多肽定制[Lys(Ac)382]-p53 (372-389), biotin labeled 编码

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名称 [Lys(Ac)382]-p53 (372-389), biotin labeled
编码
别名 [Lys(Ac)382]-p53 (372-389), biotin labeled
纯度 80%,90%,95%,98%,99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列(单字母缩写) Biotin-LC-KKGQSTSRHK-K(Ac)-LMFKTEG-NH2
序列(三字母缩写) Biotin-LC-Lys-Lys-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys(Ac)-Leu-Met-Phe-Lys-Thr-Glu-Gly-NH2?(trifluoroacetate salt)
基本描述 This peptide is a p53 tumor suppressor protein acetylated at lysine 382 upon Ras expression, an event that is essential for its biological function. Acetylation at lysine 382 specifically determines the PAb421 epitope. p53 acts as both a tumor-suppressor and transcription factor that, upon activation by DNA damage and other cellular stress signals, leads to the transcription of genes triggering cell-cycle arrest, apoptosis, and DNA repair
溶解度
分子量 2472
化学式
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents [Lys(Ac)382]-p53 (372-389), biotin labeled          编码
Figures [Lys(Ac)382]-p53 (372-389), biotin labeled          编码
Reference Kubbutat, M. et al. Lett. Nature 387, 299 (1997) Li, M. et al. J. Biol. Chem. 277, 50607 (2002)
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