Cloxiquine(Synonyms: 5-氯-8-羟基喹啉; 5-Chloro-8-quinolinol)

发表于2024年4月11日由上海金畔生物科技有限公司

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Cloxiquine (Synonyms: 5-氯-8-羟基喹啉; 5-Chloro-8-quinolinol) 纯度: ≥98.0%

Cloxiquine (5-Chloro-8-quinolinol) 具有抗菌，抗真菌和抗阿米巴虫的功效。Cloxiquine 可用于结核病和皮肤病的研究。Cloxiquine 还可以通过激活 PPARγ 抑制黑素瘤细胞的生长和转移。

Cloxiquine Chemical Structure

CAS No. : 130-16-5

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Free Sample (0.1-0.5 mg)		Apply now
10 mM * 1 mL in DMSO	￥500	In-stock
500 mg	￥400	In-stock
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Cloxiquine 相关产品

•相关化合物库:

Bioactive Compound Library Plus
Anti-Infection Compound Library
Cell Cycle/DNA Damage Compound Library
Anti-Cancer Compound Library
Fragment Library
Anti-Aging Compound Library
Antifungal Compound Library
Antibacterial Compound Library
Glycolysis Compound Library
FDA Approved & Pharmacopeial Drug Library
Antiparasitic Compound library
Transcription Factor Targeted Library

生物活性

Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal and antiamoebic agent. Cloxiquine can be used for the research of tuberculosis and dermatoses. Cloxiquine suppresses the growth and metastasis of melanoma cells through activation of PPARγ^[1]^[2].

体外研究
(In Vitro)

Cloxiquine (cloxyquin) exhibits antituberculosis activities, with MICs ranging from 0.062 to 0.25 μg/mL against 9 standard strains and 150 Mycobacterium tuberculosis^[3].
Cloxiquine (0.5-10 μM; 24 h) suppresses both B16F10 and A375 cell growth in a dose-dependent manner^[2].
Cloxiquine (0.5-10 μM; 24 h) inhibits the migration of B16F10 and A375 cells^[2].
Cloxiquine (0.5-2.5 μM; 24 h) suppresses glycolysis in B16F10 cells^[2].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Cloxiquine (5-25 mg/kg; i.p. daily for 8 d) suppresses tumor growth in a mouse B16F10 melanoma xenograft model^[2].
Cloxiquine (5-25 mg/kg; i.p. daily for 14 d) suppresses tumor metastasis in mouse B16F10 melanoma lung metastatic model^[2].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

179.60

Formula

C₉H₆ClNO

CAS 号

130-16-5

中文名称

5-氯-8-羟基喹啉；氯羟喹

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO : 100 mg/mL (556.79 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	5.5679 mL	27.8396 mL	55.6793 mL
5 mM	1.1136 mL	5.5679 mL	11.1359 mL
10 mM	0.5568 mL	2.7840 mL	5.5679 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline

Solubility: ≥ 2.5 mg/mL (13.92 mM); Clear solution

此方案可获得 ≥ 2.5 mg/mL (13.92 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液
2.

请依序添加每种溶剂： 10% DMSO 90% corn oil

Solubility: ≥ 2.5 mg/mL (13.92 mM); Clear solution

此方案可获得 ≥ 2.5 mg/mL (13.92 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在上海金畔生物科技有限公司网站选购。

参考文献

[1]. Latosińska JN, et al. Supramolecular synthon pattern in solid clioquinol and cloxiquine (APIs of antibacterial, antifungal, antiaging and antituberculosis drugs) studied by ³⁵Cl NQR, ¹H-¹⁷O and ¹H-¹⁴N NQDR and DFT/QTAIM. J Mol Model. 2011 Jul;17(7):1781-800.

[2]. Zhang W, et, al. Cloxiquine, a traditional antituberculosis agent, suppresses the growth and metastasis of melanoma cells through activation of PPARγ. Cell Death Dis. 2019 May 28;10(6):404.

[3]. Hongmanee P, et, al. In vitro activities of cloxyquin (5-chloroquinolin-8-ol) against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2007 Mar;51(3):1105-6.

