Perillyl alcohol(Synonyms: 紫苏醇)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Perillyl alcohol (Synonyms: 紫苏醇) 纯度: ≥95.0%

Perillyl alcohol 是一种单萜,可在不影响正常细胞的情况下诱导肿瘤细胞凋亡 (apoptosis)。

Perillyl alcohol(Synonyms: 紫苏醇)

Perillyl alcohol Chemical Structure

CAS No. : 536-59-4

规格 价格 是否有货 数量
100 mg ¥500 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Perillyl alcohol 相关产品

相关化合物库:

  • Natural Product Library Plus
  • Drug Repurposing Compound Library Plus
  • Clinical Compound Library Plus
  • Bioactive Compound Library Plus
  • Apoptosis Compound Library
  • Metabolism/Protease Compound Library
  • Natural Product Library
  • Anti-Cancer Compound Library
  • Clinical Compound Library
  • Human Endogenous Metabolite Compound Library
  • Drug Repurposing Compound Library
  • Medicine Food Homology Compound Library
  • Terpenoids Library
  • Traditional Chinese Medicine Monomer Library
  • Food Additive Library
  • Food-Sourced Compound Library
  • Rare Diseases Drug Library

生物活性

Perillyl alcohol, a monoterpene, is active in inducing apoptosis in tumor cells without affecting normal cells[1].

IC50 & Target

Human Endogenous Metabolite

 

Clinical Trial

分子量

152.23

Formula

C10H16O

CAS 号

536-59-4

中文名称

紫苏醇

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO : 250 mg/mL (1642.25 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 6.5690 mL 32.8450 mL 65.6901 mL
5 mM 1.3138 mL 6.5690 mL 13.1380 mL
10 mM 0.6569 mL 3.2845 mL 6.5690 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.17 mg/mL (14.25 mM); Clear solution

    此方案可获得 ≥ 2.17 mg/mL (14.25 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 21.7 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂: 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.17 mg/mL (14.25 mM); Clear solution

    此方案可获得 ≥ 2.17 mg/mL (14.25 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 21.7 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
  • 3.

    请依序添加每种溶剂: 10% DMSO    90% corn oil

    Solubility: ≥ 2.17 mg/mL (14.25 mM); Clear solution

    此方案可获得 ≥ 2.17 mg/mL (14.25 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 21.7 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 上海金畔生物科技有限公司 网站选购。
参考文献
  • [1]. Belanger JT. Perillyl alcohol: applications in oncology. Altern Med Rev. 1998 Dec;3(6):448-57.

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4-Isopropylbenzyl alcohol(Synonyms: 4-甲氧基苯甲醇)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

4-Isopropylbenzyl alcohol (Synonyms: 4-甲氧基苯甲醇)

4-Isopropylbenzyl alcohol 是来自金花茶 (Camellia nitidissima) 叶和花的精油。C. nitidissima 具有多种生物活性,包括抗氧化活性,抗癌活性,细胞毒性,以及抑制晚期糖基化终产物的形成。

4-Isopropylbenzyl alcohol(Synonyms: 4-甲氧基苯甲醇)

4-Isopropylbenzyl alcohol Chemical Structure

CAS No. : 536-60-7

规格 价格 是否有货 数量
10 mg ¥350 In-stock
50 mg ¥770 In-stock
100 mg   询价  
200 mg   询价  

* Please select Quantity before adding items.

4-Isopropylbenzyl alcohol 相关产品

相关化合物库:

  • Fragment Library

生物活性

4-Isopropylbenzyl alcohol is a chemical composition of the essential oils from the leaves and flowers of Camellia nitidissima. C. nitidissima possess multiple biological activities including antioxidant activity, anticancer activity, and cytotoxicity as well as inhibiting the formation of advanced glycation end-products[1].

分子量

150.22

Formula

C10H14O

CAS 号

536-60-7

中文名称

4-甲氧基苯甲醇

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO : 100 mg/mL (665.69 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 6.6569 mL 33.2845 mL 66.5690 mL
5 mM 1.3314 mL 6.6569 mL 13.3138 mL
10 mM 0.6657 mL 3.3285 mL 6.6569 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (16.64 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (16.64 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂: 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (16.64 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (16.64 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
  • 3.

    请依序添加每种溶剂: 10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (16.64 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (16.64 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 Shanghai Jinpan Biotech Co Ltd 网站选购。
参考文献
  • [1]. Wang B, et al. Essential oils and ethanol extract from Camellia nitidissima and evaluation of their biologicalactivity. J Food Sci Technol. 2018 Dec;55(12):5075-5081.

