FTISADTSK

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

FTISADTSK 

FTISADTSK 是一种内源性稳定的曲妥珠单抗信号肽,由 SRM 监测得到。

FTISADTSK

FTISADTSK Chemical Structure

CAS No. : 1431957-73-1

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

FTISADTSK 的其他形式现货产品:

FTISADTSK acetate

生物活性

FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM)[1].

分子量

969.05

Formula

C42H68N10O16

CAS 号

1431957-73-1

Sequence Shortening

FTISADTSK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Bults P, et al. LC-MS/MS-Based Monitoring of In Vivo Protein Biotransformation: Quantitative Determination of Trastuzumab and Its Deamidation Products in Human Plasma. Anal Chem. 2016;88(3):1871-1877.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

FTISADTSK

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

FTISADTSK 

FTISADTSK 是一种内源性稳定的曲妥珠单抗信号肽,由 SRM 监测得到。

FTISADTSK

FTISADTSK Chemical Structure

CAS No. : 1431957-73-1

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

FTISADTSK 的其他形式现货产品:

FTISADTSK acetate

生物活性

FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM)[1].

分子量

969.05

Formula

C42H68N10O16

CAS 号

1431957-73-1

Sequence Shortening

FTISADTSK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Bults P, et al. LC-MS/MS-Based Monitoring of In Vivo Protein Biotransformation: Quantitative Determination of Trastuzumab and Its Deamidation Products in Human Plasma. Anal Chem. 2016;88(3):1871-1877.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

FTISADTSK

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

FTISADTSK 

FTISADTSK 是一种内源性稳定的曲妥珠单抗信号肽,由 SRM 监测得到。

FTISADTSK

FTISADTSK Chemical Structure

CAS No. : 1431957-73-1

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

FTISADTSK 的其他形式现货产品:

FTISADTSK acetate

生物活性

FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM)[1].

分子量

969.05

Formula

C42H68N10O16

CAS 号

1431957-73-1

Sequence Shortening

FTISADTSK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Bults P, et al. LC-MS/MS-Based Monitoring of In Vivo Protein Biotransformation: Quantitative Determination of Trastuzumab and Its Deamidation Products in Human Plasma. Anal Chem. 2016;88(3):1871-1877.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Ivangustin

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Ivangustin 

Ivangustin 是从药用植物 Inula britannica 中分离得到的一种倍半萜。

Ivangustin

Ivangustin Chemical Structure

CAS No. : 14164-59-1

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Ivangustin is a sesquiterpene isolated from the flower heads of the medicinal plant Inula britannica[1].

体外研究
(In Vitro)

Ivangustin is against HeLa, PC-3, Hep-2, HepG2, CHO and HUVEC cells with IC50 of 3.2 μM, 4.5 μM, 3.3 μM, 5.2 μM, 6.4 μM, and 9.2 μM, respectively in a SRB colorimetric assay[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

248.32

Formula

C15H20O3

CAS 号

14164-59-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Jiang-Jiang Tang, et al. Diversity Modification and Structure-Activity Relationships of Two Natural Products 1β-hydroxy Alantolactone and Ivangustin as Potent Cytotoxic Agents.Sci Rep. 2018 Jan 29;8(1):1722.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Ivangustin

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Ivangustin 

Ivangustin 是从药用植物 Inula britannica 中分离得到的一种倍半萜。

Ivangustin

Ivangustin Chemical Structure

CAS No. : 14164-59-1

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Ivangustin is a sesquiterpene isolated from the flower heads of the medicinal plant Inula britannica[1].

体外研究
(In Vitro)

Ivangustin is against HeLa, PC-3, Hep-2, HepG2, CHO and HUVEC cells with IC50 of 3.2 μM, 4.5 μM, 3.3 μM, 5.2 μM, 6.4 μM, and 9.2 μM, respectively in a SRB colorimetric assay[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

248.32

Formula

C15H20O3

CAS 号

14164-59-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Jiang-Jiang Tang, et al. Diversity Modification and Structure-Activity Relationships of Two Natural Products 1β-hydroxy Alantolactone and Ivangustin as Potent Cytotoxic Agents.Sci Rep. 2018 Jan 29;8(1):1722.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Ivangustin

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Ivangustin 

Ivangustin 是从药用植物 Inula britannica 中分离得到的一种倍半萜。

Ivangustin

Ivangustin Chemical Structure

CAS No. : 14164-59-1

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Ivangustin is a sesquiterpene isolated from the flower heads of the medicinal plant Inula britannica[1].

