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Bromelain (Synonyms: 菠萝蛋白酶)
Bromelain 是一种源自菠萝茎的抗炎药，其通过下调血浆激肽原，抑制前列腺素 E2 表达，降解晚期糖基化终产物受体，调节血管生成生物标志物以及在 COX 途径上游发生抗氧化作用而发挥作用。Bromelain 具有多种纤维蛋白溶解，抗水肿，抗血栓形成和抗炎活性。Bromelain 还具有一些抗癌活性，并促进凋亡细胞死亡。
Bromelain Chemical Structure
CAS No. : 9001-00-7
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 100 mg | ￥500 | In-stock | |
| 200 mg | 询价 | ||
| 500 mg | 询价 |
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Bromelain 相关产品
•相关化合物库:
- Drug Repurposing Compound Library Plus
- Clinical Compound Library Plus
- Bioactive Compound Library Plus
| 生物活性 |
Bromelain is an anti-inflammatory drug derived from pineapple stem that acts through down-regulation of plasma kininogen, inhibition of Prostaglandin E2 expression, degradation of advanced glycation end product receptors and regulation of angiogenic biomarkers as well as antioxidant action upstream in the COX-pathway[1]. Bromelain exhibits various fibrinolytic, antiedematous, antithrombotic, and anti-inflammatory activities. Bromelain also possesses some anticancerous activities and promotes apoptotic cell death[2]. |
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| 体内研究 (In Vivo) |
Bromelain (40 mg/kg; intraperitoneal injection; daily; for 7 days; male Sprague-Dawley rats) pretreatment reduces the motor dysfunction in the parkinsonian rat model of parkinson’s disease (PD). 6-OHDA injection resulted in marked motor impairment which is prevented by pretreatment with Bromelain prior to the lesion[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
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| Clinical Trial |
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| CAS 号 |
9001-00-7 |
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| 中文名称 |
菠萝蛋白酶；鳳梨酶；菠萝酶；鳳梨酵素 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 参考文献 |
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