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BSJ-03-123 纯度: 99.45%
BSJ-03-123是由Cereblon配体和CDK配体相连的PROTAC,是有效,新颖的CDK6选择性的小分子降解剂。
BSJ-03-123 Chemical Structure
CAS No. : 2361493-16-3
规格 | 价格 | 是否有货 | 数量 |
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Free Sample (0.1-0.5 mg) | Apply now | ||
5 mg | ¥2500 | In-stock | |
10 mg | ¥3500 | In-stock | |
50 mg | ¥7500 | In-stock | |
100 mg | ¥12000 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
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BSJ-03-123 相关产品
•相关化合物库:
- Bioactive Compound Library Plus
生物活性 |
BSJ-03-123 is a PROTAC connected by ligands for Cereblon and CDK as a potent and novel CDK6-selective small-molecule degrader. |
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IC50 & Target |
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体外研究 (In Vitro) |
BSJ-03-123 (BSJ) causes a pronounced anti-proliferative effect in CDK6-dependent AML cell lines by inducing a G1 cell-cycle arrest without a measurable increase in apoptosis[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
937.01 |
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Formula |
C47H56N10O11 |
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CAS 号 |
2361493-16-3 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (106.72 mM; ultrasonic and adjust pH to 3 with HCl) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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