Methyl-PEG2-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Methyl-PEG2-alcohol 

Methyl-PEG2-alcohol 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Methyl-PEG2-alcohol

Methyl-PEG2-alcohol Chemical Structure

CAS No. : 111-77-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

Methyl-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

120.15

Formula

C5H12O3

CAS 号

111-77-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Methyl-PEG2-alcohol

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Methyl-PEG2-alcohol 

Methyl-PEG2-alcohol 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Methyl-PEG2-alcohol

Methyl-PEG2-alcohol Chemical Structure

CAS No. : 111-77-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Methyl-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

120.15

Formula

C5H12O3

CAS 号

111-77-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Methyl-PEG3-bromide

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Methyl-PEG3-bromide 

Methyl-PEG3-bromide 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Methyl-PEG3-bromide

Methyl-PEG3-bromide Chemical Structure

CAS No. : 72593-77-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Methyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

227.10

Formula

C7H15BrO3

CAS 号

72593-77-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Methyl-PEG3-bromide

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Methyl-PEG3-bromide 

Methyl-PEG3-bromide 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Methyl-PEG3-bromide

Methyl-PEG3-bromide Chemical Structure

CAS No. : 72593-77-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Methyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

227.10

Formula

C7H15BrO3

CAS 号

72593-77-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

7-Aminomethyl-10-methyl-11-fluoro camptothecin

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

7-Aminomethyl-10-methyl-11-fluoro camptothecin 

7-Aminomethyl-10-methyl-11-fluoro camptothecin 是 MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (HY-132158,化合物 21a) 的毒素分子,可用于合成喜树碱抗体偶联药物 (ADC)。

7-Aminomethyl-10-methyl-11-fluoro camptothecin

7-Aminomethyl-10-methyl-11-fluoro camptothecin Chemical Structure

CAS No. : 2378616-23-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

7-Aminomethyl-10-methyl-11-fluoro camptothecin is a cytotoxin of MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (HY-132158,compound 21a). 7-Aminomethyl-10-methyl-11-fluoro camptothecin can be used for the synthesis of camptothecin antibody-drug conjugate (ADC)[1].

分子量

409.41

Formula

C22H20FN3O4

CAS 号

2378616-23-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Li W, et, al. Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates. ACS Med Chem Lett. 2019 Sep 6;10(10):1386-1392.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

7-Aminomethyl-10-methyl-11-fluoro camptothecin

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

7-Aminomethyl-10-methyl-11-fluoro camptothecin 

7-Aminomethyl-10-methyl-11-fluoro camptothecin 是 MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (HY-132158,化合物 21a) 的毒素分子,可用于合成喜树碱抗体偶联药物 (ADC)。

7-Aminomethyl-10-methyl-11-fluoro camptothecin

7-Aminomethyl-10-methyl-11-fluoro camptothecin Chemical Structure

CAS No. : 2378616-23-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

7-Aminomethyl-10-methyl-11-fluoro camptothecin is a cytotoxin of MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (HY-132158,compound 21a). 7-Aminomethyl-10-methyl-11-fluoro camptothecin can be used for the synthesis of camptothecin antibody-drug conjugate (ADC)[1].

分子量

409.41

Formula

C22H20FN3O4

CAS 号

2378616-23-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Li W, et, al. Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates. ACS Med Chem Lett. 2019 Sep 6;10(10):1386-1392.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

7-Aminomethyl-10-methyl-11-fluoro camptothecin

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

7-Aminomethyl-10-methyl-11-fluoro camptothecin 

7-Aminomethyl-10-methyl-11-fluoro camptothecin 是 MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (HY-132158,化合物 21a) 的毒素分子,可用于合成喜树碱抗体偶联药物 (ADC)。

7-Aminomethyl-10-methyl-11-fluoro camptothecin

7-Aminomethyl-10-methyl-11-fluoro camptothecin Chemical Structure

CAS No. : 2378616-23-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

7-Aminomethyl-10-methyl-11-fluoro camptothecin is a cytotoxin of MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (HY-132158,compound 21a). 7-Aminomethyl-10-methyl-11-fluoro camptothecin can be used for the synthesis of camptothecin antibody-drug conjugate (ADC)[1].

