Pendulone(Synonyms: 垂崖豆藤异黄烷醌)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Pendulone (Synonyms: 垂崖豆藤异黄烷醌)

Pendulone 是一种异黄烷醌,具有良好的抗疟原虫活性,IC50 为 7.0 µM。Pendulone 还具有抗利什曼原虫、抗菌和抗癌活性。

Pendulone(Synonyms: 垂崖豆藤异黄烷醌)

Pendulone Chemical Structure

CAS No. : 69359-09-7

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Pendulone is a isoflavanquinone with good antiplasmodial activity with an IC50 of 7.0 µM. Pendulone also has antileishmanial, antibacterial and anticancer activity[1][2].

体外研究
(In Vitro)

Pendulone displays moderate antiproliferative activity against the A2780 human ovarian cancer cell line, with an IC50 value 19.6 µM[1].
Pendulone displays an IC50 value of 0.43 µg/mL, against L. donovani promastigotes. Pendulone also displays antibacterial activity against Staphylococcus aureus and methicillin-resistant S. aureus (each IC50 of 1.44 µg/mL)[2].
Pendulone exhibits moderate anticancer activity against human cancer cell lines (SK-MEL, KB, BT-549 and SK-OV-3) with IC50 values of 5.5 and 10.5 μg/mL. Pendulone also shows moderate cytotoxicities against monkey kidney fibroblasts (VERO) and pig kidney epithelial cells (LLC-PK11)[2].
Pendulone shows strong inhibition on the effect of the cell cycle induced by 12-O-tetradecanoyl-phorbol-13-acetate (TPA) in Raji cells[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Pendulone shows potent anti-tumor-promoting activity for an in vivo two-stage carcinogenesis test of mouse skin using 7,12-dimethylbenz[a]-anthracene and TPA[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

316.31

Formula

C17H16O6

CAS 号

69359-09-7

中文名称

垂崖豆藤异黄烷醌

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Qingxi Su, et al. Antiplasmodial Isoflavanes and Pterocarpans from Apoplanesia paniculata. Planta Med. 2015 Aug;81(12-13):1128-32.

    [2]. Aziz A Rahman, et al. Antiparasitic and antimicrobial isoflavanquinones from Abrus schimperi. Nat Prod Commun. 2011 Nov;6(11):1645-50.

    [3]. T Konoshima, et al. Anti-tumor promoting activities of isoflavonoids from Wistaria brachybotrys. Biol Pharm Bull. 1997 Aug;20(8):865-8.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Pendulone(Synonyms: 垂崖豆藤异黄烷醌)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Pendulone (Synonyms: 垂崖豆藤异黄烷醌)

Pendulone 是一种异黄烷醌,具有良好的抗疟原虫活性,IC50 为 7.0 µM。Pendulone 还具有抗利什曼原虫、抗菌和抗癌活性。

Pendulone(Synonyms: 垂崖豆藤异黄烷醌)

Pendulone Chemical Structure

CAS No. : 69359-09-7

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Pendulone is a isoflavanquinone with good antiplasmodial activity with an IC50 of 7.0 µM. Pendulone also has antileishmanial, antibacterial and anticancer activity[1][2].

体外研究
(In Vitro)

Pendulone displays moderate antiproliferative activity against the A2780 human ovarian cancer cell line, with an IC50 value 19.6 µM[1].
Pendulone displays an IC50 value of 0.43 µg/mL, against L. donovani promastigotes. Pendulone also displays antibacterial activity against Staphylococcus aureus and methicillin-resistant S. aureus (each IC50 of 1.44 µg/mL)[2].
Pendulone exhibits moderate anticancer activity against human cancer cell lines (SK-MEL, KB, BT-549 and SK-OV-3) with IC50 values of 5.5 and 10.5 μg/mL. Pendulone also shows moderate cytotoxicities against monkey kidney fibroblasts (VERO) and pig kidney epithelial cells (LLC-PK11)[2].
Pendulone shows strong inhibition on the effect of the cell cycle induced by 12-O-tetradecanoyl-phorbol-13-acetate (TPA) in Raji cells[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Pendulone shows potent anti-tumor-promoting activity for an in vivo two-stage carcinogenesis test of mouse skin using 7,12-dimethylbenz[a]-anthracene and TPA[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

316.31

Formula

C17H16O6

CAS 号

69359-09-7

中文名称

垂崖豆藤异黄烷醌

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Qingxi Su, et al. Antiplasmodial Isoflavanes and Pterocarpans from Apoplanesia paniculata. Planta Med. 2015 Aug;81(12-13):1128-32.

    [2]. Aziz A Rahman, et al. Antiparasitic and antimicrobial isoflavanquinones from Abrus schimperi. Nat Prod Commun. 2011 Nov;6(11):1645-50.

    [3]. T Konoshima, et al. Anti-tumor promoting activities of isoflavonoids from Wistaria brachybotrys. Biol Pharm Bull. 1997 Aug;20(8):865-8.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Pendulone(Synonyms: 垂崖豆藤异黄烷醌)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Pendulone (Synonyms: 垂崖豆藤异黄烷醌)

Pendulone 是一种异黄烷醌,具有良好的抗疟原虫活性,IC50 为 7.0 µM。Pendulone 还具有抗利什曼原虫、抗菌和抗癌活性。

Pendulone(Synonyms: 垂崖豆藤异黄烷醌)

Pendulone Chemical Structure

CAS No. : 69359-09-7

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Pendulone is a isoflavanquinone with good antiplasmodial activity with an IC50 of 7.0 µM. Pendulone also has antileishmanial, antibacterial and anticancer activity[1][2].

体外研究
(In Vitro)

Pendulone displays moderate antiproliferative activity against the A2780 human ovarian cancer cell line, with an IC50 value 19.6 µM[1].
Pendulone displays an IC50 value of 0.43 µg/mL, against L. donovani promastigotes. Pendulone also displays antibacterial activity against Staphylococcus aureus and methicillin-resistant S. aureus (each IC50 of 1.44 µg/mL)[2].
Pendulone exhibits moderate anticancer activity against human cancer cell lines (SK-MEL, KB, BT-549 and SK-OV-3) with IC50 values of 5.5 and 10.5 μg/mL. Pendulone also shows moderate cytotoxicities against monkey kidney fibroblasts (VERO) and pig kidney epithelial cells (LLC-PK11)[2].
Pendulone shows strong inhibition on the effect of the cell cycle induced by 12-O-tetradecanoyl-phorbol-13-acetate (TPA) in Raji cells[3].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Pendulone shows potent anti-tumor-promoting activity for an in vivo two-stage carcinogenesis test of mouse skin using 7,12-dimethylbenz[a]-anthracene and TPA[3].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

316.31

Formula

C17H16O6

CAS 号

69359-09-7

中文名称

垂崖豆藤异黄烷醌

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Qingxi Su, et al. Antiplasmodial Isoflavanes and Pterocarpans from Apoplanesia paniculata. Planta Med. 2015 Aug;81(12-13):1128-32.

    [2]. Aziz A Rahman, et al. Antiparasitic and antimicrobial isoflavanquinones from Abrus schimperi. Nat Prod Commun. 2011 Nov;6(11):1645-50.

    [3]. T Konoshima, et al. Anti-tumor promoting activities of isoflavonoids from Wistaria brachybotrys. Biol Pharm Bull. 1997 Aug;20(8):865-8.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务