COX-2-IN-18

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

COX-2-IN-18 

COX-2-IN-18 (Compound 3) 是一种有效的 COX-2 抑制剂。COX-2-IN-18 与参比药物 Celecoxib (IC 50 = 0.153 μM)。COX-2-IN-18 具有研究癌症疾病的潜力。

COX-2-IN-18

COX-2-IN-18 Chemical Structure

CAS No. : 1038061-96-9

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生物活性

COX-2-IN-18 (Compound 3) is a potent inhibitor of COX-2. COX-2-IN-18 possesses good COX-2 inhibitory activity (IC50 = 0.775 μM) compared to the reference drug, Celecoxib (IC50 = 0.153 μM). COX-2-IN-18 has the potential for the research of cancer diseases[1].

分子量

389.49

Formula

C18H19N3O3S2

CAS 号

1038061-96-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. El-Azab AS, et al. Antitumor activity, multitarget mechanisms, and molecular docking studies of quinazoline derivatives based on a benzenesulfonamide scaffold: Cell cycle analysis. Bioorg Chem. 2020;104:104345.

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