分子量

409.41

Formula

C22H20FN3O4

CAS 号

2378616-23-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Li W, et, al. Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates. ACS Med Chem Lett. 2019 Sep 6;10(10):1386-1392.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Thalidomide-5-methyl

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Thalidomide-5-methyl 

Thalidomide-5-methyl 是基于 Thalidomide 的 CRBN 配体,用于CRBN 蛋白招募。

Thalidomide-5-methyl

Thalidomide-5-methyl Chemical Structure

CAS No. : 40313-92-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1].

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

272.26

Formula

C14H12N2O4

CAS 号

40313-92-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. George W. Muller, et al. Substituted 2-(2,6 dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing TNFα levels. Patent US5874448A.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Thalidomide-5-methyl

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Thalidomide-5-methyl 

Thalidomide-5-methyl 是基于 Thalidomide 的 CRBN 配体,用于CRBN 蛋白招募。

Thalidomide-5-methyl

Thalidomide-5-methyl Chemical Structure

CAS No. : 40313-92-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1].

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

272.26

Formula

C14H12N2O4

CAS 号

40313-92-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. George W. Muller, et al. Substituted 2-(2,6 dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing TNFα levels. Patent US5874448A.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Thalidomide-5-methyl

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Thalidomide-5-methyl 

Thalidomide-5-methyl 是基于 Thalidomide 的 CRBN 配体,用于CRBN 蛋白招募。

Thalidomide-5-methyl

Thalidomide-5-methyl Chemical Structure

CAS No. : 40313-92-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1].

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

272.26

Formula

C14H12N2O4

CAS 号

40313-92-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. George W. Muller, et al. Substituted 2-(2,6 dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing TNFα levels. Patent US5874448A.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

3-Methyl-2-quinoxalinecarboxylic acid-d4(Synonyms: MQCA-d4)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

3-Methyl-2-quinoxalinecarboxylic acid-d4 (Synonyms: MQCA-d4)

3-Methylquinoxaline-2-carboxylic acid-d4 (MQCA-d4) 是 3-Methyl-2-quinoxalinecarboxylic acid 的氘代物。3-Methyl-2-quinoxalinecarboxylic acid (MQCA) 是 Quinocetone 或 Olaquindox 的重要 N 氧化物还原性代谢产物,可通过 S 期细胞周期停滞来有效抑制张氏肝细胞生长。

3-Methyl-2-quinoxalinecarboxylic acid-d4(Synonyms: MQCA-d4)

3-Methyl-2-quinoxalinecarboxylic acid-d4 Chemical Structure

CAS No. : 2244217-93-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

3-Methylquinoxaline-2-carboxylic acid-d4 (MQCA-d4) is the deuterium labeled 3-Methyl-2-quinoxalinecarboxylic acid. 3-Methyl-2-quinoxalinecarboxylic acid (MQCA), an important N-oxide reductive metabolite of Quinocetone or Olaquindox, potently inhibits the growth of Chang liver cells through S phase arrest of the cell cycle[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

192.21

Formula

C10H4D4N2O2

CAS 号

2244217-93-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Keyu Zhang , et al. Cytotoxicity and Genotoxicity of 1,4-bisdesoxyquinocetone, 3-methylquinoxaline-2-carboxylic Acid (MQCA) in Human Hepatocytes. Res Vet Sci. 2012 Dec;93(3):1393-401.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

3-Methyl-2-quinoxalinecarboxylic acid-d4(Synonyms: MQCA-d4)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

3-Methyl-2-quinoxalinecarboxylic acid-d4 (Synonyms: MQCA-d4)

3-Methylquinoxaline-2-carboxylic acid-d4 (MQCA-d4) 是 3-Methyl-2-quinoxalinecarboxylic acid 的氘代物。3-Methyl-2-quinoxalinecarboxylic acid (MQCA) 是 Quinocetone 或 Olaquindox 的重要 N 氧化物还原性代谢产物,可通过 S 期细胞周期停滞来有效抑制张氏肝细胞生长。

