上海慧泰立式万用电炉四联4KW(停产)
技术参数:
注:4 KW 6 KW都不配电源插头。
上海慧泰立式万用电炉四联4KW(停产)
技术参数:
注:4 KW 6 KW都不配电源插头。
上海慧泰立式万用电炉双联2KW(停产)
技术参数:
注:4 KW 6 KW都不配电源插头。
上海慧泰封闭电炉六联6KW
用途概述
封闭电炉,是工矿企业、医院、学校、科研院所、农办环保等部门实验室的加热设备,用途广泛、炉温可电子式无极(选配)或机械有级调节,使用方便、安全节能。
产品特点
封闭电炉采用进口能量调节开关,炉体由优质钢板制成,炉盘与加热丝模具冲压而成,有效的增加热能的散发,保证炉盘的使用寿命。电源实现对加热功率的无极调速,机械式采用短路电阻丝实现对加热的有极调控,操作方便、节能、安全、发热器件寿命长,方便各种加热器具的使用。
技术参数
型号 | 单联1KW | 双联2KW | 四联4KW | 六联6KW |
额定电压 | 220V50Hz | 380V50Hz | ||
稳定功率 | 1KW | 2KW | 4KW | 6KW |
外径尺寸 W×D×H(mm) |
170×200×155 | 340×200×155 | 680×200×155 | 1200×1200×155 |
上海慧泰封闭电炉四联4KW
用途概述
封闭电炉,是工矿企业、医院、学校、科研院所、农办环保等部门实验室的加热设备,用途广泛、炉温可电子式无极(选配)或机械有级调节,使用方便、安全节能。
产品特点
封闭电炉采用进口能量调节开关,炉体由优质钢板制成,炉盘与加热丝模具冲压而成,有效的增加热能的散发,保证炉盘的使用寿命。电源实现对加热功率的无极调速,机械式采用短路电阻丝实现对加热的有极调控,操作方便、节能、安全、发热器件寿命长,方便各种加热器具的使用。
技术参数
型号 | 单联1KW | 双联2KW | 四联4KW | 六联6KW |
额定电压 | 220V50Hz | 380V50Hz | ||
稳定功率 | 1KW | 2KW | 4KW | 6KW |
外径尺寸 W×D×H(mm) |
170×200×155 | 340×200×155 | 680×200×155 | 1200×1200×155 |
上海慧泰封闭电炉双联2KW
用途概述
封闭电炉,是工矿企业、医院、学校、科研院所、农办环保等部门实验室的加热设备,用途广泛、炉温可电子式无极(选配)或机械有级调节,使用方便、安全节能。
产品特点
封闭电炉采用进口能量调节开关,炉体由优质钢板制成,炉盘与加热丝模具冲压而成,有效的增加热能的散发,保证炉盘的使用寿命。电源实现对加热功率的无极调速,机械式采用短路电阻丝实现对加热的有极调控,操作方便、节能、安全、发热器件寿命长,方便各种加热器具的使用。
技术参数
型号 | 单联1KW | 双联2KW | 四联4KW | 六联6KW |
额定电压 | 220V50Hz | 380V50Hz | ||
稳定功率 | 1KW | 2KW | 4KW | 6KW |
外径尺寸 W×D×H(mm) |
170×200×155 | 340×200×155 | 680×200×155 | 1200×1200×155 |
上海慧泰封闭电炉单联1KW
用途概述
封闭电炉,是工矿企业、医院、学校、科研院所、农办环保等部门实验室的加热设备,用途广泛、炉温可电子式无极(选配)或机械有级调节,使用方便、安全节能。
产品特点
封闭电炉采用进口能量调节开关,炉体由优质钢板制成,炉盘与加热丝模具冲压而成,有效的增加热能的散发,保证炉盘的使用寿命。电源实现对加热功率的无极调速,机械式采用短路电阻丝实现对加热的有极调控,操作方便、节能、安全、发热器件寿命长,方便各种加热器具的使用。
技术参数
型号 | 单联1KW | 双联2KW | 四联4KW | 六联6KW |
额定电压 | 220V50Hz | 380V50Hz | ||
稳定功率 | 1KW | 2KW | 4KW | 6KW |
外径尺寸 W×D×H(mm) |
170×200×155 | 340×200×155 | 680×200×155 | 1200×1200×155 |
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
KW-2478 纯度: 98.62%
KW-2478 是一种 Hsp90α 抑制剂,IC50 值为 3.8 nM,对多种人类血液肿瘤细胞具有抗肿瘤活性。
KW-2478 Chemical Structure
CAS No. : 819812-04-9
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
10 mM * 1 mL in DMSO | ¥2402 | In-stock | |
5 mg | ¥1900 | In-stock | |
10 mg | ¥2900 | In-stock | |
50 mg | ¥7600 | In-stock | |
100 mg | ¥11000 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
KW-2478 is an inhibitor of Hsp90α, with an IC50 of 3.8 nM, and has antitumor activity against various human hematological tumor cells. |
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IC50 & Target[1] |
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体外研究 (In Vitro) |
KW-2478 is an inhibitor of Hsp90, with an IC50 of 3.8 nM for Hsp90α. KW-2478 shows anti-proliferative activity against multiple myeloma (MM) and non-Hodgkin’s lymphoma (NHL), with GI50s of 0.30 μM (OPM-2/GFP), 0.34 μM (KMS-11), 0.39 μM (RPMI 8226), 0.12 μM (NCI-H929), 0.36 μM (Raji), 0.098 μM (SR), and 0.33 μM μM (SC-1). KW-2478 also inhibits the transcription of c-Maf and Cyclin D1 genes by mainly suppressing the function of Cdk9[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
KW-2478 (25-200 mg/kg, i.v.) inhibits tumor growth in combined immunodeficiency (SCID) mice bearing NCI-H929 cells, without body weight loss. KW-2478 (100 mg/kg, i.v.) causes degradation of the Hsp90 client proteins (IGF-1Rβ, c-Raf-1, Cdk9) levels and dephosphorylated Erk1/2 proteins in NCI-H929 tumors of mice[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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Clinical Trial |
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分子量 |
574.66 |
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Formula |
C30H42N2O9 |
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CAS 号 |
819812-04-9 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 200 mg/mL (348.03 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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Cell Assay [1] |
The cells are plated into 96-well plates and treated with KW-2478. After 72 hours of cultivation, cell viability is determined using WST-1. WST reagent is added to the wells, followed by incubation for 4 hours at 37°C. After that, the absorbance at 450 nm with reference at 650 nm is measured with a microplate spectrophotometer[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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Animal Administration [1] |
