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| 名称 | PAR-1,Protease Activated Receptor-1(1-6)) (mouse, rat) |
| 编码 | [140436-67-5] |
| 别名 | PAR-1,Protease Activated Receptor-1(1-6)) (mouse, rat) |
| 纯度 | 80%，90%，95%，98%，99% |
| 重量 | 1mg,5mg,10mg,50mg,100mg,1g |
| 序列（单字母缩写） | SFFLRN |
| 序列（三字母缩写） | H-Ser-Phe-Phe-Leu-Arg-Asn-OH (trifluoroacetate salt) |
| 基本描述 | This peptide inhibited activation of PAR-2 by trypsin in PAR-2 receptor expressing KNRK cells. Half-maximal inhibition of calcium signaling was observed at about 50 碌M. In contrast, the activation of PAR-2 by SLIGRL-NH2 (PAR-2 (1-6) amide (mouse, rat)) was not inhibited by this peptide. Selective Antagonist for PAR2 Agonist. This peptide blocks trypsin but not SLIGRL-NH2 activation of PAR2 in receptor-expressing KNRK cells. |
| 溶解度 | |
| 分子量 | 782.9 |
| 化学式 | C37H54N10O9 |
| 存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
| 注释 | |
| Documents | ![PAR-1,Protease Activated Receptor-1(1-6)) (mouse, rat) 编码 [140436-67-5]](http://www.fluoroprobe.com/wp-content/uploads/2022/10/20221013_63481d291140d.png) |
| Figures | ![PAR-1,Protease Activated Receptor-1(1-6)) (mouse, rat) 编码 [140436-67-5]](http://www.fluoroprobe.com/wp-content/uploads/2022/10/20221013_63481d2969692.jpg) |
| Reference | Z.Suo et al., J. Biol. Chem., 278, 37681 (2003) P.J.Yu et al., Oncogene, 27, 2594 (2008) F.Bock et al., Proc. Natl. Acad. Sci. USA, 110, 648 (2013) |
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