3-Methyl-2-quinoxalinecarboxylic acid-d4(Synonyms: MQCA-d4)

3-Methyl-2-quinoxalinecarboxylic acid-d4 Chemical Structure

CAS No. : 2244217-93-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

3-Methylquinoxaline-2-carboxylic acid-d4 (MQCA-d4) is the deuterium labeled 3-Methyl-2-quinoxalinecarboxylic acid. 3-Methyl-2-quinoxalinecarboxylic acid (MQCA), an important N-oxide reductive metabolite of Quinocetone or Olaquindox, potently inhibits the growth of Chang liver cells through S phase arrest of the cell cycle[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

192.21

Formula

C10H4D4N2O2

CAS 号

2244217-93-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Keyu Zhang , et al. Cytotoxicity and Genotoxicity of 1,4-bisdesoxyquinocetone, 3-methylquinoxaline-2-carboxylic Acid (MQCA) in Human Hepatocytes. Res Vet Sci. 2012 Dec;93(3):1393-401.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

3-Methyl-2-quinoxalinecarboxylic acid-d4(Synonyms: MQCA-d4)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

3-Methyl-2-quinoxalinecarboxylic acid-d4 (Synonyms: MQCA-d4)

3-Methylquinoxaline-2-carboxylic acid-d4 (MQCA-d4) 是 3-Methyl-2-quinoxalinecarboxylic acid 的氘代物。3-Methyl-2-quinoxalinecarboxylic acid (MQCA) 是 Quinocetone 或 Olaquindox 的重要 N 氧化物还原性代谢产物,可通过 S 期细胞周期停滞来有效抑制张氏肝细胞生长。

3-Methyl-2-quinoxalinecarboxylic acid-d4(Synonyms: MQCA-d4)

3-Methyl-2-quinoxalinecarboxylic acid-d4 Chemical Structure

CAS No. : 2244217-93-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

3-Methylquinoxaline-2-carboxylic acid-d4 (MQCA-d4) is the deuterium labeled 3-Methyl-2-quinoxalinecarboxylic acid. 3-Methyl-2-quinoxalinecarboxylic acid (MQCA), an important N-oxide reductive metabolite of Quinocetone or Olaquindox, potently inhibits the growth of Chang liver cells through S phase arrest of the cell cycle[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

192.21

Formula

C10H4D4N2O2

CAS 号

2244217-93-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Keyu Zhang , et al. Cytotoxicity and Genotoxicity of 1,4-bisdesoxyquinocetone, 3-methylquinoxaline-2-carboxylic Acid (MQCA) in Human Hepatocytes. Res Vet Sci. 2012 Dec;93(3):1393-401.

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Methyl 3,4-dihydroxybenzoate-d3(Synonyms: Protocatechuic acid methyl ester-d3; Methyl protocatechuate-d3)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Methyl 3,4-dihydroxybenzoate-d3 (Synonyms: Protocatechuic acid methyl ester-d3; Methyl protocatechuate-d3)

Methyl 3,4-dihydroxybenzoate-d3 (Protocatechuic acid methyl ester-d3) 是 Methyl 3,4-dihydroxybenzoate 的氘代物。Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester) 是绿茶中发现的抗氧化多酚的主要代谢产物。 抗氧化和抗炎作用。

Methyl 3,4-dihydroxybenzoate-d3(Synonyms: Protocatechuic acid methyl ester-d3;  Methyl protocatechuate-d3)

Methyl 3,4-dihydroxybenzoate-d3 Chemical Structure

CAS No. : 2734001-51-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Methyl 3,4-dihydroxybenzoate-d3 (Protocatechuic acid methyl ester-d3) is the deuterium labeled Methyl 3,4-dihydroxybenzoate. Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

171.17

Formula

C8H5D3O4

CAS 号

2734001-51-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Ameeramja J, et al. Protocatechuic acid methyl ester ameliorates fluoride toxicity in A549 cells. Food Chem Toxicol. 2017 Nov;109(Pt 2):941-950.