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6-Chloro-7-hydroxy-4-methylcoumarin

发表于2024年1月26日由上海金畔生物科技有限公司

6-Chloro-7-hydroxy-4-methylcoumarin

6-Chloro-7-hydroxy-4-methylcoumarin (compound 3) 是一种合成中间体。

6-Chloro-7-hydroxy-4-methylcoumarin Chemical Structure

CAS No. : 19492-02-5

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生物活性	6-Chloro-7-hydroxy-4-methylcoumarin (compound 3) an intermediate of pharmaceutical synthesis^[1].
分子量	210.61
Formula	C₁₀H₇ClO₃
CAS 号	19492-02-5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Hong Dai, et al. Excellent antitumor and antimetastatic activities based on novel coumarin/pyrazole oxime hybrids. Eur J Med Chem. 2019 Mar 15;166:470-479.

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6-Chloro-7-hydroxy-4-methylcoumarin

发表于2024年1月26日由上海金畔生物科技有限公司

6-Chloro-7-hydroxy-4-methylcoumarin

6-Chloro-7-hydroxy-4-methylcoumarin (compound 3) 是一种合成中间体。

6-Chloro-7-hydroxy-4-methylcoumarin Chemical Structure

CAS No. : 19492-02-5

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100 mg		询价
250 mg		询价
500 mg		询价

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生物活性	6-Chloro-7-hydroxy-4-methylcoumarin (compound 3) an intermediate of pharmaceutical synthesis^[1].
分子量	210.61
Formula	C₁₀H₇ClO₃
CAS 号	19492-02-5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Hong Dai, et al. Excellent antitumor and antimetastatic activities based on novel coumarin/pyrazole oxime hybrids. Eur J Med Chem. 2019 Mar 15;166:470-479.

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6-Chloro-7-hydroxy-4-methylcoumarin

发表于2024年1月26日由上海金畔生物科技有限公司

6-Chloro-7-hydroxy-4-methylcoumarin

6-Chloro-7-hydroxy-4-methylcoumarin (compound 3) 是一种合成中间体。

6-Chloro-7-hydroxy-4-methylcoumarin Chemical Structure

CAS No. : 19492-02-5

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	6-Chloro-7-hydroxy-4-methylcoumarin (compound 3) an intermediate of pharmaceutical synthesis^[1].
分子量	210.61
Formula	C₁₀H₇ClO₃
CAS 号	19492-02-5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Hong Dai, et al. Excellent antitumor and antimetastatic activities based on novel coumarin/pyrazole oxime hybrids. Eur J Med Chem. 2019 Mar 15;166:470-479.

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8-Chloro-cAMP

发表于2024年1月25日由上海金畔生物科技有限公司

8-Chloro-cAMP

8-Chloro-cAMP 是一种 cAMP 类似物，可诱导生长停滞，并调节 cAMP 依赖性 PKA 活性。8-Chloro-cAMP 具有抗癌活性。

8-Chloro-cAMP Chemical Structure

CAS No. : 41941-56-4

规格	价格	是否有货
5 mg	￥13800	In-stock
10 mg		询价
50 mg		询价

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8-Chloro-cAMP 相关产品

•相关化合物库:

Bioactive Compound Library Plus

生物活性

8-Chloro-cAMP is a cAMP analogue that induces growth arrest, and modulates cAMP-dependent PKA activity. 8-Chloro-cAMP has anticancer activity^[1].

体外研究
(In Vitro)

8-Chloro-cAMP markedly inhibits vascular smooth muscle cell (VSMC) proliferation in vitro, reduces protein kinase A (PKA) RIα subunit expression, and induces PKA RIIβ subunit expression^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

In rat bearing balloon injury, 8-Chloro-cAMP (12 mg/kg) reduces, in a dose-dependent manner, neointimal area and neointima/media ratio after balloon injury. 8-Chloro-cAMP shows a reduction of proliferative activity of VSMCs in vivo^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

363.65

Formula

C₁₀H₁₁ClN₅O₆P

CAS 号

41941-56-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

[1]. C Indolfi, et al. 8-chloro-cAMP inhibits smooth muscle cell proliferation in vitro and neointima formation induced by balloon injury in vivo. J Am Coll Cardiol. 2000 Jul;36(1):288-93.

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1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

发表于2024年1月18日由上海金畔生物科技有限公司

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

STAT3-IN-7 是一种 Sorafenib 的衍生物，可有效抑制 STAT3 的磷酸化。STAT3-IN-7 通过依赖 SHP-1 的 STAT3 失活诱导细胞凋亡 (apoptosis)，不抑制激酶活性，并具有抗癌作用。

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea Chemical Structure

CAS No. : 1313019-65-6

规格		是否有货
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250 mg		询价
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生物活性

STAT3-IN-7 is a Sorafenib analogue and potently inhibits the phosphorylation of STAT3. STAT3-IN-7 induces cell apoptosis through SHP-1 dependent STAT3 inactivation. STAT3-IN-7 does not inhibit kinase activity and has anticancer effects^[1].

