多肽定制PAR-4 (1-6)) amide |Protease Activated Receptor-4 (1-6) amide, human 编码 [245443-51-0]

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名称 PAR-4 (1-6)) amide |Protease Activated Receptor-4 (1-6) amide, human
编码 [245443-51-0]
别名 PAR-4 (1-6)) amide |Protease Activated Receptor-4 (1-6) amide, human
纯度 80%,90%,95%,98%,99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列(单字母缩写) GYPGQV-NH2
序列(三字母缩写) H-Gly-Tyr-Pro-Gly-Gln-Val-NH2
基本描述 Protease-activated receptor-4 activating peptide derived from murine PAR-4. This peptide was able to cause rat platelet aggregation with an EC50 value of 40 碌M. Its effect on leucocyte rolling and adherence points at a role of PAR-4 in mediating proinflammatory processes. The family of at least seven transmembrane G protein coupled receptors includes at least four receptor subtypes (PAR1, PAR2, PAR3, PAR4). PAR4 activating peptides, GYPGKF-NH2 and AYPGKG-NH2, produce concentration dependent contractile effects on the muscle.
溶解度
分子量 618.69
化学式 C28H42N8O8
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents PAR-4 (1-6))  amide |Protease Activated Receptor-4 (1-6) amide, human          编码     [245443-51-0]
Figures PAR-4 (1-6))  amide |Protease Activated Receptor-4 (1-6) amide, human          编码     [245443-51-0]
Reference M.D.Hollenberg et al., Can. J. Physiol. Pharmacol., 77, 458 (1999) M.Tognetto et al., Br. J. Pharmacol., 139, 21 (2003) M.D.Hollenberg and S.Houle, Swiss Med. Wkly., 135, 425 (2005)
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