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Azido-PEG4-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Azido-PEG4-alcohol  纯度: ≥95.0%

Azido-PEG4-alcohol 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC。

Azido-PEG4-alcohol

Azido-PEG4-alcohol Chemical Structure

CAS No. : 86770-67-4

规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ¥940 In-stock
100 mg ¥850 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Azido-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

219.24

Formula

C8H17N3O4

CAS 号

86770-67-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

H2O : ≥ 100 mg/mL (456.12 mM)

DMSO : ≥ 100 mg/mL (456.12 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.5612 mL 22.8061 mL 45.6121 mL
5 mM 0.9122 mL 4.5612 mL 9.1224 mL
10 mM 0.4561 mL 2.2806 mL 4.5612 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂: PBS

    Solubility: 150 mg/mL (684.18 mM); Clear solution; Need ultrasonic

  • 2.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (11.40 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (11.40 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 3.

    请依序添加每种溶剂: 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (11.40 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (11.40 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
  • 4.

    请依序添加每种溶剂: 10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (11.40 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (11.40 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 上海金畔生物科技有限公司 网站选购。
参考文献
  • [1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Amino-PEG6-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Amino-PEG6-alcohol 

Amino-PEG6-alcohol 是一种不可降解 (non-cleavable) 的 6 单元 PEG 类 ADC linker,用于抗体偶联药物 (ADC) 的合成。Amino-PEG6-alcohol 也是一种基于 PEG 的 PROTAC linker,可用于 PROTAC 的合成。

Amino-PEG6-alcohol

Amino-PEG6-alcohol Chemical Structure

CAS No. : 39160-70-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Amino-PEG6-alcohol is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG6-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

Non-cleavable

 

PEGs

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

281.35

Formula

C12H27NO6

CAS 号

39160-70-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Yong Zu Kim, et al. Antibody-drug conjugates comprising branched linkers and methods related thereto. WO2017089895A1.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

N-Boc-PEG7-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

N-Boc-PEG7-alcohol 

N-Boc-PEG7-alcohol 是一种 PROTAC 连接桥,属于 PEG 类和 Alkyl/ether 类。N-Boc-PEG7-alcohol 可用于合成一系列 PROTAC 分子。N-Boc-PEG7-alcohol 是一种可降解 (cleavable) 的 ADC 连接桥,用于抗体药物结合物 (ADCs) 的合成。

N-Boc-PEG7-alcohol

N-Boc-PEG7-alcohol Chemical Structure

CAS No. : 1292268-13-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

N-Boc-PEG7-alcohol is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG7-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target[1]

Cleavable

 

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

425.51

Formula

C19H39NO9

CAS 号

1292268-13-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Julie Moreau, et al. Modular Synthesis of Bifunctional Linkers for Materials Science. European Journal of OrganicChemistry , 2011 ( 9 ) , 1641-1644.

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m-PEG4-CH2-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

m-PEG4-CH2-alcohol 

m-PEG4-CH2-alcohol 是一种基于 PEG 的 PROTAC linker,用于 PROTAC 合成。

m-PEG4-CH2-alcohol

m-PEG4-CH2-alcohol Chemical Structure

CAS No. : 145526-76-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

m-PEG4-CH2-alcohol is PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

222.28

Formula

C10H22O5

CAS 号

145526-76-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. KunioOka, et al. Thermochromism and solvatochromism of non-ionic polar polysilanes. Journal of Organometallic Chemistry.

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N-Boc-PEG9-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

N-Boc-PEG9-alcohol 

N-Boc-PEG9-alcohol 是一种 PROTAC 连接桥,属于 PEG 类和 Alkyl/ether 类。N-Boc-PEG9-alcohol 可用于合成一系列 PROTAC 分子。N-Boc-PEG9-alcohol 是一种可降解 (cleavable) 的 ADC 连接桥,用于抗体药物结合物 (ADCs) 的合成。

N-Boc-PEG9-alcohol

N-Boc-PEG9-alcohol Chemical Structure

CAS No. : 2112731-44-7

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生物活性

N-Boc-PEG9-alcohol is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG9-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

513.62

Formula

C23H47NO11

CAS 号

2112731-44-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nello Mainolfi, wt al. Irak degraders and uses thereof. US20190192668A1.

