上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
KRAS G12C inhibitor 44
KRAS G12C inhibitor 44 (compound 54) 是一种有效且具有口服活性的 KRAS G12C 抑制剂。KRAS G12C inhibitor 44 在 MIA PaCA-2、H358 细胞中显示出抗增殖活性,IC50s 分别为 0.016,0.028 µM。KRAS G12C inhibitor 44 在体内显示出抗肿瘤作用。
KRAS G12C inhibitor 44 Chemical Structure
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100 mg | 询价 | ||
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500 mg | 询价 |
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生物活性 |
KRAS G12C inhibitor 44 (compound 54) is a potent and orally active KRAS G12C inhibitor. KRAS G12C inhibitor 44 shows anti-proliferation activities with IC50s of 0.016, 0.028 µM in MIA PaCA-2, H358 cells, respectively. KRAS G12C inhibitor 44 shows antitumor effects in vivo[1]. |
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IC50 & Target[1] |
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分子量 |
579.11 |
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Formula |
C31H36ClFN6O2 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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