标签归档：aminooxy

Thiol PEG Aminooxy Cat. No. PG2-AOTH-5k 5000 Da 25 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Thiol PEG Aminooxy

Cat. No. PG2-AOTH-5k
Specification 5000 Da
Unit Size 25 mg
Price $485.00

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Similar names: Aminooxy PEG Thiol, Oxyamine PEG Thiol, HS-PEG-ONH2, Thiol PEG Oxyamine

Thiol PEG Aminooxy (HS-PEG-ONH2) is one of Nanocs heterobifunctional crosslinker PEGs that has a free thiol/sulfhydryl group on one end of PEG terminus and an aminooxy (-ONH2) functional group on the other PEG  terminus. Thiol group can bind to gold and other surface,  it can also react with many thiol reaction groups such as maleimide. Aminooxy group (-ONH2), on the other hand, can react with carbonyl groups with good stability. PEG linker between thiol and aminooxy offers better solublity and reduced steric hindrance.

Product specifications:

  • Form: Solid powder or semi-solid depends on molecular weight of PEG;
  • Functional groups: Sulfhydryl (-SH) and aminooxy (-ONH2);
  • Reactive to: Maleimide, metal surface, etc and carbonyl;
  • Solubility: Soluble in aqueous solution;

Storage:

  • Store at -20 0C.
Documents
  • SDS
  • DataSheet

Aminooxy-PEG2-azide

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Aminooxy-PEG2-azide 

Aminooxy-PEG2-azide 是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC 分子。Aminooxy-PEG2-azide 也是一种不可降解 (non-cleavable) 的含 2 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

Aminooxy-PEG2-azide

Aminooxy-PEG2-azide Chemical Structure

CAS No. : 1043426-13-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Aminooxy-PEG2-azide is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

IC50 & Target[1][2]

PEGs

 

Non-cleavable

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

190.20

Formula

C6H14N4O3
CAS 号

1043426-13-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. H. Tetsuo Uyeda, et al. Synthesis of surface ligands to prepare hydrophilic and biologically compatible quantum dots. doi: 10.1117/12.590494.

    [2]. Song, Ho Young, et al. Pyrrolobenzodiazepine dimer precursor and ligand-linker conjugate compound thereof.

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Aminooxy-PEG4-alcohol

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Aminooxy-PEG4-alcohol 

Aminooxy-PEG4-alcohol 是一种不可降解 (non-cleavable) 的含 4 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。Aminooxy-PEG4-alcohol 也是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC 分子。

Aminooxy-PEG4-alcohol

Aminooxy-PEG4-alcohol Chemical Structure

CAS No. : 106492-60-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Aminooxy-PEG4-alcohol is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG4-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

IC50 & Target[1][2]

PEGs

 

Non-cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

209.24

Formula

C8H19NO5
CAS 号

106492-60-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Heather D. Maynard, et al. Method of creating hydrogels through oxime bond formation. US20150202305A1.

    [2]. Murray BS, et al. Reactive thermoresponsive copolymer scaffolds. Chem Commun (Camb). 2010 Dec 7;46(45):8651-3.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Aminooxy-PEG1-azide

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Aminooxy-PEG1-azide 

Aminooxy-PEG1-azide 是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC。

Aminooxy-PEG1-azide

Aminooxy-PEG1-azide Chemical Structure

CAS No. : 2100306-70-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Aminooxy-PEG1-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

146.15

Formula

C4H10N4O2
CAS 号

2100306-70-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Aminooxy-PEG3-azide

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Aminooxy-PEG3-azide 

Aminooxy-PEG3-azide 是一种不可降解 (non-cleavable) 的含 3 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。Aminooxy-PEG3-azide 也是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC 分子。

Aminooxy-PEG3-azide

Aminooxy-PEG3-azide Chemical Structure

CAS No. : 1306615-51-9

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Aminooxy-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-C2-PEG3-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

IC50 & Target[1][2]

PEGs

 

Non-cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

234.25

Formula

C8H18N4O4
CAS 号

1306615-51-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Chanhyuk KIM, et al. Optimized chimeric receptor t cell switches and uses thereof. WO2016168766A1.

    [2]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Aminooxy-PEG4-azide

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Aminooxy-PEG4-azide 

Aminooxy-PEG4-azide 是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC。

Aminooxy-PEG4-azide

Aminooxy-PEG4-azide Chemical Structure

CAS No. : 2100306-61-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Aminooxy-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

278.31

Formula

C10H22N4O5
CAS 号

2100306-61-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Aminooxy-PEG2-alcohol

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Aminooxy-PEG2-alcohol 

Aminooxy-PEG2-alcohol 是一种不可降解 (non-cleavable) 的含 2 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。Aminooxy-PEG2-alcohol 也是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC 分子。

Aminooxy-PEG2-alcohol

Aminooxy-PEG2-alcohol Chemical Structure

CAS No. : 185022-12-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Aminooxy-PEG2-alcohol is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG2-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

IC50 & Target[1][2]

PEGs

 

Non-cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

121.14

Formula

C4H11NO3
CAS 号

185022-12-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Marek Kwiatkowski. Conjugates of biologically active molecules to functionalized polymers. WO2013186632A2.