IC₅₀ & Target^[1]

p-STAT3

体外研究
(In Vitro)

STAT3-IN-7 (SC-1; 1-10 μM; 48 hours; breast cancer cells) treatment demonstrates dose-dependent suppression of cell viability in all tested breast cancer cells^[1].
STAT3-IN-7 (SC-1; 1-10 μM; 36 hours; breast cancer cells) treatment induces potent apoptotic activity^[1].
STAT3-IN-7 (SC-1; 1-10 μM; 36 hours; breast cancer cells) treatment shows downregulation of p-STAT3 and its downstream proteins cyclin D1 and survivin in a dose-dependent manner in breast cancer cell lines^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:	HCC-1937, MDA-MB-231, MDA-MB-468, MDA-MB-453, SK-BR3 and MCF-7 cells
Concentration:	1 μM, 2 μM, 5 μM, 7.5 μM, 10 μM
Incubation Time:	48 hours
Result:	Demonstrated dose-dependent suppression of cell viability in all tested breast cancer cells.

Apoptosis Analysis^[1]

Cell Line:	HCC-1937, MDA-MB-231, MDA-MB-468, MDA-MB-453, SK-BR3 and MCF-7 cells
Concentration:	1 μM, 2 μM, 5 μM, 7.5 μM, 10 μM
Incubation Time:	36 hours
Result:	Induced potent apoptotic activity.

Western Blot Analysis^[1]

Cell Line:	HCC-1937, MDA-MB-231, MDA-MB-468, MDA-MB-453, SK-BR3 and MCF-7 cells
Concentration:	1 μM, 2 μM, 5 μM, 7.5 μM, 10 μM
Incubation Time:	36 hours
Result:	Showed downregulation of p-STAT3 and its downstream proteins cyclin D1 and survivin in a dose-dependent manner in breast cancer cell lines.

体内研究
(In Vivo)

STAT3-IN-7 (10 mg/kg; oral gavage; daily; for 28 days; female NCr athymic nude mice) treatment shows efficacious antitumor activity and p-STAT3 downregulation in MDA-MB-468 xenograft tumors^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Female NCr athymic nude mice (4-6 weeks of age) injected with breast cancer cells ^[1]
Dosage:	10 mg/kg
Administration:	Oral gavage; daily; for 28 days
Result:	Showed efficacious antitumor activity and p-STAT3 downregulation in MDA-MB-468 xenograft tumors.

分子量

431.80

Formula

C₂₁H₁₃ClF₃N₃O₂

CAS 号

1313019-65-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Chun-Yu Liu, et al. Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells. Breast Cancer Res. 2013;15(4):R63.

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1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

发表于2024年1月18日由上海金畔生物科技有限公司

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea Chemical Structure

CAS No. : 1313019-65-6

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

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生物活性

IC₅₀ & Target^[1]

p-STAT3

体外研究
(In Vitro)

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:	HCC-1937, MDA-MB-231, MDA-MB-468, MDA-MB-453, SK-BR3 and MCF-7 cells
Concentration:	1 μM, 2 μM, 5 μM, 7.5 μM, 10 μM
Incubation Time:	48 hours
Result:	Demonstrated dose-dependent suppression of cell viability in all tested breast cancer cells.

Apoptosis Analysis^[1]

Cell Line:	HCC-1937, MDA-MB-231, MDA-MB-468, MDA-MB-453, SK-BR3 and MCF-7 cells
Concentration:	1 μM, 2 μM, 5 μM, 7.5 μM, 10 μM
Incubation Time:	36 hours
Result:	Induced potent apoptotic activity.

Western Blot Analysis^[1]

Cell Line:	HCC-1937, MDA-MB-231, MDA-MB-468, MDA-MB-453, SK-BR3 and MCF-7 cells
Concentration:	1 μM, 2 μM, 5 μM, 7.5 μM, 10 μM
Incubation Time:	36 hours
Result:	Showed downregulation of p-STAT3 and its downstream proteins cyclin D1 and survivin in a dose-dependent manner in breast cancer cell lines.

