C6 Ceramide(Synonyms: C6-Cer; N-Hexanoylsphingosine)

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C6 Ceramide (Synonyms: C6-Cer; N-Hexanoylsphingosine)

C6-ceramide是一种神经酰胺途径激活剂,对多种癌细胞系具有活性。C6-ceramide 可用作化疗剂的佐剂,以增强抗肿瘤作用。

C6 Ceramide(Synonyms: C6-Cer;  N-Hexanoylsphingosine)

C6 Ceramide Chemical Structure

CAS No. : 124753-97-5

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生物活性

C6-ceramide, a ceramide pathway activator, shows activity against a variety of cancer cell lines. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects[1][2].

分子量

397.63

Formula

C24H47NO3

CAS 号

124753-97-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Zhu Q, et, al. C6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and α-tubulin hyperacetylation both in vitro and in vivo. Cell Death Dis. 2011 Jan 27;2(1):e117.

    [2]. Liu L, et, al. C6-ceramide treatment inhibits the proangiogenic activity of multiple myeloma exosomes via the miR-29b/Akt pathway. J Transl Med. 2020 Aug 3;18(1):298.

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