Mogroside VI 是一种三萜糖苷,是一种非糖类甜味剂。Mogroside 比蔗糖更甜。Mogroside 具有抗氧化,抗糖尿病和抗癌活性。
Mogroside VI Chemical Structure
CAS No. : 189307-15-1
规格
是否有货
5 mg
询价
10 mg
询价
25 mg
询价
* Please select Quantity before adding items.
生物活性
Mogroside VI is a triterpenoid glycoside and a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities[1].
分子量
1449.58
Formula
C66H112O34
CAS 号
189307-15-1
中文名称
罗汉果苷 VI;罗汉果甜苷 VI;罗汉果甙 VI;罗汉果甜甙 VI
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Itkin M, et al. The biosynthetic pathway of the nonsugar, high-intensity sweetener mogroside V from Siraitia grosvenorii.Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7619-E7628.
Mogroside VI 是一种三萜糖苷,是一种非糖类甜味剂。Mogroside 比蔗糖更甜。Mogroside 具有抗氧化,抗糖尿病和抗癌活性。
Mogroside VI Chemical Structure
CAS No. : 189307-15-1
规格
是否有货
5 mg
询价
10 mg
询价
25 mg
询价
* Please select Quantity before adding items.
生物活性
Mogroside VI is a triterpenoid glycoside and a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities[1].
分子量
1449.58
Formula
C66H112O34
CAS 号
189307-15-1
中文名称
罗汉果苷 VI;罗汉果甜苷 VI;罗汉果甙 VI;罗汉果甜甙 VI
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Itkin M, et al. The biosynthetic pathway of the nonsugar, high-intensity sweetener mogroside V from Siraitia grosvenorii.Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7619-E7628.
Mogroside VI 是一种三萜糖苷,是一种非糖类甜味剂。Mogroside 比蔗糖更甜。Mogroside 具有抗氧化,抗糖尿病和抗癌活性。
Mogroside VI Chemical Structure
CAS No. : 189307-15-1
规格
是否有货
5 mg
询价
10 mg
询价
25 mg
询价
* Please select Quantity before adding items.
生物活性
Mogroside VI is a triterpenoid glycoside and a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities[1].
分子量
1449.58
Formula
C66H112O34
CAS 号
189307-15-1
中文名称
罗汉果苷 VI;罗汉果甜苷 VI;罗汉果甙 VI;罗汉果甜甙 VI
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Itkin M, et al. The biosynthetic pathway of the nonsugar, high-intensity sweetener mogroside V from Siraitia grosvenorii.Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7619-E7628.
Polyphyllin VI,一种活性皂甙,具有抗癌活性。Polyphyllin VI 诱导 G2/M 细胞周期停滞并引发细胞凋亡。Polyphyllin VI 通过诱导非小细胞肺癌中的 ROS/NF-κB/NLRP3/GSDMD 信号轴来诱导 caspase-1 介导的细胞焦亡 (pyroptosis)。
Polyphyllin VI Chemical Structure
CAS No. : 55916-51-3
规格
价格
是否有货
数量
5 mg
¥1580
In-stock
10 mg
¥2690
In-stock
20 mg
¥4570
In-stock
50 mg
询价
100 mg
询价
* Please select Quantity before adding items.
Polyphyllin VI 相关产品
•相关化合物库:
Natural Product Library Plus
Bioactive Compound Library Plus
Apoptosis Compound Library
Immunology/Inflammation Compound Library
NF-κB Signaling Compound Library
Natural Product Library
Anti-Cancer Compound Library
Glycoside Compound Library
Lipid Compound Library
Anti-Lung Cancer Compound Library
生物活性
Polyphyllin VI, an active saponin, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis[1][2]. Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis in non-small cell lung cancer[3].
分子量
738.90
Formula
C39H62O13
CAS 号
55916-51-3
中文名称
重楼皂苷VI
运输条件
Room temperature in continental US; may vary elsewhere.
[1]. Lin Z, et al. Anti-lung Cancer Effects of Polyphyllin VI and VII Potentially Correlate with Apoptosis In Vitro and In Vivo. Phytother Res. 2015 Oct;29(10):1568-76.
[2]. Liu Y, et al. Molecular Mechanisms of Apoptosis in HepaRG Cell Line Induced by Polyphyllin VI via the Fas Death Pathway and Mitochondrial-Dependent Pathway. Toxins (Basel). 2018 May 15;10(5). pii: E201.
[3]. Jin-Feng Teng, et al. Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer. Cancers (Basel). 2020 Jan 13;12(1):193.
VI 16832 是一种广谱的 I 型激酶抑制剂,可用作不同癌细胞系中蛋白激酶比较表达分析的富集工具。
VI 16832 Chemical Structure
CAS No. : 1430218-51-1
规格
价格
是否有货
数量
10 mM * 1 mL in DMSO
¥2842
In-stock
1 mg
¥1100
In-stock
5 mg
¥3300
In-stock
10 mg
¥5000
In-stock
50 mg
¥15000
In-stock
100 mg
¥21000
In-stock
200 mg
询价
500 mg
询价
* Please select Quantity before adding items.
VI 16832 相关产品
•相关化合物库:
Bioactive Compound Library Plus
Kinase Inhibitor Library
Anti-Cancer Compound Library
生物活性
VI 16832 is a broad spectrum Type I kinase inhibitor which can be used as an enrichment tool for the comparative expression analysis of protein kinases in different cancer cell lines.
IC50 & Target
Type I kinase[1]
体外研究 (In Vitro)
VI 16832 is a broad spectrum Type I kinase inhibitor[1]. Phosphoproteomics analysis of VI 16832-enriched fractions from MV4-11, HCT116, or 435S cells results in more than 8500 phosphopeptide identifications. These translate into almost 1700 distinct phosphopeptide species derived from 212 different members of the protein kinase superfamily. Analysis of VI 16832-retained proteins from the three cancer cell lines considerably increases the overall number of identified phosphorylation sites on protein kinases. Considering the sum of all phosphopeptide intensities as a measure for VI 16832-enriched protein amount, more than 80% is derived from protein kinases[2].
上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量
391.47
Formula
C22H25N5O2
CAS 号
1430218-51-1
运输条件
Room temperature in continental US; may vary elsewhere.
[1]. Kyla. A. L. Collins, et al. Proteomic Analysis Defines Kinase Taxonomies Specific for Subtypes of Breast Cancer. Apr. 1, 2017.
[2]. Felix S. Oppermann, et al. Large-scale Proteomics Analysis of the Human Kinome. Mol Cell Proteomics. 2009 Jul; 8(7): 1751-1764.
Kinase Assay [2]
Cells are lysed in a volume of 35 to 40 mL per experiment. The protein amounts of the starting extracts used in the first and second experiments are: 435S, 85 and 120 mg; HCT116, 240 and 175 mg; MV4-11, 180 and 120 mg. Lysates are adjusted to 1 M NaCl prior to loading onto the VI 16832 column at a flow rate of 0.07 mL/min. Subsequent washing and elution steps are performed. Protein-containing elution fractions are lyophilized, resuspended in one tenth of the initial volume, and then desalted by protein precipitation prior to gel electrophoresis[2].
上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献
[1]. Kyla. A. L. Collins, et al. Proteomic Analysis Defines Kinase Taxonomies Specific for Subtypes of Breast Cancer. Apr. 1, 2017.
[2]. Felix S. Oppermann, et al. Large-scale Proteomics Analysis of the Human Kinome. Mol Cell Proteomics. 2009 Jul; 8(7): 1751-1764.