体外研究
(In Vitro)

Ivangustin is against HeLa, PC-3, Hep-2, HepG2, CHO and HUVEC cells with IC50 of 3.2 μM, 4.5 μM, 3.3 μM, 5.2 μM, 6.4 μM, and 9.2 μM, respectively in a SRB colorimetric assay[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

248.32

Formula

C15H20O3

CAS 号

14164-59-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Jiang-Jiang Tang, et al. Diversity Modification and Structure-Activity Relationships of Two Natural Products 1β-hydroxy Alantolactone and Ivangustin as Potent Cytotoxic Agents.Sci Rep. 2018 Jan 29;8(1):1722.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Cathayanon H

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Cathayanon H 

Cathayanon H 是从纸桑树中分离出来。Cathayanon H 对人卵巢癌细胞具有细胞毒性。

Cathayanon H

Cathayanon H Chemical Structure

CAS No. : 1303438-51-8

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Cathayanon H is isolated from the paper mulberry tree. Cathayanon H is cytotoxic against human ovariancarcinoma cells[1].

分子量

424.49

Formula

C25H28O6

CAS 号

1303438-51-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Chin-Feng Chang, et al. Bioactive compounds from the bark of Broussonetia papyrifera after solid fermentation with a white rot fungus Perenniporia tephropora. Journal of Wood Chemistry and Technology, Volume 40, 2020 – Issue 5.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Sappanchalcone

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Sappanchalcone 

Sappanchalcone 从 Caesalpinia sappan L. 中提取的黄酮类化合物,诱导人结肠癌细胞凋亡 (apoptosis)。

Sappanchalcone

Sappanchalcone Chemical Structure

CAS No. : 94344-54-4

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells[1].

体外研究
(In Vitro)

Sappanchalcone has a statistically significant effect on HCT116 cells than on SW480 cells (IC50= 37.33 μM and 54.23 μM, respectively). Sappanchalcone reduces MMP with a significant increase in ROS levels in human colon cancer cells. Sappanchalcone triggered phosphorylation of p53, which is involved in the activation of caspases and increased expression of Bax in HCT116 cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

286.28

Formula

C16H14O5

CAS 号

94344-54-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Seo HW, et al. Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells. Chem Biol Interact. 2020;327:109185.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Cathayanon H

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Cathayanon H 

Cathayanon H 是从纸桑树中分离出来。Cathayanon H 对人卵巢癌细胞具有细胞毒性。

Cathayanon H

Cathayanon H Chemical Structure

CAS No. : 1303438-51-8

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Cathayanon H is isolated from the paper mulberry tree. Cathayanon H is cytotoxic against human ovariancarcinoma cells[1].

分子量

424.49

Formula

C25H28O6

CAS 号

1303438-51-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Chin-Feng Chang, et al. Bioactive compounds from the bark of Broussonetia papyrifera after solid fermentation with a white rot fungus Perenniporia tephropora. Journal of Wood Chemistry and Technology, Volume 40, 2020 – Issue 5.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Cathayanon H

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Cathayanon H 

Cathayanon H 是从纸桑树中分离出来。Cathayanon H 对人卵巢癌细胞具有细胞毒性。

Cathayanon H

Cathayanon H Chemical Structure

CAS No. : 1303438-51-8

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Cathayanon H is isolated from the paper mulberry tree. Cathayanon H is cytotoxic against human ovariancarcinoma cells[1].

分子量

424.49

Formula

C25H28O6

CAS 号

1303438-51-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Chin-Feng Chang, et al. Bioactive compounds from the bark of Broussonetia papyrifera after solid fermentation with a white rot fungus Perenniporia tephropora. Journal of Wood Chemistry and Technology, Volume 40, 2020 – Issue 5.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Sappanchalcone

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Sappanchalcone 

Sappanchalcone 从 Caesalpinia sappan L. 中提取的黄酮类化合物,诱导人结肠癌细胞凋亡 (apoptosis)。

Sappanchalcone

Sappanchalcone Chemical Structure

CAS No. : 94344-54-4

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells[1].