体内研究
(In Vivo)

STAT3-IN-7 (10 mg/kg; oral gavage; daily; for 28 days; female NCr athymic nude mice) treatment shows efficacious antitumor activity and p-STAT3 downregulation in MDA-MB-468 xenograft tumors^[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Female NCr athymic nude mice (4-6 weeks of age) injected with breast cancer cells ^[1]
Dosage:	10 mg/kg
Administration:	Oral gavage; daily; for 28 days
Result:	Showed efficacious antitumor activity and p-STAT3 downregulation in MDA-MB-468 xenograft tumors.

分子量

431.80

Formula

C₂₁H₁₃ClF₃N₃O₂

CAS 号

1313019-65-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Chun-Yu Liu, et al. Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells. Breast Cancer Res. 2013;15(4):R63.

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1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

发表于2024年1月18日由上海金畔生物科技有限公司

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea Chemical Structure

CAS No. : 1313019-65-6

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

IC₅₀ & Target^[1]

p-STAT3

体外研究
(In Vitro)

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:	HCC-1937, MDA-MB-231, MDA-MB-468, MDA-MB-453, SK-BR3 and MCF-7 cells
Concentration:	1 μM, 2 μM, 5 μM, 7.5 μM, 10 μM
Incubation Time:	48 hours
Result:	Demonstrated dose-dependent suppression of cell viability in all tested breast cancer cells.

Apoptosis Analysis^[1]

Cell Line:	HCC-1937, MDA-MB-231, MDA-MB-468, MDA-MB-453, SK-BR3 and MCF-7 cells
Concentration:	1 μM, 2 μM, 5 μM, 7.5 μM, 10 μM
Incubation Time:	36 hours
Result:	Induced potent apoptotic activity.

Western Blot Analysis^[1]

Cell Line:	HCC-1937, MDA-MB-231, MDA-MB-468, MDA-MB-453, SK-BR3 and MCF-7 cells
Concentration:	1 μM, 2 μM, 5 μM, 7.5 μM, 10 μM
Incubation Time:	36 hours
Result:	Showed downregulation of p-STAT3 and its downstream proteins cyclin D1 and survivin in a dose-dependent manner in breast cancer cell lines.

体内研究
(In Vivo)

STAT3-IN-7 (10 mg/kg; oral gavage; daily; for 28 days; female NCr athymic nude mice) treatment shows efficacious antitumor activity and p-STAT3 downregulation in MDA-MB-468 xenograft tumors^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Female NCr athymic nude mice (4-6 weeks of age) injected with breast cancer cells ^[1]
Dosage:	10 mg/kg
Administration:	Oral gavage; daily; for 28 days
Result:	Showed efficacious antitumor activity and p-STAT3 downregulation in MDA-MB-468 xenograft tumors.

分子量

431.80

Formula

C₂₁H₁₃ClF₃N₃O₂

CAS 号

1313019-65-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Chun-Yu Liu, et al. Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells. Breast Cancer Res. 2013;15(4):R63.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Chloro-PEG5-chloride

发表于2024年1月9日由上海金畔生物科技有限公司

Chloro-PEG5-chloride

Chloro-PEG5-chloride 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Chloro-PEG5-chloride Chemical Structure

CAS No. : 5197-65-9

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

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生物活性

Chloro-PEG5-chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

275.17

Formula

C₁₀H₂₀Cl₂O₄

CAS 号

5197-65-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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Chloro-PEG2-Boc

发表于2024年1月9日由上海金畔生物科技有限公司

Chloro-PEG2-Boc

Chloro-PEG2-Boc 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Chloro-PEG2-Boc Chemical Structure

CAS No. : 1442085-43-9

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

Chloro-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

体外研究
(In Vitro)

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

238.71

Formula

C₁₀H₁₉ClO₄

CAS 号

1442085-43-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Chloro-PEG5-chloride

发表于2024年1月9日由上海金畔生物科技有限公司

Chloro-PEG5-chloride

Chloro-PEG5-chloride 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Chloro-PEG5-chloride Chemical Structure

CAS No. : 5197-65-9

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

Chloro-PEG5-chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

体外研究
(In Vitro)

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

275.17

Formula

C₁₀H₂₀Cl₂O₄

CAS 号

5197-65-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Chloro-PEG5-chloride

发表于2024年1月9日由上海金畔生物科技有限公司

Chloro-PEG5-chloride

Chloro-PEG5-chloride 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Chloro-PEG5-chloride Chemical Structure

CAS No. : 5197-65-9

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

Chloro-PEG5-chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

体外研究
(In Vitro)

