上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Gimeracil (Synonyms: 吉美嘧啶; Gimestat) 纯度: 99.98%
Gimeracil 是口服氟嘧啶衍生物 S-1 的成分,抑制 DNA DSB 的修复,是 DPYD (二氢嘧啶脱氢酶,DPD) 的有效抑制剂。
Gimeracil Chemical Structure
CAS No. : 103766-25-2
规格 | 价格 | 是否有货 | 数量 |
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Free Sample (0.1-0.5 mg) | Apply now | ||
10 mM * 1 mL in DMSO | ¥605 | In-stock | |
25 mg | ¥550 | In-stock | |
50 mg | ¥770 | In-stock | |
100 mg | ¥990 | In-stock | |
500 mg | ¥1500 | In-stock | |
1 g | 询价 | ||
5 g | 询价 |
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Gimeracil 相关产品
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生物活性 |
Gimeracil, a component of an oral fluoropyrimidine derivative S-1, inhibits DNA DSB repair and is a potent inhibitor of DPYD (dihydropyrimidine dehydrogenase, DPD)[1][2]. |
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体外研究 (In Vitro) |
Gimeracil reduces the frequency of neo-positive clones. Additionally, it sensitized the cells in S-phase more than in G0/G1[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability Assay[1]
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体内研究 (In Vivo) |
Gimeracil (2.5-25 mg/kg, orally) may inhibit the rapid repair of X-ray-induced DNA damage in tumors[3]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
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Clinical Trial |
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分子量 |
145.54 |
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Formula |
C5H4ClNO2 |
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CAS 号 |
103766-25-2 |
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中文名称 |
吉美嘧啶;吉莫斯特 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (687.10 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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