DNA crosslinker 1 dihydrochloride

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

DNA crosslinker 1 dihydrochloride 

DNA crosslinker 1 (dihydrochloride) 是一种有效的 DNA 小沟结合剂,与 DNA 的结合亲和力 (ΔTm) 为 1.1 °C。DNA crosslinker 1 (dihydrochloride) 可用于抗癌研究。

DNA crosslinker 1 dihydrochloride

DNA crosslinker 1 dihydrochloride Chemical Structure

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生物活性

DNA crosslinker 1 (dihydrochloride) is a potent DNA minor groove binder with DNA binding affinity (ΔTm) of 1.1 °C. DNA crosslinker 1 (dihydrochloride) can be used for researching anticancer[1].

IC50 & Target

DNA minor groove[1]

分子量

401.29

Formula

C15H22Cl2N8O

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Costas-Lago MC, et al. Novel Pyridazin-3(2H)-one-Based Guanidine Derivatives as Potential DNA Minor Groove Binders with Anticancer Activity. ACS Med Chem Lett. 2022;13(3):463-469. Published 2022 Feb 10.

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