Bis-sulfone-PEG4-Tetrazine

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Bis-sulfone-PEG4-Tetrazine 

Bis-sulfone-PEG4-Tetrazine 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Bis-sulfone-PEG4-Tetrazine

Bis-sulfone-PEG4-Tetrazine Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Bis-sulfone-PEG4-Tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

883.04

Formula

C42H54N6O11S2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1000.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Bis-sulfone-PEG4-Tetrazine

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Bis-sulfone-PEG4-Tetrazine 

Bis-sulfone-PEG4-Tetrazine 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Bis-sulfone-PEG4-Tetrazine

Bis-sulfone-PEG4-Tetrazine Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Bis-sulfone-PEG4-Tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

883.04

Formula

C42H54N6O11S2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1000.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Bis-sulfone-PEG4-Tetrazine

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Bis-sulfone-PEG4-Tetrazine 

Bis-sulfone-PEG4-Tetrazine 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Bis-sulfone-PEG4-Tetrazine

Bis-sulfone-PEG4-Tetrazine Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Bis-sulfone-PEG4-Tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

883.04

Formula

C42H54N6O11S2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1000.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Bis-PEG12-endo-BCN

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Bis-PEG12-endo-BCN 

Bis-PEG12-endo-BCN 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

Bis-PEG12-endo-BCN

Bis-PEG12-endo-BCN Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Bis-PEG12-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

分子量

941.15

Formula

C48H80N2O16

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Bis-PEG12-endo-BCN

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Bis-PEG12-endo-BCN 

Bis-PEG12-endo-BCN 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

Bis-PEG12-endo-BCN

Bis-PEG12-endo-BCN Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Bis-PEG12-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

分子量

941.15

Formula

C48H80N2O16

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Bis-PEG12-endo-BCN

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Bis-PEG12-endo-BCN 

Bis-PEG12-endo-BCN 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

Bis-PEG12-endo-BCN

Bis-PEG12-endo-BCN Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Bis-PEG12-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

分子量

941.15

Formula

C48H80N2O16

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

N-(Amino-PEG1)-N-bis(PEG2-propargyl)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

N-(Amino-PEG1)-N-bis(PEG2-propargyl) 

N-(Amino-PEG1)-N-bis(PEG2-propargyl) 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

N-(Amino-PEG1)-N-bis(PEG2-propargyl)

N-(Amino-PEG1)-N-bis(PEG2-propargyl) Chemical Structure

CAS No. : 2100306-47-4

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

356.46

Formula

C18H32N2O5

CAS 号

2100306-47-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

N-(Amino-PEG1)-N-bis(PEG2-propargyl)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

N-(Amino-PEG1)-N-bis(PEG2-propargyl) 

N-(Amino-PEG1)-N-bis(PEG2-propargyl) 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

N-(Amino-PEG1)-N-bis(PEG2-propargyl)

N-(Amino-PEG1)-N-bis(PEG2-propargyl) Chemical Structure

CAS No. : 2100306-47-4

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

356.46

Formula

C18H32N2O5

CAS 号

2100306-47-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

N-(Amino-PEG1)-N-bis(PEG2-propargyl)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

N-(Amino-PEG1)-N-bis(PEG2-propargyl) 

N-(Amino-PEG1)-N-bis(PEG2-propargyl) 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

N-(Amino-PEG1)-N-bis(PEG2-propargyl)

N-(Amino-PEG1)-N-bis(PEG2-propargyl) Chemical Structure

CAS No. : 2100306-47-4

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

356.46

Formula

C18H32N2O5

CAS 号

2100306-47-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) (hydrochloride)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) (hydrochloride) 

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride 是一种 PROTAC linker,属于 PEG 类。N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride 可用于合成 PROTAC 分子。

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) (hydrochloride)

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) (hydrochloride) Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

808.39

Formula

C35H70ClN3O15

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) (hydrochloride)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) (hydrochloride) 

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride 是一种 PROTAC linker,属于 PEG 类。N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride 可用于合成 PROTAC 分子。

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) (hydrochloride)

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) (hydrochloride) Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

808.39

Formula

C35H70ClN3O15

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) (hydrochloride)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) (hydrochloride) 

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride 是一种 PROTAC linker,属于 PEG 类。N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride 可用于合成 PROTAC 分子。

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) (hydrochloride)

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) (hydrochloride) Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

808.39

Formula

C35H70ClN3O15

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Bis-PEG4-TFP ester

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Bis-PEG4-TFP ester 

Bis-PEG4-TFP ester 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

Bis-PEG4-TFP ester

Bis-PEG4-TFP ester Chemical Structure

CAS No. : 1446282-42-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Bis-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

590.41

Formula

C24H22F8O8

CAS 号

1446282-42-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Bis-PEG4-TFP ester

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Bis-PEG4-TFP ester 

Bis-PEG4-TFP ester 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

Bis-PEG4-TFP ester

Bis-PEG4-TFP ester Chemical Structure

CAS No. : 1446282-42-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Bis-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

590.41

Formula

C24H22F8O8

CAS 号

1446282-42-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

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Bis-PEG4-TFP ester

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Bis-PEG4-TFP ester 

Bis-PEG4-TFP ester 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。

Bis-PEG4-TFP ester

Bis-PEG4-TFP ester Chemical Structure

CAS No. : 1446282-42-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Bis-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

590.41

Formula

C24H22F8O8

CAS 号

1446282-42-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one 

(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one (compound7) 是一种由 Curcuma kwangsiensis 植物中分离的天然产物。(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one 在巨噬细胞中能抑制 LPS 诱导产生的 NOIC50 为 8.93 μM。

(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one (6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one

(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one Chemical Structure

CAS No. : 1251830-57-5

规格 是否有货
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250 mg   询价  
500 mg   询价  

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生物活性

(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one (compound7) is a nature product isolated from rhizomes of Curcuma kwangsiensis. (6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one has inhibitory effect on NO production induced by LPS in macrophages with an IC50 value of 8.93 μM[1].

