ALDH1A3-IN-2

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

ALDH1A3-IN-2 

ALDH1A3-IN-2 (Compound 15) 是一种有效的 ALDH1A3 抑制剂,IC50 为 0.30 μM。醛脱氢酶 (ALDH) 在包括前列腺癌在内的各种肿瘤类型中过度表达。ALDH1A3-IN-2 具有研究癌症疾病的潜力。

ALDH1A3-IN-2

ALDH1A3-IN-2 Chemical Structure

CAS No. : 886502-08-5

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生物活性

ALDH1A3-IN-2 (Compound 15) is a potent inhibitor of ALDH1A3 with an IC50 of 1.29 μM. Aldehyde dehydrogenases (ALDHs) are overexpressed in various tumor types including prostate cancer. ALDH1A3-IN-2 has the potential for the research of cancer diseases[1].

分子量

203.28

Formula

C13H17NO

CAS 号

886502-08-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Ibrahim AIM, et al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848.

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