标签归档：tyr

多肽定制Cyclo(-Gly-Tyr(PO3H2)-Val-Pro-Met-Leu) 编码 [158778-21-3]

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名称 Cyclo(-Gly-Tyr(PO3H2)-Val-Pro-Met-Leu)
编码 [158778-21-3]
别名 Cyclo(-Gly-Tyr(PO3H2)-Val-Pro-Met-Leu)
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） Cyclo(-G-Tyr(PO3H2)-VPM-Leu)
序列（三字母缩写） Cyclo(-Gly-Tyr(PO3H2)-Val-Pro-Met-Leu)
基本描述
溶解度
分子量 0
化学式
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents Cyclo(-Gly-Tyr(PO3H2)-Val-Pro-Met-Leu) 编码 [158778-21-3]
Figures Cyclo(-Gly-Tyr(PO3H2)-Val-Pro-Met-Leu) 编码 [158778-21-3]
Reference
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化学桥

多肽定制DOTA-(Tyr3)-Octreotate 编码 [177943-89-4]

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名称 DOTA-(Tyr3)-Octreotate
编码 [177943-89-4]
别名 DOTA-(Tyr3)-Octreotate
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） DOTA-fCYwKTCT (Cys & Cys bridge)
序列（三字母缩写） 4,7,10-Tricarboxymethyl-1,4,7,10-tetraaza-cyclododecan-1-yl-acetyl-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr-OH (acetate salt)(Disulfide bond)
基本描述 A group of compounds comprising DOTA, a metal chelator that carries a radionuclide and octreotide (an octapeptide that is a potent somatostatin (SST)) analog (where DOTA is tetra-aza-cyclododecane-N N’N”N-“‘-tetra-acetate).
溶解度
分子量 1435.65
化学式 C65H90N14O19S2
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents DOTA-(Tyr3)-Octreotate 编码 [177943-89-4]
Figures DOTA-(Tyr3)-Octreotate 编码 [177943-89-4]
Reference W.A.Breeman et al., Eur. J. Nucl. Med. Mol. Imaging, 30, 917 (2003) A.Capello et al., Cancer Biother. Radiopharm., 18, 761 (2003) M.de Jong et al., J. Nucl. Med., 46, 13S (2005) L.Kolby et al., Br. J. Cancer, 93, 1144 (2005) R.Valkema et al., J. Nucl. Med., 46, 83S (2005)
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化学桥 (Disulfide bond)

多肽定制DOTA-[Tyr3]-Octreotide 编码 [177943-89-4]

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名称 DOTA-[Tyr3]-Octreotide
编码 [177943-89-4]
别名 DOTA-[Tyr3]-Octreotide
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） DOTA-fCYwKTCT-ol (C2&C7 bridge)
序列（三字母缩写） DOTA-DPhe-Cys-Tyr-DTrp-Lys-Thr-Cys-Thr-ol (trifluoroacetate salt)(Cys2 and 7 bridge)
基本描述 This NYAD-2 peptide is NYAD-1 labeled with FITC (Ex/Em=493/517 nm). NYAD-1 is a cell-penetrating alphalpha-Helical peptide used as a potential HIV-1 inhibitor. The hydrocarbon-stapled structure enhances alpha helicity.
溶解度
分子量 1421.64
化学式 C65H90N14O19S2
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents DOTA-[Tyr3]-Octreotide 编码 [177943-89-4]
Figures DOTA-[Tyr3]-Octreotide 编码 [177943-89-4]
Reference L.Kolby et al., Br. J. Cancer, 93, 1144 (2005) R.Valkema et al., J. Nucl. Med., 46, 83S (2005) M.de Jong et al., J. Nucl. Med., 46, 13S (2005) W.A.Breeman et al., Eur. J. Nucl. Med. Mol. Imaging, 30, 917 (2003) A.Capello et al., Cancer Biother. Radiopharm., 18, 761 (2003) Chinol, M. et al. Semin. Nucl. Med. 32,141(2002) De Jong, M. et al. semin Nucl. Med. 32,133(2002)
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化学桥 (Cys2 and 7 bridge)

