C6 Ceramide(Synonyms: C6-Cer; N-Hexanoylsphingosine)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

C6 Ceramide (Synonyms: C6-Cer; N-Hexanoylsphingosine)

C6-ceramide是一种神经酰胺途径激活剂，对多种癌细胞系具有活性。C6-ceramide 可用作化疗剂的佐剂，以增强抗肿瘤作用。

C6 Ceramide(Synonyms: C6-Cer; N-Hexanoylsphingosine)

C6 Ceramide Chemical Structure

CAS No. : 124753-97-5

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生物活性

C6-ceramide, a ceramide pathway activator, shows activity against a variety of cancer cell lines. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects[1][2].

分子量

397.63

Formula

C24H47NO3
CAS 号

124753-97-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhu Q, et, al. C6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and α-tubulin hyperacetylation both in vitro and in vivo. Cell Death Dis. 2011 Jan 27;2(1):e117.

    [2]. Liu L, et, al. C6-ceramide treatment inhibits the proangiogenic activity of multiple myeloma exosomes via the miR-29b/Akt pathway. J Transl Med. 2020 Aug 3;18(1):298.

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