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Lenampicillin hydrochloride (Synonyms: 盐酸仑氨苄西林; KBT 1585 hydrochloride) 纯度: 98.96%
Lenampicillin hydrochloride (KBT 1585 hydrochloride) 是氨苄西林的口服前药，是一种有效的-内酰胺类抗菌(beta-lactam antibacterial) 剂，可抑制细菌的青霉素结合蛋白(转肽酶)。与氨苄西林相比，Lenampicillin 有改善吸收、减少副作用的作用，并应用于化脓性皮肤软组织感染的研究。
Lenampicillin hydrochloride Chemical Structure
CAS No. : 80734-02-7
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 5 mg | ￥2800 | In-stock | |
| 10 mg | ￥4800 | In-stock | |
| 50 mg | 询价 | ||
| 100 mg | 询价 |
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Lenampicillin hydrochloride 相关产品
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| 生物活性 |
Lenampicillin hydrochloride (KBT 1585 hydrochloride) is an orally active prodrug of Ampicillin and is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins (transpeptidase). Lenampicillin hydrochloride has improved absorption and decreased side effects compares to Ampicillin and is applied in the investigation of the suppurative skin and soft tissue infection [1] [2] [3]. |
IC50 & Target |
IC50: bacterial penicillin-binding proteins (transpeptidase) |
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| 体内研究 (In Vivo) |
Lenampicillin hydrochloride (KBT-1585) (oral adminstration; 0-1000 mg/kg) does not lead to death in dogs, and maximum dose of in this acute toxicity study is recorded because of causing emesis[2].Lenampicillin hydrochloride (LAPC) are identified for it main metabolites in rat and dogs. The main metabolite in peripheral plasma is 2,3-butanediol in rats and dog, On the other hand, high levels of acetoin is found in portal plasma for early period after dosing of LAPC. These results shows that the biotransformation of promoiety in LAPC to acetoin carried out mainly in intestinal tissues, but acetoin is converted to 2,3-butanediol in liver[3]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
497.95 |
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| Formula |
C21H24ClN3O7S |
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| CAS 号 |
80734-02-7 |
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| 中文名称 |
盐酸仑氨苄西林；盐酸仑氨西林 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
-20°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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| 溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (200.82 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂： ——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
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| 参考文献 |
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