多肽定制For-Met-Leu-Tyr-OH 编码

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名称 For-Met-Leu-Tyr-OH
编码
别名 For-Met-Leu-Tyr-OH
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） For-MLY-OH
序列（三字母缩写） For-Met-Leu-Tyr
基本描述
溶解度
分子量 0
化学式
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents For-Met-Leu-Tyr-OH 编码
Figures For-Met-Leu-Tyr-OH 编码
Reference
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化学桥

多肽定制H-Arg-Gly-Tyr-Ala-Leu-Gly-OH 编码 [59587-24-5]

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名称 H-Arg-Gly-Tyr-Ala-Leu-Gly-OH
编码 [59587-24-5]
别名 H-Arg-Gly-Tyr-Ala-Leu-Gly-OH
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） RGYALG-OH
序列（三字母缩写） Arg-Gly-Tyr-Ala-Leu-Gly
基本描述
溶解度
分子量 0
化学式
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents H-Arg-Gly-Tyr-Ala-Leu-Gly-OH 编码 [59587-24-5]
Figures H-Arg-Gly-Tyr-Ala-Leu-Gly-OH 编码 [59587-24-5]
Reference
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化学桥

多肽定制H-Glu-Pro-Gln-Tyr(PO3H2)-Glu-Glu-Ile-Pro-Ile-Tyr-Leu-OH 编码

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名称 H-Glu-Pro-Gln-Tyr(PO3H2)-Glu-Glu-Ile-Pro-Ile-Tyr-Leu-OH
编码
别名 H-Glu-Pro-Gln-Tyr(PO3H2)-Glu-Glu-Ile-Pro-Ile-Tyr-Leu-OH
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） EPQ-Tyr(PO3H2)-EEIPIYL-OH
序列（三字母缩写） Glu-Pro-Gln-Tyr(PO3H2)-Glu-Glu-Ile-Pro-Ile-Tyr-Leu
基本描述
溶解度
分子量 0
化学式
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents H-Glu-Pro-Gln-Tyr(PO3H2)-Glu-Glu-Ile-Pro-Ile-Tyr-Leu-OH 编码
Figures H-Glu-Pro-Gln-Tyr(PO3H2)-Glu-Glu-Ile-Pro-Ile-Tyr-Leu-OH 编码
Reference
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化学桥

多肽定制H-Lys-Phe-Tyr-OH 编码 [63958-93-0]

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名称 H-Lys-Phe-Tyr-OH
编码 [63958-93-0]
别名 H-Lys-Phe-Tyr-OH
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） KFY-OH
序列（三字母缩写） Lys-Phe-Tyr
基本描述
溶解度
分子量 0
化学式
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents H-Lys-Phe-Tyr-OH 编码 [63958-93-0]
Figures H-Lys-Phe-Tyr-OH 编码 [63958-93-0]
Reference
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化学桥

多肽定制H-Phe-Tyr-OH 编码 [17355-18-9]

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名称 H-Phe-Tyr-OH
编码 [17355-18-9]
别名 H-Phe-Tyr-OH
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） FY-OH
序列（三字母缩写） Phe-Tyr
基本描述
溶解度
分子量 0
化学式
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents H-Phe-Tyr-OH 编码 [17355-18-9]
Figures H-Phe-Tyr-OH 编码 [17355-18-9]
Reference
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化学桥

多肽定制H-Tyr-Cys-Phe-Ala-Trp-Lys-Thr-Phe-Cys-OH 编码 [647016-22-6]