体外研究
(In Vitro)

Sappanchalcone has a statistically significant effect on HCT116 cells than on SW480 cells (IC50= 37.33 μM and 54.23 μM, respectively). Sappanchalcone reduces MMP with a significant increase in ROS levels in human colon cancer cells. Sappanchalcone triggered phosphorylation of p53, which is involved in the activation of caspases and increased expression of Bax in HCT116 cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

286.28

Formula

C16H14O5

CAS 号

94344-54-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Seo HW, et al. Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells. Chem Biol Interact. 2020;327:109185.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Sappanchalcone

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Sappanchalcone 

Sappanchalcone 从 Caesalpinia sappan L. 中提取的黄酮类化合物,诱导人结肠癌细胞凋亡 (apoptosis)。

Sappanchalcone

Sappanchalcone Chemical Structure

CAS No. : 94344-54-4

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells[1].

体外研究
(In Vitro)

Sappanchalcone has a statistically significant effect on HCT116 cells than on SW480 cells (IC50= 37.33 μM and 54.23 μM, respectively). Sappanchalcone reduces MMP with a significant increase in ROS levels in human colon cancer cells. Sappanchalcone triggered phosphorylation of p53, which is involved in the activation of caspases and increased expression of Bax in HCT116 cells[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

286.28

Formula

C16H14O5

CAS 号

94344-54-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Seo HW, et al. Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells. Chem Biol Interact. 2020;327:109185.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Vindolinine

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Vindolinine 

Vindolinine 是可在 Catharanthus roseus 中发现的一个天然生物碱。

Vindolinine

Vindolinine Chemical Structure

CAS No. : 5980-02-9

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Vindolinine is a natural alkaloide that can be found in Catharanthus roseus[1].

分子量

336.43

Formula

C21H24N2O2

CAS 号

5980-02-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Werner Kohl, et al. Alkaloide aus Catharanthus roseus-Zellkulturen. Z. Naturforsch. 86b, 1153-1162 (1981).

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Vindolinine

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Vindolinine 

Vindolinine 是可在 Catharanthus roseus 中发现的一个天然生物碱。

Vindolinine

Vindolinine Chemical Structure

CAS No. : 5980-02-9

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Vindolinine is a natural alkaloide that can be found in Catharanthus roseus[1].

分子量

336.43

Formula

C21H24N2O2

CAS 号

5980-02-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Werner Kohl, et al. Alkaloide aus Catharanthus roseus-Zellkulturen. Z. Naturforsch. 86b, 1153-1162 (1981).

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Vindolinine

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Vindolinine 

Vindolinine 是可在 Catharanthus roseus 中发现的一个天然生物碱。

Vindolinine

Vindolinine Chemical Structure

CAS No. : 5980-02-9

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Vindolinine is a natural alkaloide that can be found in Catharanthus roseus[1].

分子量

336.43

Formula

C21H24N2O2

CAS 号

5980-02-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Werner Kohl, et al. Alkaloide aus Catharanthus roseus-Zellkulturen. Z. Naturforsch. 86b, 1153-1162 (1981).

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

6-Dehydrogingerdione

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

6-Dehydrogingerdione 

6-Dehydrogingerdione 通过活性氧介导 DR5 的增加,使人肝母细胞瘤 Heg2 细胞对 TRAIL 诱导的凋亡敏感。

6-Dehydrogingerdione

6-Dehydrogingerdione Chemical Structure

CAS No. : 76060-35-0

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

6-Dehydrogingerdione sensitizes human hepatoblastoma hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5[1].

体外研究
(In Vitro)

6-Dehydrogingerdione could trigger apoptotic cell death via both mitochondrial- and Fas receptor-mediated pathways[1].
6-Dehydrogingerdione (6-DG) up-regulates Ser-15 phosphorylation and evoked p53 nuclear translocation[1].
6-Dehydrogingerdione (6-DG) induces mitochondrial apoptotic pathway[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis[1]

Cell Line: Hep G2 cells.
Concentration: 0, 50, 100 μM.
Incubation Time: 24 h.
Result: Induced Apoptosis in Hep G2 Cells.