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

275.17

Formula

C₁₀H₂₀Cl₂O₄

CAS 号

5197-65-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Chloro-PEG2-Boc

发表于2024年1月8日由上海金畔生物科技有限公司

Chloro-PEG2-Boc

Chloro-PEG2-Boc 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Chloro-PEG2-Boc Chemical Structure

CAS No. : 1442085-43-9

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

Chloro-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

体外研究
(In Vitro)

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

238.71

Formula

C₁₀H₁₉ClO₄

CAS 号

1442085-43-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Chloro-PEG2-Boc

发表于2024年1月8日由上海金畔生物科技有限公司

Chloro-PEG2-Boc

Chloro-PEG2-Boc 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Chloro-PEG2-Boc Chemical Structure

CAS No. : 1442085-43-9

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

Chloro-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

体外研究
(In Vitro)

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

238.71

Formula

C₁₀H₁₉ClO₄

CAS 号

1442085-43-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

8-(1-Chloro-2-hydroxy-3-methylbut-3-enyl)-7-methoxycoumarin

发表于2023年10月19日由上海金畔生物科技有限公司

8-(1-Chloro-2-hydroxy-3-methylbut-3-enyl)-7-methoxycoumarin

【编号】：SPR00482

【产品名称】：8-(1-Chloro-2-hydroxy-3-methylbut-3-enyl)-7-methoxycoumarin

【规格】：10mg

【用途】：

　　8-(1-Chloro-2-hydroxy-3-methylbut-3-enyl)-7-methoxycoumarin对照品

　　编号：SPR00482

　　英文名称：8-(1-Chloro-2-hydroxy-3-methylbut-3-enyl)-7-methoxycoumarin

　　CAS No.：131652-35-2

　　分子式：C15H15ClO4

　　分子量：294.731

　　类别：上海金畔生物科技有限公司，中药对照品

　　作为标准品，对照品或者供研究用，不能直接用于人体。

2-(4-Chloro-3-hydroxy-1-butynyl)-5-(1,3-pentadiynyl)thiophene

发表于2023年10月16日由上海金畔生物科技有限公司

2-(4-Chloro-3-hydroxy-1-butynyl)-5-(1,3-pentadiynyl)thiophene

【编号】：SPR00499

【产品名称】：2-(4-Chloro-3-hydroxy-1-butynyl)-5-(1,3-pentadiynyl)thiophene

【规格】：10mg

【用途】：

　　2-(4-Chloro-3-hydroxy-1-butynyl)-5-(1,3-pentadiynyl)thiophene对照品

　　编号：SPR00499

　　英文名称：2-(4-Chloro-3-hydroxy-1-butynyl)-5-(1,3-pentadiynyl)thiophene

　　CAS No.：26905-70-4

　　分子式：C13H9ClOs

　　分子量：248.724

　　包装: 棕色小玻璃瓶，按客户需求包装。

　　类别：上海金畔生物科技有限公司，中药对照品

　　作为标准品，对照品或者供研究用，不能直接用于人体。

1-Chloro-6-(5-(prop-1-ynyl)thiophen-2-yl)hexa-3,5-diyn-2-ol

发表于2023年10月15日由上海金畔生物科技有限公司

1-Chloro-6-(5-(prop-1-ynyl)thiophen-2-yl)hexa-3,5-diyn-2-ol

【编号】：SPR00498

【产品名称】：1-Chloro-6-(5-(prop-1-ynyl)thiophen-2-yl)hexa-3,5-diyn-2-ol

【规格】：10mg

【用途】：

　　1-Chloro-6-(5-(prop-1-ynyl)thiophen-2-yl)hexa-3,5-diyn-2-ol对照品

　　编号：SPR00498

　　英文名称：1-Chloro-6-(5-(prop-1-ynyl)thiophen-2-yl)hexa-3,5-diyn-2-ol

　　CAS No.：78876-52-5

　　分子式：C13H9ClOs

　　分子量：248.724

　　类别：上海金畔生物科技有限公司，中药对照品

　　作为标准品，对照品或者供研究用，不能直接用于人体。

17-Acetyloxy-6-chloro-1α-chloromethylpregna-4,6-diene-3,20-dione对照品_17183-98-1

发表于2023年9月7日由上海金畔生物科技有限公司

17-Acetyloxy-6-chloro-1α-chloromethylpregna-4,6-diene-3,20-dione对照品

【编号】：VIP(XL)80423

【产品名称】：17-Acetyloxy-6-chloro-1α-chloromethylpregna-4,6-diene-3,20-dione对照品

【规格】：5mg；98%

【用途】：

　　17-Acetyloxy-6-chloro-1α-chloromethylpregna-4,6-diene-3,20-dione对照品

　　编号：VIP(XL)80423

　　英文：17-Acetyloxy-6-chloro-1α-chloromethylpregna-4,6-diene-3,20-dione

　　CAS号：17183-98-1

　　分子式：C24H30Cl2O4
17-Acetyloxy-6-chloro-1α-chloromethylpregna-4,6-diene-3,20-dione对照品_17183-98-1