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名称 H-Tyr-Cys-Phe-Ala-Trp-Lys-Thr-Phe-Cys-OH
编码 [647016-22-6]
别名 H-Tyr-Cys-Phe-Ala-Trp-Lys-Thr-Phe-Cys-OH
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） YCFAWKTFC-OH
序列（三字母缩写） Tyr-Cys-Phe-Ala-Trp-Lys-Thr-Phe-Cys
基本描述
溶解度
分子量 0
化学式
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents H-Tyr-Cys-Phe-Ala-Trp-Lys-Thr-Phe-Cys-OH 编码 [647016-22-6]
Figures H-Tyr-Cys-Phe-Ala-Trp-Lys-Thr-Phe-Cys-OH 编码 [647016-22-6]
Reference
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N端
化学桥

多肽定制H-Tyr-Phe-Met-Arg-Phe-NH2 编码 [99414-63-8]

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名称 H-Tyr-Phe-Met-Arg-Phe-NH2
编码 [99414-63-8]
别名 H-Tyr-Phe-Met-Arg-Phe-NH2
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） YFMRF-NH2
序列（三字母缩写） Tyr-Phe-Met-Arg-Phe-NH2
基本描述
溶解度
分子量 0
化学式
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents H-Tyr-Phe-Met-Arg-Phe-NH2 编码 [99414-63-8]
Figures H-Tyr-Phe-Met-Arg-Phe-NH2 编码 [99414-63-8]
Reference
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N端
化学桥

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH 

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) 是一种高亲和力的五肽，与 src SH2 域结合 (IC50≈1 µM)。Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH 是 src SH3-SH2：磷酸蛋白相互作用的抑制剂。

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH Chemical Structure

CAS No. : 159439-02-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH is an inhibitor for src SH3-SH2:phosphoprotein interactions[1].

分子量

803.70

Formula

C32H46N5O17P
CAS 号

159439-02-8
Sequence Shortening

Ac–{Tyr(PO3H2)}-EEIE-OH
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. G J Pacofsky, et al. Potent dipeptide inhibitors of the pp60c-src SH2 domain. J Med Chem. 1998 May 21;41(11):1894-908.

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Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA 

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) 是一种高亲和力的五肽，与 src SH2 域结合 (IC50≈1 µM)。Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA 是 src SH3-SH2：磷酸蛋白相互作用的抑制剂。

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA is an inhibitor for src SH3-SH2:phosphoprotein interactions[1].

分子量

917.73

Formula

C34H47F3N5O19P
Sequence Shortening

Ac–{Tyr(PO3H2)}-EEIE-OH
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. G J Pacofsky, et al. Potent dipeptide inhibitors of the pp60c-src SH2 domain. J Med Chem. 1998 May 21;41(11):1894-908.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH 

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) 是一种高亲和力的五肽，与 src SH2 域结合 (IC50≈1 µM)。Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH 是 src SH3-SH2：磷酸蛋白相互作用的抑制剂。

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH Chemical Structure

CAS No. : 159439-02-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH is an inhibitor for src SH3-SH2:phosphoprotein interactions[1].

分子量

803.70

Formula

C32H46N5O17P
CAS 号

159439-02-8
Sequence Shortening

Ac–{Tyr(PO3H2)}-EEIE-OH
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. G J Pacofsky, et al. Potent dipeptide inhibitors of the pp60c-src SH2 domain. J Med Chem. 1998 May 21;41(11):1894-908.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH 

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) 是一种高亲和力的五肽，与 src SH2 域结合 (IC50≈1 µM)。Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH 是 src SH3-SH2：磷酸蛋白相互作用的抑制剂。

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH Chemical Structure

CAS No. : 159439-02-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH is an inhibitor for src SH3-SH2:phosphoprotein interactions[1].

分子量

803.70

Formula

C32H46N5O17P
CAS 号

159439-02-8
Sequence Shortening

Ac–{Tyr(PO3H2)}-EEIE-OH
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. G J Pacofsky, et al. Potent dipeptide inhibitors of the pp60c-src SH2 domain. J Med Chem. 1998 May 21;41(11):1894-908.