分子量

290.35

Formula

C17H22O4

CAS 号

76060-35-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Chung-Yi Chen, et al. 6-dehydrogingerdione sensitizes human hepatoblastoma Hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5. J Agric Food Chem. 2010 May 12;58(9):5604-11.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Ardisiacrispin B

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Ardisiacrispin B 

Ardisiacrispin B在多因素耐药癌细胞中显示细胞毒性作用,通过铁中毒和凋亡细胞死亡。

Ardisiacrispin B

Ardisiacrispin B Chemical Structure

CAS No. : 112766-96-8

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Ardisiacrispin B displays cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death[1].

分子量

1075.24

Formula

C53H86O22

CAS 号

112766-96-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Armelle T Mbaveng, et al. A naturally occuring triterpene saponin ardisiacrispin B displayed cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death. Phytomedicine. 2018 Apr 1;43:78-85.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

6-Dehydrogingerdione

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

6-Dehydrogingerdione 

6-Dehydrogingerdione 通过活性氧介导 DR5 的增加,使人肝母细胞瘤 Heg2 细胞对 TRAIL 诱导的凋亡敏感。

6-Dehydrogingerdione

6-Dehydrogingerdione Chemical Structure

CAS No. : 76060-35-0

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

6-Dehydrogingerdione sensitizes human hepatoblastoma hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5[1].

体外研究
(In Vitro)

6-Dehydrogingerdione could trigger apoptotic cell death via both mitochondrial- and Fas receptor-mediated pathways[1].
6-Dehydrogingerdione (6-DG) up-regulates Ser-15 phosphorylation and evoked p53 nuclear translocation[1].
6-Dehydrogingerdione (6-DG) induces mitochondrial apoptotic pathway[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis[1]

Cell Line: Hep G2 cells.
Concentration: 0, 50, 100 μM.
Incubation Time: 24 h.
Result: Induced Apoptosis in Hep G2 Cells.

分子量

290.35

Formula

C17H22O4

CAS 号

76060-35-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Chung-Yi Chen, et al. 6-dehydrogingerdione sensitizes human hepatoblastoma Hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5. J Agric Food Chem. 2010 May 12;58(9):5604-11.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

6-Dehydrogingerdione

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

6-Dehydrogingerdione 

6-Dehydrogingerdione 通过活性氧介导 DR5 的增加,使人肝母细胞瘤 Heg2 细胞对 TRAIL 诱导的凋亡敏感。

6-Dehydrogingerdione

6-Dehydrogingerdione Chemical Structure

CAS No. : 76060-35-0

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

6-Dehydrogingerdione sensitizes human hepatoblastoma hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5[1].

体外研究
(In Vitro)

6-Dehydrogingerdione could trigger apoptotic cell death via both mitochondrial- and Fas receptor-mediated pathways[1].
6-Dehydrogingerdione (6-DG) up-regulates Ser-15 phosphorylation and evoked p53 nuclear translocation[1].
6-Dehydrogingerdione (6-DG) induces mitochondrial apoptotic pathway[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis[1]

Cell Line: Hep G2 cells.
Concentration: 0, 50, 100 μM.
Incubation Time: 24 h.
Result: Induced Apoptosis in Hep G2 Cells.

分子量

290.35

Formula

C17H22O4

CAS 号

76060-35-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Chung-Yi Chen, et al. 6-dehydrogingerdione sensitizes human hepatoblastoma Hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5. J Agric Food Chem. 2010 May 12;58(9):5604-11.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Ardisiacrispin B

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Ardisiacrispin B 

Ardisiacrispin B在多因素耐药癌细胞中显示细胞毒性作用,通过铁中毒和凋亡细胞死亡。

Ardisiacrispin B

Ardisiacrispin B Chemical Structure

CAS No. : 112766-96-8

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Ardisiacrispin B displays cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death[1].

分子量

1075.24

Formula

C53H86O22

CAS 号

112766-96-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Armelle T Mbaveng, et al. A naturally occuring triterpene saponin ardisiacrispin B displayed cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death. Phytomedicine. 2018 Apr 1;43:78-85.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务