(+)-(3R,8S)-Falcarindiol(Synonyms: (3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol)

发表于由

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(+)-(3R,8S)-Falcarindiol (Synonyms: (3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol) 纯度: 99.88%

(+)-(3R,8S)-Falcarindiol 是从胡萝卜中得到的聚乙炔，具有抗分歧杆菌 (antimycobacterial) 作用，对 Mycobacterium tuberculosis H37Ra 的最低抑制浓度 MIC 和 IC50 值分别为 24 μM 和 6 μM。具有抗肿瘤和抗炎作用。

(+)-(3R,8S)-Falcarindiol(Synonyms: (3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol)

(+)-(3R,8S)-Falcarindiol Chemical Structure

CAS No. : 225110-25-8

规格 价格 是否有货 数量
1 mg ￥800 In-stock
5 mg ￥2800 In-stock
10 mg ￥4400 In-stock
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(+)-(3R,8S)-Falcarindiol 相关产品

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生物活性

(+)-(3R,8S)-Falcarindiol is a polyacetylene found in carrots, has antimycobacterial activity, with an IC50 of 6 μM and MIC of 24 μM against Mycobacterium tuberculosis H37Ra[1][2]. Antineoplastic and anti-inflammatory activity[2].

IC50 & Target

IC50: 6 μM (Mycobacterium tuberculosis H37Ra)[1]
分子量

260.37

Formula

C17H24O2
CAS 号

225110-25-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. O’Neill T, et al. The Canadian medicinal plant Heracleum maximum contains antimycobacterial diynes and furanocoumarins. J Ethnopharmacol. 2013 May 2;147(1):232-7.

    [2]. Kobaek-Larsen M, et al. Effect of the dietary polyacetylenes falcarinol and falcarindiol on the gut microbiota composition in a rat model of colorectal cancer. BMC Res Notes. 2018 Jun 27;11(1):411.

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