TRK-IN-19

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

TRK-IN-19 

TRK-IN-19 (Compound I-10 ) 是一种有效的 TRK 抑制剂 (TRKA IC50 = 1.1 nM, TRKA G595R IC50 = 5.3 nM）。TRK-IN-19 具有研究癌症疾病的潜力。

TRK-IN-19

TRK-IN-19 Chemical Structure

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生物活性

TRK-IN-19 (Compound I-10 ) is a potent inhibitor of TRK (TRKA IC50 = 1.1 nM, TRKAG595R IC50 = 5.3 nM). TRK-IN-19 has the potential for the research of cancer diseases[1].

分子量

411.47

Formula

C22H26FN5O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Sun M, et al. Design, synthesis and biological activity of bicyclic carboxamide derivatives as TRK inhibitors. Bioorg Med Chem. 2020 Dec 1;28(23):115811. doi: 10.1016/j.bmc.2020.115811.

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