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名称	KR-12 (human)
编码	[1218951-51-9]
别名	KR-12 (human)
纯度	80%，90%，95%，98%，99%
重量	1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写）	KRIVQRIKDFLR-NH2
序列（三字母缩写）	H-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-NH2?(trifluoroacetate salt)
基本描述	LL-37 is an antimicrobial peptide with angiogenic activity. It corresponds to the C-terminal sequence (134-170) of the human cathelicidin antimicrobial protein hCAP18/LL-37 and is extracellularly released from hCAP18/LL-37 by proteolytic processing. hCAP18/LL-37 is an effector of the innate immune system and is expressed in leukocytes and epithelial cells where it is upregulated in association with inflammation and injury. An overexpression of hCAP18/LL-37 in a series of breast carcinomas could be demonstated. LL-37 has been suggested to stimulate epithelial cell proliferation partially through formyl peptide receptor-like 1 (FPRL1) since blocking the receptor with pertussis toxin decreased the proliferative effect of LL-37 by approximately 50 %.
溶解度
分子量	1570.95
化学式	C71H127N25O15
存储条件	Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Reference	G.Wang, J. Biol. Chem., 283, 32637 (2008)
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