上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
VU0469650
VU0469650 是一种有效的、选择性的、穿透 CNS 的 mGlu1 受体的反向变构调节剂,其 IC50 为99 nM。
VU0469650 Chemical Structure
CAS No. : 1443748-47-7
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100 mg | 询价 | ||
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生物活性 |
VU0469650 is a potent, selective and CNS-penetrated negative allosteric modulator of mGlu1 receptor, with an IC50 of 99 nM[1]. |
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IC50 & Target |
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体内研究 (In Vivo) |
VU0469650 (male Sprague-Dawley rats, 0.2 mg/kg, IV, once) exhibits moderate to high clearance, a moderate volume of distribution, and a half-life of approximately 1 hour[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
364.48 |
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Formula |
C22H28N4O |
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CAS 号 |
1443748-47-7 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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Animal Administration |
Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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参考文献 |
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