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N-Boc-PEG6-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

N-Boc-PEG6-alcohol 

N-Boc-PEG6-alcohol 是一种 PROTAC 连接桥,属于 PEG 类和 Alkyl/ether 类。N-Boc-PEG6-alcohol 可用于合成一系列 PROTAC 分子。N-Boc-PEG6-alcohol 是一种可降解 (cleavable) 的 ADC 连接桥,用于抗体药物结合物 (ADCs) 的合成。

N-Boc-PEG6-alcohol

N-Boc-PEG6-alcohol Chemical Structure

CAS No. : 331242-61-6

规格 价格 是否有货 数量
100 mg ¥900 In-stock
250 mg ¥1800 In-stock
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1 g   询价  

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生物活性

N-Boc-PEG6-alcohol is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG6-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

381.46

Formula

C17H35NO8

CAS 号

331242-61-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Nello Mainolfi, wt al. Irak degraders and uses thereof. US20190192668A1.

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Aminooxy-PEG4-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Aminooxy-PEG4-alcohol 

Aminooxy-PEG4-alcohol 是一种不可降解 (non-cleavable) 的含 4 个单元 PEG 的 ADC linker,可用于合成抗体偶联药物 (ADC)。Aminooxy-PEG4-alcohol 也是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

Aminooxy-PEG4-alcohol

Aminooxy-PEG4-alcohol Chemical Structure

CAS No. : 106492-60-8

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生物活性

Aminooxy-PEG4-alcohol is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG4-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

IC50 & Target[1][2]

PEGs

 

Non-cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

209.24

Formula

C8H19NO5

CAS 号

106492-60-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Heather D. Maynard, et al. Method of creating hydrogels through oxime bond formation. US20150202305A1.

    [2]. Murray BS, et al. Reactive thermoresponsive copolymer scaffolds. Chem Commun (Camb). 2010 Dec 7;46(45):8651-3.

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Aminooxy-PEG2-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Aminooxy-PEG2-alcohol 

Aminooxy-PEG2-alcohol 是一种不可降解 (non-cleavable) 的含 2 个单元 PEG 的 ADC linker,可用于合成抗体偶联药物 (ADC)。Aminooxy-PEG2-alcohol 也是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

Aminooxy-PEG2-alcohol

Aminooxy-PEG2-alcohol Chemical Structure

CAS No. : 185022-12-2

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生物活性

Aminooxy-PEG2-alcohol is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG2-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

IC50 & Target[1][2]

PEGs

 

Non-cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

121.14

Formula

C4H11NO3

CAS 号

185022-12-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Marek Kwiatkowski. Conjugates of biologically active molecules to functionalized polymers. WO2013186632A2.

    [2]. Murray BS, et al. Reactive thermoresponsive copolymer scaffolds. Chem Commun (Camb). 2010 Dec 7;46(45):8651-3.

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Azido-PEG5-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Azido-PEG5-alcohol 

Azido-PEG5-alcohol 是一种不可降解 (non-cleavable) 的含 5 个单元 PEG 的 ADC linker,可用于合成抗体偶联药物 (ADC)。Azido-PEG5-alcohol 也是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

Azido-PEG5-alcohol

Azido-PEG5-alcohol Chemical Structure

CAS No. : 86770-68-5

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生物活性

Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

IC50 & Target[1][2]

PEGs

 

Non-cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

263.29

Formula

C10H21N3O5

CAS 号

86770-68-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Zhang FL, et al. Molecular-target-based anticancer photosensitizer: synthesis and in vitro photodynamic activity of erlotinib-zinc(II) phthalocyanine conjugates. ChemMedChem. 2015 Feb;10(2):312-20.

    [2]. Nan JI, et al. Mertk degraders and uses thereof. WO2020010210A1.

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Propargyl-PEG7-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Propargyl-PEG7-alcohol 

Propargyl-PEG7-alcohol 是一种 PROTAC linker,属于 PEG 类。Propargyl-PEG7-OH 可用于合成一系列 PROTAC 分子。

Propargyl-PEG7-alcohol

Propargyl-PEG7-alcohol Chemical Structure

CAS No. : 1422023-54-8

规格 是否有货
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250 mg   询价  
500 mg   询价  

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生物活性

Propargyl-PEG7-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

364.43

Formula

C17H32O8

CAS 号

1422023-54-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Goswami LN, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery. Org Biomol Chem. 2013 Feb 21;11(7):1116-26.

