上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
N3-PEG3-vc-PAB-MMAE 纯度: 98.79%
N3-PEG3-vc-PAB-MMAE 是 drug-linker conjugate for ADC 的一部分，包含抗有丝分裂剂 MMAE (一种 tubulin 抑制剂) 和 3 个单元的 PEG linker。N3-PEG3-vc-PAB-MMAE 具有有效的抗肿瘤活性。
N3-PEG3-vc-PAB-MMAE Chemical Structure
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 1 mg | ￥3500 | In-stock | |
| 5 mg | ￥8500 | In-stock | |
| 10 mg | ￥13500 | In-stock | |
| 50 mg | 询价 | ||
| 100 mg | 询价 |
* Please select Quantity before adding items.
| 生物活性 |
N3-PEG3-vc-PAB-MMAE is a synthesized drug-linker conjugate for ADC that incorporates the MMAE (a tubulin inhibitor ) and 3-unit PEG linker. N3-PEG3-vc-PAB-MMAE shows potent antitumor activity. |
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| IC50 & Target |
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| 体外研究 (In Vitro) |
Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of Dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
1352.66 |
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| Formula |
C67H109N13O16 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
*该产品在溶液状态不稳定，建议您现用现配，即刻使用。 |
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