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| 名称 | [Lys(Me1)373]-p53 (368-393), p53 K373(Me1), biotin-labeled, human |
| 编码 | |
| 别名 | [Lys(Me1)373]-p53 (368-393), p53 K373(Me1), biotin-labeled, human |
| 纯度 | 80%，90%，95%，98%，99% |
| 重量 | 1mg,5mg,10mg,50mg,100mg,1g |
| 序列（单字母缩写） | Biotin-KGWHLKS-K(Me1)-KGQSTSRHKKLMFKTEGPDSD-NH2 |
| 序列（三字母缩写） | Biotin-Lys-Gly-Trp-His-Leu-Lys-Ser-Lys(Me1)-Lys-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2(trifluoroacetate salt) |
| 基本描述 | This peptide is derived from amino acid residues 377-387 of human p53 tumor suppressor protein, with monomethylation at Lys382. Methylation of p53 at Lys382 inhibits expression of p53 target genes and decreases apoptotic and cell cycle arrest functions of p53. This allows p53-dependent DNA repair without apoptosis. Levels of this peptide decrease in response to DNA damage |
| 溶解度 | |
| 分子量 | 3582.2 |
| 化学式 | |
| 存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
| 注释 | |
| Documents | ![[Lys(Me1)373]-p53 (368-393), p53 K373(Me1), biotin-labeled, human 编码](http://www.fluoroprobe.com/wp-content/uploads/2022/10/20221013_634891c526353.png) |
| Figures | ![[Lys(Me1)373]-p53 (368-393), p53 K373(Me1), biotin-labeled, human 编码](http://www.fluoroprobe.com/wp-content/uploads/2022/10/20221013_634891c582532.jpg) |
| Reference | Krishnan, S. et al. ChemBioChem 12, 254 (2011) Huang, J. et al. J Biol Chem 285, 9636 (2010) |
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