L-threo-PPMP

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

L-threo-PPMP 

L-threo-PPMP 是一种 GlcT (UDP-Glc: Ceramide β1,1glucosyltransferase) 抑制剂。L-threo-PPMP 抑制鞘糖脂生物合成并诱导细胞凋亡。L-threo-PPMP 具有抗癌活性。

L-threo-PPMP

L-threo-PPMP Chemical Structure

CAS No. : 207278-87-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

L-threo-PPMP is a GlcT (UDP-Glc: Ceramide β1,1glucosyltransferase) inhibitor. L-threo-PPMP inhibits glycosphingolipid biosynthesis and induces apoptosis. L-threo-PPMP has anti-cancer activity[1].

体外研究
(In Vitro)

L-threo-PPMP (0.5-20 μM) induces apoptosis in carcinoma (Colo-205; SKBR3) cells after 6 h and damaging DNA between 24 and 48 h after treatment[1].
L-threo-PPMP (1-16 μM; 48 hours) includes Caspase-3 activation in breast cancer SKBR3 cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

474.72

Formula

C29H50N2O3

CAS 号

207278-87-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Subhash Basu, et al. Apoptosis of human carcinoma cells in the presence of inhibitors of glycosphingolipid biosynthesis: I. Treatment of Colo-205 and SKBR3 cells with isomers of PDMP and PPMP. Glycoconj J. 2004;20(3):157-68.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

L-threo-PPMP

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

L-threo-PPMP 

L-threo-PPMP 是一种 GlcT (UDP-Glc: Ceramide β1,1glucosyltransferase) 抑制剂。L-threo-PPMP 抑制鞘糖脂生物合成并诱导细胞凋亡。L-threo-PPMP 具有抗癌活性。

L-threo-PPMP

L-threo-PPMP Chemical Structure

CAS No. : 207278-87-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

L-threo-PPMP is a GlcT (UDP-Glc: Ceramide β1,1glucosyltransferase) inhibitor. L-threo-PPMP inhibits glycosphingolipid biosynthesis and induces apoptosis. L-threo-PPMP has anti-cancer activity[1].

体外研究
(In Vitro)

L-threo-PPMP (0.5-20 μM) induces apoptosis in carcinoma (Colo-205; SKBR3) cells after 6 h and damaging DNA between 24 and 48 h after treatment[1].
L-threo-PPMP (1-16 μM; 48 hours) includes Caspase-3 activation in breast cancer SKBR3 cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

474.72

Formula

C29H50N2O3

CAS 号

207278-87-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Subhash Basu, et al. Apoptosis of human carcinoma cells in the presence of inhibitors of glycosphingolipid biosynthesis: I. Treatment of Colo-205 and SKBR3 cells with isomers of PDMP and PPMP. Glycoconj J. 2004;20(3):157-68.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

L-threo-PPMP

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

L-threo-PPMP 

L-threo-PPMP 是一种 GlcT (UDP-Glc: Ceramide β1,1glucosyltransferase) 抑制剂。L-threo-PPMP 抑制鞘糖脂生物合成并诱导细胞凋亡。L-threo-PPMP 具有抗癌活性。

L-threo-PPMP

L-threo-PPMP Chemical Structure

CAS No. : 207278-87-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

L-threo-PPMP is a GlcT (UDP-Glc: Ceramide β1,1glucosyltransferase) inhibitor. L-threo-PPMP inhibits glycosphingolipid biosynthesis and induces apoptosis. L-threo-PPMP has anti-cancer activity[1].

体外研究
(In Vitro)

L-threo-PPMP (0.5-20 μM) induces apoptosis in carcinoma (Colo-205; SKBR3) cells after 6 h and damaging DNA between 24 and 48 h after treatment[1].
L-threo-PPMP (1-16 μM; 48 hours) includes Caspase-3 activation in breast cancer SKBR3 cells[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

474.72

Formula

C29H50N2O3

CAS 号

207278-87-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Subhash Basu, et al. Apoptosis of human carcinoma cells in the presence of inhibitors of glycosphingolipid biosynthesis: I. Treatment of Colo-205 and SKBR3 cells with isomers of PDMP and PPMP. Glycoconj J. 2004;20(3):157-68.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

L-threo Lysosphingomyelin (d18:1)(Synonyms: L-threo-Sphingosylphosphorylcholine)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

L-threo Lysosphingomyelin (d18:1) (Synonyms: L-threo-Sphingosylphosphorylcholine)

L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) 是一种内源性生物活性鞘脂。L-threo Lysosphingomyelin (d18:1) 是一种有效的 S1P 受体激动剂,对于hS1P1、hS1P3、hS1P2EC50 分别为 19.3、131.8 和 313.3 nM。

L-threo Lysosphingomyelin (d18:1)(Synonyms: L-threo-Sphingosylphosphorylcholine)

L-threo Lysosphingomyelin (d18:1) Chemical Structure

CAS No. : 105615-55-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) is an endogenous bioactive sphingolipid. L-threo Lysosphingomyelin (d18:1) is a potent S1P receptor agonist with EC50s of 19.3, 131.8, and 313.3 nM for hS1P1, hS1P3, and hS1P2, respectively[1].