    [3]. Ameeramja J, et al. Protocatechuic acid methyl ester modulates fluoride induced pulmonary toxicity in rats. Food Chem Toxicol. 2018 Aug;118:235-244.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Methyl 3,4-dihydroxybenzoate-d3(Synonyms: Protocatechuic acid methyl ester-d3; Methyl protocatechuate-d3)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Methyl 3,4-dihydroxybenzoate-d3 (Synonyms: Protocatechuic acid methyl ester-d3; Methyl protocatechuate-d3)

Methyl 3,4-dihydroxybenzoate-d3 (Protocatechuic acid methyl ester-d3) 是 Methyl 3,4-dihydroxybenzoate 的氘代物。Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester) 是绿茶中发现的抗氧化多酚的主要代谢产物。 抗氧化和抗炎作用。

Methyl 3,4-dihydroxybenzoate-d3(Synonyms: Protocatechuic acid methyl ester-d3;  Methyl protocatechuate-d3)

Methyl 3,4-dihydroxybenzoate-d3 Chemical Structure

CAS No. : 2734001-51-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Methyl 3,4-dihydroxybenzoate-d3 (Protocatechuic acid methyl ester-d3) is the deuterium labeled Methyl 3,4-dihydroxybenzoate. Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

171.17

Formula

C8H5D3O4

CAS 号

2734001-51-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Ameeramja J, et al. Protocatechuic acid methyl ester ameliorates fluoride toxicity in A549 cells. Food Chem Toxicol. 2017 Nov;109(Pt 2):941-950.

    [3]. Ameeramja J, et al. Protocatechuic acid methyl ester modulates fluoride induced pulmonary toxicity in rats. Food Chem Toxicol. 2018 Aug;118:235-244.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Methyl 3,4-dihydroxybenzoate-d3(Synonyms: Protocatechuic acid methyl ester-d3; Methyl protocatechuate-d3)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Methyl 3,4-dihydroxybenzoate-d3 (Synonyms: Protocatechuic acid methyl ester-d3; Methyl protocatechuate-d3)

Methyl 3,4-dihydroxybenzoate-d3 (Protocatechuic acid methyl ester-d3) 是 Methyl 3,4-dihydroxybenzoate 的氘代物。Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester) 是绿茶中发现的抗氧化多酚的主要代谢产物。 抗氧化和抗炎作用。

Methyl 3,4-dihydroxybenzoate-d3(Synonyms: Protocatechuic acid methyl ester-d3;  Methyl protocatechuate-d3)

Methyl 3,4-dihydroxybenzoate-d3 Chemical Structure

CAS No. : 2734001-51-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Methyl 3,4-dihydroxybenzoate-d3 (Protocatechuic acid methyl ester-d3) is the deuterium labeled Methyl 3,4-dihydroxybenzoate. Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

171.17

Formula

C8H5D3O4

CAS 号

2734001-51-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Ameeramja J, et al. Protocatechuic acid methyl ester ameliorates fluoride toxicity in A549 cells. Food Chem Toxicol. 2017 Nov;109(Pt 2):941-950.

    [3]. Ameeramja J, et al. Protocatechuic acid methyl ester modulates fluoride induced pulmonary toxicity in rats. Food Chem Toxicol. 2018 Aug;118:235-244.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Methyl 3,4-dihydroxybenzoate-d3-1

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Methyl 3,4-dihydroxybenzoate-d3-1 

Methyl 3,4-dihydroxybenzoate-d3-1 是 Methyl 3,4-dihydroxybenzoate 的氘代物。Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester) 是绿茶中发现的抗氧化多酚的主要代谢产物。 抗氧化和抗炎作用。

Methyl 3,4-dihydroxybenzoate-d3-1

Methyl 3,4-dihydroxybenzoate-d3-1 Chemical Structure

CAS No. : 2733147-54-9

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Methyl 3,4-dihydroxybenzoate-d3-1 is the deuterium labeled Methyl 3,4-dihydroxybenzoate. Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

171.17

Formula

C8H5D3O4

CAS 号

2733147-54-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Ameeramja J, et al. Protocatechuic acid methyl ester ameliorates fluoride toxicity in A549 cells. Food Chem Toxicol. 2017 Nov;109(Pt 2):941-950.

