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名称 | Thyrotropin Releasing Hormone, TRH (Human) |
编码 | [24305-27-9] |
别名 | Thyrotropin Releasing Hormone, TRH (Human) |
纯度 | 80%,90%,95%,98%,99% |
重量 | 1mg,5mg,10mg,50mg,100mg,1g |
序列(单字母缩写) | Pyr-HP-NH2 |
序列(三字母缩写) | Pyr-His-Pro-NH2 |
基本描述 | Peptide that binds with high affinity to CRF receptor types 1, 2a & 2b, stimulates cAMP accumulation from cells transfected with those receptors, and acts in vitro to releaes ACTH from dispersed rat anterior pituitary cells. In using a genomic library, the human urocortin has been cloned and localized to human chromosome 2. It has also been discovered that both human and rat urocortin share 95% identity within the mature peptide region. |
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分子量 | 362.4 |
化学式 | C16H22N6O4 |
存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
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Reference | Ohki, K. et al. Chem. Pharm. Bull. 45, 194 (1997) Laakkonen, L. et al. Mol. Pharmacol. 49, 1092 (1996) Scanes, C. et al. Acta Endocrinol. (Copenh) 97, 448 (1981). |
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