上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Dusquetide TFA (Synonyms: SGX942 TFA)
Dusquetide (SGX942) TFA 是第一类天然防御调节因子 (IDR)。Dusquetide TFA 通过与 p62 结合调节 PAMPs 和 DAMPs 的天然免疫应答。Dusquetide TFA 在减轻炎症和增加细菌感染清除方面都显示出活性。
Dusquetide TFA Chemical Structure
规格 | 价格 | 是否有货 | 数量 |
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1 mg | ¥2200 | In-stock | |
5 mg | ¥5600 | 询价 | |
10 mg | ¥9500 | 询价 | |
50 mg | 询价 | ||
100 mg | 询价 |
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生物活性 |
Dusquetide (SGX942) TFA is a first-in-class innate defense regulator (IDR). Dusquetide TFA modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide TFA shows activity in both reducing inflammation and increasing clearance of bacterial infection[1]. DAMPs: damage-associated molecular patterns; PAMPs: pathogen-associated molecular patterns |
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体内研究 (In Vivo) |
Dusquetide (SGX942) TFA (25 mg/kg; i.v.; days 0, 4, 7, 10, and 14) shows no increase in tumor growth or worsening of survival and a trend towards decreased tumor growth and improvement in survival with radiation[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
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Clinical Trial |
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分子量 |
667.72 |
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Formula |
C27H48F3N9O7 |
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Sequence |
{Arg}{Ile}{Val}{Pro}{Ala}-NH2 |
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Sequence Shortening |
RIVPA-NH2 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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参考文献 |
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