那西肽
基本信息
| 产品名称 | 那西肽 |
|---|---|
| 英文名称 | Nosiheptide |
| 英文别名 | Multhiomycin; Primofax;RP 9671；30,32-Imino-8,5:18,15:40,37-trinitrilo-21,36-([2,4]-endo-thiazolomethanimino)-5H,15H,37H-pyrido[3,2-w][2,11,21,27,31,7,14,17]benzoxatetrathiatriazacyclohexatriacontine nosiheptide deriv.; Multhiomycin; NSC 307240; [11S-[11R* |
| 规格或纯度 | 98% |
| 运输条件 | 超低温冰袋运输 |
一般描述
Nosiheptide是一种由多种放线菌|链霉菌|产生的双环硫肽抗生素。与其他双环硫肽（例如硫链丝菌素）不同，第二个大环环通过相对脆弱的内酯和硫代内酯桥连接到核心环肽上。Nosiheptide具有广谱抗菌活性，并且最近证明与万古霉素相比，在医院和社区获得的MRSA中，抗生素延长了后效。
Product Describtion:
Nosiheptide is a bicyclic thiopeptide antibiotic produced by several species of|actinomycetes|, notably|Streptomyces|. Unlike other bicyclic thiopeptides such as thiostrepton, the second macrocyclic ring is linked by relatively fragile lactone and thiolactone bridges to the core cylic peptide. Nosiheptide has broad spectrum antibacterial activity, and has recently demonstrated a prolonged post-antibiotic effect in both nosocomial and community-acquired MRSA compared with vancomycin.
Product Application：
Nosiheptide is an antibacterial item used in feedstock and feed additives for chickens.
相关属性
| CAS编号 | 56377-79-8 |
|---|---|
| 溶解性 | Soluble in ethanol, methanol, DMF, and DMSO. |
| 储存温度 | -20°C储存 |
| 分子量 | 1222.36 |
| 分子式 | C₅₁H₄₃N₁₃O₁₂S₆ |
| EC号 | 260-138-4 |
| 品牌 | Jinpan |
| Smiles | C/C=C\1/C2=NC(=CS2)C(=O)N[C@@H]3CC(C(=O)OCC4=C5C(=C(C(=O)SC[C@@H](C6=NC(=CS6)C7=N/C(=C\8/NC(=CS8)C(=O)NC(=C)C(=O)N)/C(=O)C=C7C9=NC(=CS9)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)C1=CSC3=N |
| PubChem CID | 25084015 |