective GSK-3α/β inhibitor, with an IC50 of 10 nM. (E/Z)-BIO-acetoxime shows more than 200-flod selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B (IC50=2.4, 4.3, 63 μM)[1]. |
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| IC50 & Target[1] |
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| 体外研究 (In Vitro) |
E/Z)-BIO-acetoxime (compound 13) shows more than 200-flod selectivity for GSK-3α/β over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B, with IC50s of 0.01, 2.4, 4.3 and 63 μM, respectively[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
398.21 |
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| Formula |
C18H12BrN3O3 |
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| CAS 号 |
740841-15-0 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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