分子量

296.36

Formula

C19H20O3

CAS 号

1251830-57-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Li J, Zhao F, Li MZ, Chen LX, Qiu F. Diarylheptanoids from the Rhizomes of Curcuma kwangsiensis. J Nat Prod. 2010;73(10):1667-1671.

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1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one 

1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 6) 显示出抗增殖活性,26-L5 和 HT-1080 细胞的 ED50 值分别为 57.7 和 78.8 µM。1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one 抑制 B16 黑色素瘤4A5 细胞中的黑色素形成。1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one 具有研究皮肤性疾病的潜能。

1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one

1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one Chemical Structure

CAS No. : 332371-82-1

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 6) shows antiproliferative activity with ED50s of 57.7, 78.8 µM for 26-L5 and HT-1080 cells, respectively. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one inhibits melanogenesis in B16 melanoma 4A5 cells. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one has the potential for the research of skin disorders[1][2].

体外研究
(In Vitro)

1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 2) (1-10 µM) inhibits melanogenesis in B16 melanoma 4A5 cells with an IC50 of 1.99 µM[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

294.34

Formula

C19H18O3

CAS 号

332371-82-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Ali MS, et al. Six new diarylheptanoids from the seeds of Alpinia blepharocalyx. J Nat Prod. 2001 Mar;64(3):289-93.

    [2]. Matsumoto T, et al. Diarylheptanoids with inhibitory effects on melanogenesis from the rhizomes of Curcuma comosa in B16 melanoma cells. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5178-81.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Bis-Pro-5FU

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Bis-Pro-5FU 

Bis-Pro-5FU (Compound 4) 是一种 5-FU 前体,可增强5-氟尿嘧啶 (5-FU) 的口服生物利用度并提高其疗效。5-FU 是一种抗肿瘤抗代谢物,广泛用于结直肠癌和胰腺癌的研究。

Bis-Pro-5FU

Bis-Pro-5FU Chemical Structure

CAS No. : 2155827-07-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Bis-Pro-5FU (Compound 4) is a 5-FU precursor that confers oral bioavailability and increase the safety profile of 5-Fluorouracil (5-FU) chemotherapy regimens. 5-FU is an antineoplastic antimetabolite that is widely used for the research of colorectal and pancreatic cancer[1].

分子量

206.17

Formula

C10H7FN2O2

CAS 号

2155827-07-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Catherine Adam, et al. A 5-FU Precursor Designed to Evade Anabolic and Catabolic Drug Pathways and Activated by Pd Chemistry In Vitro and In Vivo. J Med Chem. 2022 Jan 13;65(1):552-561.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Bis-Pro-5FU

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Bis-Pro-5FU 

Bis-Pro-5FU (Compound 4) 是一种 5-FU 前体,可增强5-氟尿嘧啶 (5-FU) 的口服生物利用度并提高其疗效。5-FU 是一种抗肿瘤抗代谢物,广泛用于结直肠癌和胰腺癌的研究。

Bis-Pro-5FU

Bis-Pro-5FU Chemical Structure

CAS No. : 2155827-07-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Bis-Pro-5FU (Compound 4) is a 5-FU precursor that confers oral bioavailability and increase the safety profile of 5-Fluorouracil (5-FU) chemotherapy regimens. 5-FU is an antineoplastic antimetabolite that is widely used for the research of colorectal and pancreatic cancer[1].

分子量

206.17

Formula

C10H7FN2O2

CAS 号

2155827-07-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Catherine Adam, et al. A 5-FU Precursor Designed to Evade Anabolic and Catabolic Drug Pathways and Activated by Pd Chemistry In Vitro and In Vivo. J Med Chem. 2022 Jan 13;65(1):552-561.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Bis-Pro-5FU

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Bis-Pro-5FU 

Bis-Pro-5FU (Compound 4) 是一种 5-FU 前体,可增强5-氟尿嘧啶 (5-FU) 的口服生物利用度并提高其疗效。5-FU 是一种抗肿瘤抗代谢物,广泛用于结直肠癌和胰腺癌的研究。

Bis-Pro-5FU

Bis-Pro-5FU Chemical Structure

CAS No. : 2155827-07-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Bis-Pro-5FU (Compound 4) is a 5-FU precursor that confers oral bioavailability and increase the safety profile of 5-Fluorouracil (5-FU) chemotherapy regimens. 5-FU is an antineoplastic antimetabolite that is widely used for the research of colorectal and pancreatic cancer[1].

分子量

206.17

Formula

C10H7FN2O2

CAS 号

2155827-07-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Catherine Adam, et al. A 5-FU Precursor Designed to Evade Anabolic and Catabolic Drug Pathways and Activated by Pd Chemistry In Vitro and In Vivo. J Med Chem. 2022 Jan 13;65(1):552-561.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务