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Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA 

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) 是一种高亲和力的五肽，与 src SH2 域结合 (IC50≈1 µM)。Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA 是 src SH3-SH2：磷酸蛋白相互作用的抑制剂。

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA is an inhibitor for src SH3-SH2:phosphoprotein interactions[1].

分子量

917.73

Formula

C34H47F3N5O19P
Sequence Shortening

Ac–{Tyr(PO3H2)}-EEIE-OH
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. G J Pacofsky, et al. Potent dipeptide inhibitors of the pp60c-src SH2 domain. J Med Chem. 1998 May 21;41(11):1894-908.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA 

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) 是一种高亲和力的五肽，与 src SH2 域结合 (IC50≈1 µM)。Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA 是 src SH3-SH2：磷酸蛋白相互作用的抑制剂。

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA is an inhibitor for src SH3-SH2:phosphoprotein interactions[1].

分子量

917.73

Formula

C34H47F3N5O19P
Sequence Shortening

Ac–{Tyr(PO3H2)}-EEIE-OH
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. G J Pacofsky, et al. Potent dipeptide inhibitors of the pp60c-src SH2 domain. J Med Chem. 1998 May 21;41(11):1894-908.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

多肽定制Lys-(Tyr8)-Bradykinin 编码

发表于由

上海金畔生物科技有限公司可以定制不同序列多肽，可以访问官网了解更多产品信息。

名称 Lys-(Tyr8)-Bradykinin
编码
别名 Lys-(Tyr8)-Bradykinin
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） KRPPGFSPYR-OH
序列（三字母缩写） Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Tyr-Arg
基本描述
溶解度
分子量 0
化学式
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents Lys-(Tyr8)-Bradykinin 编码
Figures Lys-(Tyr8)-Bradykinin 编码
Reference
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多肽定制Lys-[Tyr8]-Bradykinin 编码

发表于由

上海金畔生物科技有限公司可以定制不同序列多肽，可以访问官网了解更多产品信息。

名称 Lys-[Tyr8]-Bradykinin
编码
别名 Lys-[Tyr8]-Bradykinin
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） KRPPGFSPYR
序列（三字母缩写） Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Tyr-Arg
基本描述
溶解度
分子量 1204.41
化学式 C56H85N17O13
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents Lys-[Tyr8]-Bradykinin 编码
Figures Lys-[Tyr8]-Bradykinin 编码
Reference
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N端
化学桥

多肽定制Suc-Tyr-Val-Ala-Asp-AMC 编码 [201860-29-9]

发表于由

上海金畔生物科技有限公司可以定制不同序列多肽，可以访问官网了解更多产品信息。

名称 Suc-Tyr-Val-Ala-Asp-AMC
编码 [201860-29-9]
别名 Suc-Tyr-Val-Ala-Asp-AMC
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） Suc-YVAD-AMC
序列（三字母缩写） Suc-Tyr-Val-Ala-Asp-AMC
基本描述 Chromogenic caspase-1 substrate.
溶解度
分子量 723.7
化学式 C35H41N5O12
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents Suc-Tyr-Val-Ala-Asp-AMC 编码 [201860-29-9]
Figures Suc-Tyr-Val-Ala-Asp-AMC 编码 [201860-29-9]
Reference
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N端
化学桥

多肽定制Suc-Tyr-Val-Ala-Asp-pNA 编码 [208264-84-0]

发表于由

上海金畔生物科技有限公司可以定制不同序列多肽，可以访问官网了解更多产品信息。

名称 Suc-Tyr-Val-Ala-Asp-pNA
编码 [208264-84-0]
别名 Suc-Tyr-Val-Ala-Asp-pNA
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） Suc-YVAD-pNA
序列（三字母缩写） Suc-Tyr-Val-Ala-Asp-pNA
基本描述
溶解度
分子量 686.7
化学式 C31H38N6O12
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents Suc-Tyr-Val-Ala-Asp-pNA 编码 [208264-84-0]
Figures Suc-Tyr-Val-Ala-Asp-pNA 编码 [208264-84-0]
Reference
C端
N端
化学桥