PTD-p65-P1 Peptide TFA

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PTD-p65-P1 Peptide TFA  纯度: 96.33%

PTD-p65-P1 Peptide TFA 是一种核转录因子 NF-kappaB 抑制剂,由一个 antennapedia 衍生的膜转运肽序列 (PTD) 连接 p65-P1 构成, 选择性地抑制由各种刺激诱导的 NF-kappaB 活性。

PTD-p65-P1 Peptide TFA

PTD-p65-P1 Peptide TFA Chemical Structure

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1 mg ¥1800 In-stock
5 mg ¥5500 In-stock
10 mg ¥9500 In-stock
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PTD-p65-P1 Peptide TFA 相关产品

相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

PTD-p65-P1 Peptide TFA is a nuclear transcription factor NF-kappaB inhibitor, composed of a membrane-translocating peptide sequence generated from antennapedia (PTD) conjugated with p65-P1, which selectively inhibits activation induced by various inflammatory stimuli[1].

IC50 & Target

NF-kappaB[1]

分子量

3943.52

Formula

C170H276F3N57O46S

Sequence

Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Gln-Leu-Arg-Arg-Pro-Ser-Asp-Arg-Glu-Leu-Ser-Glu

Sequence Shortening

DRQIKIWFQNRRMKWKKQLRRPSDRELSE

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

参考文献
  • [1]. Takada Y, et al. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis. J Biol Chem. 2004 Apr 9;279(15):15096-104.

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