标签归档：goat

GOAT-IN-1

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

GOAT-IN-1 

GOAT-IN-1 是胃促生长素 O-酰基转移酶 (GOAT) 的抑制剂，可用于预防或研究肥胖、糖尿病、高脂血症、非酒精性脂肪肝、脂肪性肝炎、骨骼肌减少症、食欲控制、酒精/麻醉性依赖、阿尔茨海默症、帕金森、脑血管疾病与老年痴呆、脑卒中、脑梗死、心血管疾病、肿瘤等。

GOAT-IN-1

GOAT-IN-1 Chemical Structure

CAS No. : 1452473-54-9

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生物活性

GOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT), which could be useful for the prophylaxis or treatment of obesity, diabetes, hyperlipidemia, metabolic, non-alcoholic fatty liver, steatohepatitis, sarcopenia, appetite control, alcohol/narcotic dependence, Alzheimer’s disease, Parkinson’s disease, cerebrovascular dementia, cerebral apoplexy, cerebral infarction, cardic disease, some kind of tumors.

体外研究
(In Vitro)

The inhibitory activity of GOAT-IN-1 (Example 16) for human GOAT is 101% with the concentration of 10 μM[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

415.81

Formula

C18H13ClF3NO3S
CAS 号

1452473-54-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. WO 2013125732.

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