    [2]. Murray BS, et al. Reactive thermoresponsive copolymer scaffolds. Chem Commun (Camb). 2010 Dec 7;46(45):8651-3.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Aminooxy-PEG1-propargyl

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Aminooxy-PEG1-propargyl 

Aminooxy-PEG1-propargyl 是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC。

Aminooxy-PEG1-propargyl

Aminooxy-PEG1-propargyl Chemical Structure

CAS No. : 1895922-69-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Aminooxy-PEG1-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

115.13

Formula

C5H9NO2
CAS 号

1895922-69-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Aminooxy-PEG3-propargyl

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Aminooxy-PEG3-propargyl 

Aminooxy-PEG3-propargyl 是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC 分子。

Aminooxy-PEG3-propargyl

Aminooxy-PEG3-propargyl Chemical Structure

CAS No. : 1807537-27-4

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Aminooxy-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

203.24

Formula

C9H17NO4
CAS 号

1807537-27-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Christopher Semko, et al. Rapamycin analogs as mtor inhibitors. WO2018204416A1.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Aminooxy-PEG3-C2-NH-Boc

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Aminooxy-PEG3-C2-NH-Boc 

Aminooxy-PEG3-C2-NH-Boc 是一种 PROTAC linker，属于 PEG 和 Alkyl/ether 类，可用于合成 PROTAC 分子。

Aminooxy-PEG3-C2-NH-Boc

Aminooxy-PEG3-C2-NH-Boc Chemical Structure

CAS No. : 2062663-65-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Aminooxy-PEG3-C2-NH-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

308.37

Formula

C13H28N2O6
CAS 号

2062663-65-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

PEG4-aminooxy-MMAF

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

PEG4-aminooxy-MMAF  纯度: 97.20%

PEG4-aminooxy-MMAF 是抗体偶联药物的一部分 (drug-linker conjugate for ADC)，具有抗癌活性，是由抗微管剂 MMAF 和不可降解 (non-cleavable) 的 PEG4 linker 连接而成。

PEG4-aminooxy-MMAF

PEG4-aminooxy-MMAF Chemical Structure

CAS No. : 1415246-35-3

规格 价格 是否有货 数量
5 mg ￥9950 In-stock
10 mg ￥14500 In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

生物活性

PEG4-aminooxy-MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the potent antitubulin agent MMAF, linked via the noncleavable PEG4[1].

IC50 & Target

Auristatin

 

分子量

923.19

Formula

C47H82N6O12
CAS 号

1415246-35-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, stored under nitrogen

*该产品在溶液状态不稳定，建议您现用现配，即刻使用。
溶解性数据
In Vitro: 

DMSO : 100 mg/mL (108.32 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.0832 mL 5.4160 mL 10.8320 mL
5 mM 0.2166 mL 1.0832 mL 2.1664 mL
10 mM 0.1083 mL 0.5416 mL 1.0832 mL

*

请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液；该产品在溶液状态不稳定，建议您现用现配，即刻使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂： 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (2.71 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.71 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂： 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (2.71 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.71 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
  • 3.

    请依序添加每种溶剂： 10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (2.71 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.71 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 上海金畔生物科技有限公司 网站选购。
参考文献

  • [1]. Samantha Congreve, et al. Antibody drug conjugates (ADC). Teknisk- naturvetenskaplig fakultet

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Boc-aminooxy-PEG1-propargyl

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Boc-aminooxy-PEG1-propargyl 

Boc-aminooxy-PEG1-propargyl 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Boc-aminooxy-PEG1-propargyl

Boc-aminooxy-PEG1-propargyl Chemical Structure

CAS No. : 1895922-72-1

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Boc-aminooxy-PEG1-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

215.25

Formula

C10H17NO4
CAS 号

1895922-72-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Boc-aminooxy-PEG4-propargyl

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Boc-aminooxy-PEG4-propargyl 

Boc-aminooxy-PEG4-propargyl 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Boc-aminooxy-PEG4-propargyl

Boc-aminooxy-PEG4-propargyl Chemical Structure

CAS No. : 1895922-77-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Boc-aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

347.40

Formula

C16H29NO7
CAS 号

1895922-77-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Boc-aminooxy-PEG5-propargyl

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Boc-aminooxy-PEG5-propargyl 

Boc-aminooxy-PEG5-propargyl 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Boc-aminooxy-PEG5-propargyl

Boc-aminooxy-PEG5-propargyl Chemical Structure

CAS No. : 2086688-98-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Boc-aminooxy-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

391.46

Formula

C18H33NO8
CAS 号

2086688-98-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务