Batatasin III(Synonyms: 山药素Ⅲ)

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Batatasin III (Synonyms: 山药素Ⅲ) 纯度: 99.70%

Batatasin III 是一种芪类化合物,通过抑制上皮间质转化 (EMT) 和FAK-AKT 信号来抑制癌症迁移和侵袭。Batatasin III 具有抗癌活性。

Batatasin III(Synonyms: 山药素Ⅲ)

Batatasin III Chemical Structure

CAS No. : 56684-87-8

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生物活性

Batatasin III, a stilbenoid, inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition (EMT) and FAK-AKT signals. Batatasin III has anti-cancer activities[1].

IC50 & Target[1]

Akt

 

体外研究
(In Vitro)

Batatasin III (25-100 μM; 48 h) exhibits anti-proliferative activity in H460 cells. Batatasin III at concentrations lower than 100 μM has no cytotoxic effects[1].
Batatasin III significantly suppresses EMT indicated by the decrease of N-cadherin and Vimentin, and up-regulation of E-cadherin[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

244.29

Formula

C15H16O3

CAS 号

56684-87-8

中文名称

山药素Ⅲ

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

参考文献
  • [1]. Tatchakorn Pinkhien, et al. Batatasin III Inhibits Migration of Human Lung Cancer Cells by Suppressing Epithelial to Mesenchymal Transition and FAK-AKT Signals. Anticancer Res. 2017 Nov;37(11):6281-6289.

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