　　规格：可定做：10mg；20mg；50mg；100mg

　　声明：此对照品、标准品由上海金畔生物科技有限公司提供网站查询购买服务

　　注：点击cas，或者搜索：名称、编号、cas均可查询产品信息

(p-Chloro-D-Phe6,Leu17)-VIP (human, bovine, porcine, rat) 编码 [102805-45-8]

发表于2023年7月31日由上海金畔生物科技有限公司

名称	(p-Chloro-D-Phe6,Leu17)-VIP (human, bovine, porcine, rat)
编码	[102805-45-8]
别名	(p-Chloro-D-Phe6,Leu17)-VIP (human, bovine, porcine, rat)
纯度	80%，90%，95%，98%，99%
重量	1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写）	HSDAV-p-chloro-D-FTDNYTRLRKQLAVKKYLNSILN-NH2
序列（三字母缩写）	His-Ser-Asp-Ala-Val-p-chloro-D-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2
基本描述
溶解度
分子量	0
化学式
存储条件	Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents
Figures
Reference
C端
N端
化学桥

2-Chloro-11-cyclopentyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one_1521197-43-2

发表于2023年7月1日由上海金畔生物科技有限公司

2-Chloro-11-cyclopentyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one

【编号】：VIP(XL)81294

【产品名称】：2-Chloro-11-cyclopentyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one

【规格】：5mg

【用途】：

　　2-Chloro-11-cyclopentyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one对照品

　　编号：VIP(XL)81294

　　英文：2-Chloro-11-cyclopentyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one

　　CAS号：1521197-43-2

　　分子式：C16H15ClN4O
2-Chloro-11-cyclopentyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one_1521197-43-2

　　规格：可定做：10mg；25mg；50mg；100mg

　　声明：此对照品、标准品由上海金畔生物科技有限公司提供网站查询购买服务

　　注：点击cas，或者搜索：名称、编号、cas均可查询产品信息

赛默飞Alfa aesar官网

赛默飞Acros试剂中国官网 Alfa aesar阿法埃莎中国代理商

标签归档：chloro

Cloxiquine(Synonyms: 5-氯-8-羟基喹啉; 5-Chloro-8-quinolinol)

Cloxiquine 相关产品

•相关化合物库:

6-Chloro-7-hydroxy-4-methylcoumarin

6-Chloro-7-hydroxy-4-methylcoumarin

6-Chloro-7-hydroxy-4-methylcoumarin

8-Chloro-cAMP

8-Chloro-cAMP 相关产品

•相关化合物库:

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

Chloro-PEG5-chloride

Chloro-PEG2-Boc

Chloro-PEG5-chloride

Chloro-PEG5-chloride

Chloro-PEG2-Boc

Chloro-PEG2-Boc

8-(1-Chloro-2-hydroxy-3-methylbut-3-enyl)-7-methoxycoumarin

8-(1-Chloro-2-hydroxy-3-methylbut-3-enyl)-7-methoxycoumarin对照品

2-(4-Chloro-3-hydroxy-1-butynyl)-5-(1,3-pentadiynyl)thiophene

2-(4-Chloro-3-hydroxy-1-butynyl)-5-(1,3-pentadiynyl)thiophene对照品

1-Chloro-6-(5-(prop-1-ynyl)thiophen-2-yl)hexa-3,5-diyn-2-ol

1-Chloro-6-(5-(prop-1-ynyl)thiophen-2-yl)hexa-3,5-diyn-2-ol对照品

17-Acetyloxy-6-chloro-1α-chloromethylpregna-4,6-diene-3,20-dione对照品_17183-98-1

17-Acetyloxy-6-chloro-1α-chloromethylpregna-4,6-diene-3,20-dione对照品

(p-Chloro-D-Phe6,Leu17)-VIP (human, bovine, porcine, rat) 编码 [102805-45-8]

2-Chloro-11-cyclopentyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one_1521197-43-2

2-Chloro-11-cyclopentyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one对照品