RTIL 13

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

RTIL 13 

RTIL 13 是一种有效的动力蛋白 GTPase 抑制剂，抑制动力蛋白 I GTPase 的 IC50 值为 2.3 µM。RTIL 13 还靶向 pleckstrin 同源脂质结合域。RTIL 13 可以抑制受体介导和突触囊泡内吞作用，IC50 分别为 9.3 μM 和 7.1 μM。

RTIL 13

RTIL 13 Chemical Structure

CAS No. : 1009376-10-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

RTIL 13 is a potent inhibitor of dynamin GTPase, with an IC50 of 2.3 µM for dynamin I GTPase. RTIL 13 also targets pleckstrin homology lipid binding domain. RTIL 13 can inhibit receptor-mediated and synaptic vesicle endocytosis, with IC50s of 9.3 μM and 7.1 μM, respectively[1][2].

IC50 & Target

IC50: 2.3 µM (dynamin I GTPase)[1]
体外研究
(In Vitro)

RTIL 13 inhibits receptor-mediated and synaptic vesicle endocytosis, with IC50s of 9.3 μM and 7.1 μM, respectively[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

571.67

Formula

C30H55BrN2O3
CAS 号

1009376-10-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhang J, et, al. From Spanish fly to room-temperature ionic liquids (RTILs): synthesis, thermal stability and inhibition of dynamin 1 GTPase by a novel class of RTILs. New Journal of Chemistry. 2008 Jan; 32(1): 1-180.

    [2]. Ascent Scientific Launch Novel Dynamin Inhibitor Dyngo-4a™ with Children’s Medical Research Institute and University of Newcastle. Tuesday, December 28, 2021.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务