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Propargyl-PEG6-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Propargyl-PEG6-alcohol 

Propargyl-PEG6-alcohol 是一种 PROTAC linker,属于 PEG 类。Propargyl-PEG6-OH 可用于合成一系列 PROTAC 分子。

Propargyl-PEG6-alcohol

Propargyl-PEG6-alcohol Chemical Structure

CAS No. : 944560-99-0

规格 是否有货
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250 mg   询价  
500 mg   询价  

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生物活性

Propargyl-PEG6-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

320.38

Formula

C15H28O7

CAS 号

944560-99-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Goswami LN, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery. Org Biomol Chem. 2013 Feb 21;11(7):1116-26.

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Propargyl-PEG4-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Propargyl-PEG4-alcohol 

Propargyl-PEG4-alcohol 是一种 PROTAC linker,属于 PEG 类。Propargyl-PEG4-alcohol 可用于合成一系列 PROTAC 分子。

Propargyl-PEG4-alcohol

Propargyl-PEG4-alcohol Chemical Structure

CAS No. : 87450-10-0

规格 价格 是否有货 数量
250 mg ¥2200 In-stock
500 mg ¥3450 In-stock
1 g   询价  
5 g   询价  

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生物活性

Propargyl-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

232.27

Formula

C11H20O5

CAS 号

87450-10-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.

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m-PEG3-CH2-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

m-PEG3-CH2-alcohol 

m-PEG3-CH2-alcohol 是一种基于PEG 的 PROTAC linker,可用于 PROTAC 的合成。

m-PEG3-CH2-alcohol

m-PEG3-CH2-alcohol Chemical Structure

CAS No. : 100688-48-0

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

m-PEG3-CH2-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

178.23

Formula

C8H18O4

CAS 号

100688-48-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

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Amino-PEG9-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Amino-PEG9-alcohol 

Amino-PEG9-alcohol 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

Amino-PEG9-alcohol

Amino-PEG9-alcohol Chemical Structure

CAS No. : 15332-95-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

Amino-PEG9-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

413.50

Formula

C18H39NO9

CAS 号

15332-95-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Sitterley KA, et al. Identification of Proprietary Amino Ethoxylates in Hydraulic Fracturing Wastewater Using Liquid Chromatography/Time-of-Flight Mass Spectrometry with Solid-Phase Extraction. Anal Chem. 2018 Sep 18;90(18):10927-10934.

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Biotin-PEG3-alcohol(Synonyms: (+)-Biotin-PEG3-OH)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Biotin-PEG3-alcohol (Synonyms: (+)-Biotin-PEG3-OH)

Biotin-PEG3-alcohol 是基于 PEG 结构的 PROTAC linker, 可以用来制备 PROTAC。

Biotin-PEG3-alcohol(Synonyms: (+)-Biotin-PEG3-OH)

Biotin-PEG3-alcohol Chemical Structure

CAS No. : 289714-02-9

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

Biotin-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

375.48

Formula

C16H29N3O5S

CAS 号

289714-02-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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Biotin-PEG6-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Biotin-PEG6-alcohol 

Biotin-PEG6-alcohol 是一种生物素标记的 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Biotin-PEG6-alcohol

Biotin-PEG6-alcohol Chemical Structure

CAS No. : 906099-89-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

Biotin-PEG6-alcohol is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

507.64

Formula

C22H41N3O8S

CAS 号

906099-89-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

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m-PEG10-alcohol(Synonyms: Decaethylene glycol monomethyl ether)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

m-PEG10-alcohol (Synonyms: Decaethylene glycol monomethyl ether)

m-PEG10-alcohol (Decaethylene glycol monomethyl ether) 是一种不可降解 (non-cleavable) 的含 10 个单元 PEG 的 ADC linker,可用于合成抗体偶联药物 (ADC)。m-PEG10-alcohol 还是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

m-PEG10-alcohol(Synonyms: Decaethylene glycol monomethyl ether)

m-PEG10-alcohol Chemical Structure

CAS No. : 27425-92-9

规格 是否有货
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生物活性

m-PEG10-alcohol (Decaethylene glycol monomethyl ether) is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG10-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

Non-cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

472.57

Formula

C21H44O11

CAS 号

27425-92-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Nnochiri Ekwuribe, et al. Calcitonin drug-oligomer conjugates, and uses thereof. US20040091452A1.

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m-PEG15-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

m-PEG15-alcohol 

m-PEG15-alcohol 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC。

m-PEG15-alcohol

m-PEG15-alcohol Chemical Structure

CAS No. : 2258654-78-1

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

m-PEG15-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

692.83

Formula

C31H64O16

CAS 号

2258654-78-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务