Antitumor photosensitizer-3

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Antitumor photosensitizer-3 

Antitumor photosensitizer-3 (Compound I) 是一种二氢卟酚衍生物。Antitumor photosensitizer-3 在 650 nm 激光照射下诱导肿瘤细胞凋亡和坏死。体内 Antitumor photosensitizer-3 的皮肤光毒性低于阳性参考 m-THPC。

Antitumor photosensitizer-3

Antitumor photosensitizer-3 Chemical Structure

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生物活性

Antitumor photosensitizer-3 (Compound I) is a chlorin derivative. Antitumor photosensitizer-3 induces tumor cells apoptosis and necrosis under 650 nm laser irradiation. Antitumor photosensitizer-3 exhibits lower skin photo-toxicity than positive reference m-THPC in vivo[1].

分子量

730.81

Formula

C48H34N4O4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Gao YH, et al. Synthesis and pharmacological evaluation of chlorin derivatives for photodynamic therapy of cholangiocarcinoma. Eur J Med Chem. 2020 Mar 1;189:112049.

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