Mice[1] 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
参考文献 |
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所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
KW-2449 纯度: 99.72%
KW-2449是多靶点激酶抑制剂,对FLT3,ABL,ABLT315I和 Aurora kinase 的 IC50 值分别为6.6,14,4 和 48 nM。
KW-2449 Chemical Structure
CAS No. : 1000669-72-6
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
Free Sample (0.1-0.5 mg) | Apply now | ||
10 mM * 1 mL in DMSO | ¥550 | In-stock | |
5 mg | ¥500 | In-stock | |
10 mg | ¥663 | In-stock | |
50 mg | ¥2790 | In-stock | |
100 mg | ¥5115 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
KW-2449 is a multi-targeted kinase inhibitor of FLT3, ABL, ABLT315I and Aurora kinase with IC50s of 6.6, 14, 4 and 48 nM, respectively. |
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IC50 & Target[1] |
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体外研究 (In Vitro) |
KW-2449 shows growth inhibitory activities against FLT3/ITD-, FLT3/D835Y-, and wt-FLT3/FL-expressing 32D cells, MOLM-13 and MV4;11 with GI50 values of 0.024, 0.046, 0.014, 0.024, and 0.011 μM, respectively. KW-2449 suppresses the phosphorylations of FLT3 (P-FLT3) and its downstream molecule phospho-STAT5 (P-STAT5) in MOLM-13 cells in a dose-dependent manner. KW-2449 increases the percentage of cells in the G1 phase of the cell cycle and reciprocally reduced the percentage of cells in the S phase, resulting in the increase of apoptotic cell population[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
Oral administration of KW-2449 shows dose-dependent and significant tumor growth inhibition in FLT3-mutated xenograft model with minimum bone marrow suppression. In FLT3 wild-type human leukemia, it induces the reduction of phosphorylated histone H3, G2/M arrest, and apoptosis. In imatinib-resistant leukemia, KW-2449 contributes to release of the resistance by the simultaneous down-regulation of BCR/ABL and Aurora kinases. Furthermore, the antiproliferative activity of KW-2449 is confirmed in primary samples from AML and imatinib-resistant patients. The inhibitory activity of KW-2449 is not affected by the presence of human plasma protein, such as α1-acid glycoprotein[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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Clinical Trial |
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分子量 |
332.40 |
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Formula |
C20H20N4O |
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CAS 号 |
1000669-72-6 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : ≥ 50 mg/mL (150.42 mM) * “≥” means soluble, but saturation unknown. 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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Cell Assay [1] |
Cell viability is determined by the sodium 3′-[1-(phenylaminocarbonyl)-3, 4-tetrazolium]-bis (4-methoxy-6-nitro) benzene sulfonic acid hydrate assay after incubation with or without KW-2449 for 72 hours at 37°C. The number of viable cells is determined using the Cell Proliferation Kit II[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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Animal Administration [1] |
Mice: SCID mice are subcutaneously inoculated with MOLM-13 cells. Five days after inoculation, tumor volume is measured using the Antitumor test system II. The 25 mice with tumors ranging from 90 to 130 mm3 are selected and randomized using the Antitumor test system II. From the day of randomization, vehicle (0.5 wt/vol% MC400) or KW-2449 (2.5, 5.0, 10, and 20 mg/kg) is orally administered to mice twice a day for 14 days. Tumor volume is measured twice a week during the treatment[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
参考文献 |
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所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务