IC50 & Target[1]

S1PR1

19.3 nM (EC50, human)

S1PR3

131.8 nM (EC50, human)

S1PR2

313.3 nM (EC50, human)

分子量

464.62

Formula

C23H49N2O5P

CAS 号

105615-55-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Im DS, et al. Characterization of the human and mouse sphingosine 1-phosphate receptor, S1P5 (Edg-8): structure-activity relationship of sphingosine1-phosphate receptors. Biochemistry. 2001;40(46):14053-14060.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

L-threo Lysosphingomyelin (d18:1)(Synonyms: L-threo-Sphingosylphosphorylcholine)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

L-threo Lysosphingomyelin (d18:1) (Synonyms: L-threo-Sphingosylphosphorylcholine)

L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) 是一种内源性生物活性鞘脂。L-threo Lysosphingomyelin (d18:1) 是一种有效的 S1P 受体激动剂,对于hS1P1、hS1P3、hS1P2EC50 分别为 19.3、131.8 和 313.3 nM。

L-threo Lysosphingomyelin (d18:1)(Synonyms: L-threo-Sphingosylphosphorylcholine)

L-threo Lysosphingomyelin (d18:1) Chemical Structure

CAS No. : 105615-55-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) is an endogenous bioactive sphingolipid. L-threo Lysosphingomyelin (d18:1) is a potent S1P receptor agonist with EC50s of 19.3, 131.8, and 313.3 nM for hS1P1, hS1P3, and hS1P2, respectively[1].

IC50 & Target[1]

S1PR1

19.3 nM (EC50, human)

S1PR3

131.8 nM (EC50, human)

S1PR2

313.3 nM (EC50, human)

分子量

464.62

Formula

C23H49N2O5P

CAS 号

105615-55-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Im DS, et al. Characterization of the human and mouse sphingosine 1-phosphate receptor, S1P5 (Edg-8): structure-activity relationship of sphingosine1-phosphate receptors. Biochemistry. 2001;40(46):14053-14060.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

L-threo Lysosphingomyelin (d18:1)(Synonyms: L-threo-Sphingosylphosphorylcholine)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

L-threo Lysosphingomyelin (d18:1) (Synonyms: L-threo-Sphingosylphosphorylcholine)

L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) 是一种内源性生物活性鞘脂。L-threo Lysosphingomyelin (d18:1) 是一种有效的 S1P 受体激动剂,对于hS1P1、hS1P3、hS1P2EC50 分别为 19.3、131.8 和 313.3 nM。

L-threo Lysosphingomyelin (d18:1)(Synonyms: L-threo-Sphingosylphosphorylcholine)

L-threo Lysosphingomyelin (d18:1) Chemical Structure

CAS No. : 105615-55-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) is an endogenous bioactive sphingolipid. L-threo Lysosphingomyelin (d18:1) is a potent S1P receptor agonist with EC50s of 19.3, 131.8, and 313.3 nM for hS1P1, hS1P3, and hS1P2, respectively[1].

IC50 & Target[1]

S1PR1

19.3 nM (EC50, human)

S1PR3

131.8 nM (EC50, human)

S1PR2

313.3 nM (EC50, human)

分子量

464.62

Formula

C23H49N2O5P

CAS 号

105615-55-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Im DS, et al. Characterization of the human and mouse sphingosine 1-phosphate receptor, S1P5 (Edg-8): structure-activity relationship of sphingosine1-phosphate receptors. Biochemistry. 2001;40(46):14053-14060.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

threo-Guaiacylglycerol β-coniferyl ether

threo-Guaiacylglycerol β-coniferyl ether

  【编号】:SPR00931

  【产品名称】:threo-Guaiacylglycerol β-coniferyl ether

  【规格】:10mg

  【用途】:

  threo-Guaiacylglycerol β-coniferyl ether对照品

  编号:SPR00931
  英文名称:threo-Guaiacylglycerol β-coniferyl ether
  CAS No.:869799-76-8
  分 子 式:C20H24O7
  分 子 量:376.405
  类别:上海金畔生物科技有限公司,天然提取物
  作为标准品,对照品或者供研究用,不能直接用于人体。

threo-1-(4-Hydroxy-3-methoxyphenyl)propane-1,2-diol

threo-1-(4-Hydroxy-3-methoxyphenyl)propane-1,2-diol

  【编号】:SPR02857

  【产品名称】:threo-1-(4-Hydroxy-3-methoxyphenyl)propane-1,2-diol

  【规格】:10mg

  【用途】:

  threo-1-(4-Hydroxy-3-methoxyphenyl)propane-1,2-diol对照品

  编号:SPR02857
  英文名称:threo-1-(4-Hydroxy-3-methoxyphenyl)propane-1,2-diol
  CAS No.:848031-94-7
  分 子 式:C10H14O4
  分 子 量:198.218
  类别:上海金畔生物科技有限公司,天然提取物
  作为标准品,对照品或者供研究用,不能直接用于人体。