PD-1/PD-L1-IN-26

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

PD-1/PD-L1-IN-26 

PD-1/PD-L1-IN-26 (Compound II-14) 是一种有效的 PD-1/PD-L1 抑制剂，具有 IC< sub>50 的 0.0380 μM。PD-1/PD-L1-IN-26 通过促进 CD4+ T 细胞浸润到肿瘤组织中来激活免疫微环境。PD-1/PD-L1-IN-26 具有研究癌症疾病的潜力。

PD-1/PD-L1-IN-26

PD-1/PD-L1-IN-26 Chemical Structure

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生物活性

PD-1/PD-L1-IN-26 (Compound II-14) is a potent inhibitor of PD-1/PD-L1 with an IC50 of 0.0380 μM. PD-1/PD-L1-IN-26 activates the immune microenvironment by promoting the infiltration of CD4+ T cells into tumor tissues. PD-1/PD-L1-IN-26 has the potential for the research of cancer diseases[1].

分子量

752.89

Formula

C43H52N4O8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Fang L, et al. Discovery of 1,3,4-oxadiazole derivatives as potential antitumor agents inhibiting the programmed cell death-1/programmed cell death-ligand 1 interaction. Bioorg Med Chem. 2021 Sep 15;46:116370.

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