    [3]. Ameeramja J, et al. Protocatechuic acid methyl ester modulates fluoride induced pulmonary toxicity in rats. Food Chem Toxicol. 2018 Aug;118:235-244.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Methyl 3,4-dihydroxybenzoate-d3-1

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Methyl 3,4-dihydroxybenzoate-d3-1 

Methyl 3,4-dihydroxybenzoate-d3-1 是 Methyl 3,4-dihydroxybenzoate 的氘代物。Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester) 是绿茶中发现的抗氧化多酚的主要代谢产物。 抗氧化和抗炎作用。

Methyl 3,4-dihydroxybenzoate-d3-1

Methyl 3,4-dihydroxybenzoate-d3-1 Chemical Structure

CAS No. : 2733147-54-9

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Methyl 3,4-dihydroxybenzoate-d3-1 is the deuterium labeled Methyl 3,4-dihydroxybenzoate. Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

171.17

Formula

C8H5D3O4

CAS 号

2733147-54-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Ameeramja J, et al. Protocatechuic acid methyl ester ameliorates fluoride toxicity in A549 cells. Food Chem Toxicol. 2017 Nov;109(Pt 2):941-950.

    [3]. Ameeramja J, et al. Protocatechuic acid methyl ester modulates fluoride induced pulmonary toxicity in rats. Food Chem Toxicol. 2018 Aug;118:235-244.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Methyl 3,4-dihydroxybenzoate-d3-1

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Methyl 3,4-dihydroxybenzoate-d3-1 

Methyl 3,4-dihydroxybenzoate-d3-1 是 Methyl 3,4-dihydroxybenzoate 的氘代物。Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester) 是绿茶中发现的抗氧化多酚的主要代谢产物。 抗氧化和抗炎作用。

Methyl 3,4-dihydroxybenzoate-d3-1

Methyl 3,4-dihydroxybenzoate-d3-1 Chemical Structure

CAS No. : 2733147-54-9

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Methyl 3,4-dihydroxybenzoate-d3-1 is the deuterium labeled Methyl 3,4-dihydroxybenzoate. Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

171.17

Formula

C8H5D3O4

CAS 号

2733147-54-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Ameeramja J, et al. Protocatechuic acid methyl ester ameliorates fluoride toxicity in A549 cells. Food Chem Toxicol. 2017 Nov;109(Pt 2):941-950.

    [3]. Ameeramja J, et al. Protocatechuic acid methyl ester modulates fluoride induced pulmonary toxicity in rats. Food Chem Toxicol. 2018 Aug;118:235-244.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

N-Methyl Pemetrexed-d3

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

N-Methyl Pemetrexed-d3 

N-Methyl Pemetrexed-d3 是 N-Methyl pemetrexed 的氘代物。N-Methyl pemetrexed 是 Pemetrexed 的一种杂质。N-Methyl pemetrexed 是一种抗叶酸细胞毒剂,可用于癌症研究。

N-Methyl Pemetrexed-d3

N-Methyl Pemetrexed-d3 Chemical Structure

CAS No. : 2714410-41-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

N-Methyl Pemetrexed-d3 is the deuterium labeled N-Methyl pemetrexed. N-Methyl pemetrexed is an impurity of Pemetrexed. Pemetrexed is an antifolate cytotoxic agent that can be used for the research of cancer[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

444.46

Formula

C21H20D3N5O6

CAS 号

2714410-41-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Warner A, et, al. Development of a purity control strategy for pemetrexed disodium and validation of associated analytical methodology. J Pharm Biomed Anal. 2015 Feb;105:46-54.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务