10-Hydroxywarfarin-d5

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10-Hydroxywarfarin-d5 

10-Hydroxywarfarin-d5 是 10-Hydroxywarfarin 氘代物。10-Hydroxywarfarin 是一种血浆代谢物,一种有效的 CYP2C9 抑制剂,IC50 为1.6μM。

10-Hydroxywarfarin-d5

10-Hydroxywarfarin-d5 Chemical Structure

CAS No. : 1286117-65-4

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生物活性

10-Hydroxywarfarin-d5 is a deuterium labeled of 10-Hydroxywarfarin. 10-Hydroxywarfarin ,a plasma metabolite, is a potent CYP2C9 inhibitor with an IC50 of 1.6 μM[1].

分子量

329.36

Formula

C19H11D5O5

CAS 号

1286117-65-4

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Drew R Jones, et al. Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin. Chem Res Toxicol. 2010 May 17;23(5):939-45.

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