【编号】:SPR04183
【产品名称】:五味子酯D对照品
【规格】:10mg
【用途】:
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Schisandrone (Synonyms: 五味子酮)
Schisandrone 是一种从五味子的干果中分离得到的 4-芳基四氢呋喃木脂素。
Schisandrone Chemical Structure
CAS No. : 98619-25-1
规格 | 是否有货 | ||
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5 mg | 询价 | ||
10 mg | 询价 | ||
25 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
Schisandrone, a 4-aryltetralone lignan, is isolated from the dried fruits of Schisandra sphenanthera[1]. |
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分子量 |
356.41 |
Formula |
C21H24O5 |
CAS 号 |
98619-25-1 |
中文名称 |
五味子酮 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
【编号】:PR3265
【产品名称】:滇藏五味子素G对照品
【规格】:10mg
【用途】:
【编号】:PR0840
【产品名称】:披针叶五味子二内酯F对照品
【规格】:10mg
【用途】:
【编号】:PR0839
【产品名称】:披针叶五味子二内酯C对照品
【规格】:10mg
【用途】:
【编号】:PR1282
【产品名称】:开环新五味子酸A对照品
【规格】:10mg
【用途】:
【编号】:PR3359
【产品名称】:鹤庆五味子癸素对照品
【规格】:10mg
【用途】:
【编号】:PR3358
【产品名称】:鹤庆五味子辛素对照品
【规格】:10mg
【用途】:
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Schisandrin C (Synonyms: 五味子丙素; Schizandrin-C; Wuweizisu-C) 纯度: 99.95%
Schisandrin C (Schizandrin-C) 是从五味子中分离得到的一种植物化学木脂素 (lignan)。Schisandrin C 具有多种生物活性,包括抗癌、抗炎和抗氧化作用。Schisandrin C 可用于癌症、阿尔茨海默病、肝病的研究。Schisandrin C 诱导细胞凋亡 (apoptosis)。
Schisandrin C Chemical Structure
CAS No. : 61301-33-5
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
10 mg | ¥1500 | In-stock | |
50 mg | ¥5200 | In-stock | |
100 mg | ¥9200 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
Schisandrin C (Schizandrin-C) is a phytochemical lignan isolated from Schizandra chinensis[1]. Schisandrin C has diverse biological activities, including anticancer, anti-inflammatory and antioxidant effects. Schisandrin C can be used for cancer, alzheimer’s disease, and liver diseases research[2][3]. Schisandrin C induces cell apoptosis[1]. |
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体外研究 (In Vitro) |
Schisandrin C (25-100 μM; 48 hours) down-regulates expression levels of Bcl-2, Bcl-xL and a concomitant degradation of poly(ADP-ribose) polymerase (PARP). It also activates caspase-3 and -9 in U937 cells[2].Schisandrin C (25-100 μM; 48 hours) induces apoptosis in a dose-dependent manner. And the fragmentation of genomic DNA is also increased in U937 cells[1].Schisandrin C (25-100 μM; 72 hours) induces G1 arrest, it down-regulates cyclin D1, cyclin E, cyclin-dependent kinase (Cdk) 4 and E2Fs expression, and also exhibits inhibition of pRB, and up-regulation of the Cdk inhibitor p21(WAF1/CIP1)[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot Analysis[1]
Apoptosis Analysis[1]
Cell Cycle Analysis[1]
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体内研究 (In Vivo) |
Schisandrin C (lateral ventricle injection (i.c.v.); 15-150 μg/kg; 5 days) reduces Aβ1-42-induced memory deficits in the Y-maze test. Neurons in the hippocampus of SCH-C (15 μg/kg)-treated group returned to normal level, and and SCH-C group (150 μg/kg) has slight neuroprotective effects Aβ1-42-induced group. SCH-C (15 μg/kg) recoveres the activities of SOD and GSHPx and the ratios of GSH, decreases the levels of ChEtotal in the brain of the Aβ1–42-induced amnesic mice simultaneously[3]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
384.42 |
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Formula |
C22H24O6 |
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CAS 号 |
61301-33-5 |
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中文名称 |
五味子丙素 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 8.33 mg/mL (21.67 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
【编号】:PR3209
【产品名称】:异南五味子木脂宁对照品
【规格】:10mg
【用途】:
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Schisandrin B (Synonyms: 五味子乙素; γ-Schisandrin; Wuweizisu B) 纯度: 99.82%
Schisandrin B (γ-Schisandrin) 是从五味子中分离联苯环辛二烯衍生物,已被证明对啮齿类动物的肝脏和心脏的抗氧化作用。
Schisandrin B Chemical Structure
CAS No. : 61281-37-6
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
10 mM * 1 mL in DMSO | ¥1320 | In-stock | |
10 mg | ¥1200 | In-stock | |
50 mg | ¥3990 | In-stock | |
100 mg | 询价 | ||
200 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
Schisandrin B (γ-Schisandrin) is a dibenzocyclooctadiene derivative isolated from Fructus Schisandrae, has been shown to produce antioxidant effect on rodent liver and heart. IC50 value: Target: in vitro: Schisandrin B exhibits anti-inflammatory activity through modulation of the redox-sensitive transcription factors Nrf2 and NF-κB. SB inhibited mitogen-induced proliferation and cytokine secretion by lymphocytes [1]. Sch B can protect neuronal cells against oxidative challenge, presumably by functioning as a hormetic agent to sustain cellular redox homeostasis and mitoenergetic capacity in neuronal cells [2]. Sch B exerted significant neuroprotective effects against microglial-mediated inflammatory injury in microglia-neuron co-cultures. Sch B significantly downregulated pro-inflammatory cytokines, including nitrite oxide (NO), tumor necrosis factor (TNF)-α, prostaglandin E(2) (PGE(2)), interleukin (IL)-1β and IL-6 [3]. Sch B could inhibit TGF-β induced EMT of 4T1 cells and of primary human breast cancer cells [4]. in vivo: Similar anti-inflammatory effects of SB on lymphocyte proliferation and cytokine secretion were also observed in vivo [1]. Treatment with Sch B in CsA-treated mice significantly suppressed the elevation of blood urea nitrogen (BUN) and serum creatinine levels and attenuated the histopathological changes. Additionally, Sch B also decreased renal MDA levels and increased GSH levels in CsA-treated mice [5]. |
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分子量 |
400.46 |
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Formula |
C23H28O6 |
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CAS 号 |
61281-37-6 |
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中文名称 |
五味子乙素;五味子素乙 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 14.29 mg/mL (35.68 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
|
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参考文献 |
|
所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
【编号】:VIP(DS)1934
【产品名称】:五味子酯丙对照品
【规格】:5mg;HPLC≥98%
【用途】:
【编号】:PR0726
【产品名称】:异型南五味子丁素对照品
【规格】:10mg
【用途】:
【编号】:PR3950
【产品名称】:五味子二内酯A对照品
【规格】:10mg
【用途】:
【编号】:PR3356
【产品名称】:五味子酮对照品
【规格】:10mg
【用途】:
【编号】:PR3357
【产品名称】:五味子酚乙对照品
【规格】:10mg
【用途】: