多肽定制Neuropeptide W-23 (human) 编码 [383415-79-0]

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名称 Neuropeptide W-23 (human)
编码 [383415-79-0]
别名 Neuropeptide W-23 (human)
纯度 80%,90%,95%,98%,99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列(单字母缩写) WYKHVASPRYHTVGRAAGLLMGL
序列(三字母缩写) H-Trp-Tyr-Lys-His-Val-Ala-Ser-Pro-Arg-Tyr-His-Thr-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Met-Gly-Leu-OH (trifluoroacetate salt)
基本描述 This peptide was recently identified as the endogenous ligand for the two structurally related orphan G-protein-coupled receptors (GPCRs) GPR7 and GPR8 which are expressed in the central nervous system. NPW-30 activated and bound to both GPR7 and GPR8 at similar effective doses. Intracerebroventricular administration of NPW in rats resulted in an increased food intake and stimulation of prolactin release indicating that NPW acts as a mediator of the central control of feeding and the neuroendocrine system.
溶解度
分子量 2584.05
化学式 C119H183N35O28S1
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents Neuropeptide W-23 (human)          编码     [383415-79-0]
Figures Neuropeptide W-23 (human)          编码     [383415-79-0]
Reference Shimomura et al., J. Biol. Chem., 277, 35826 (2002) S.Brezillon et al., J. Biol. Chem., 278, 776 (2003) H.Tanaka et al., Proc. Natl. Acad. Sci. USA, 100, 6251 (2003) M.S.Mondal et al., Endocrinology, 144, 4729 (2003)
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