4-羟基二癸酸

4-氧代十四烷酸是具有相同链长的肉豆蔻酸酯的类似物，但是掺入了极性氧原子代替亚甲基，导致疏水性降低。4-羟基四氢癸酸抑制HIV复制。充当针对|新隐球菌的杀真菌剂。4-氧杂癸酸可通过抑制N-肉豆蔻酰基转移酶的活性或通过改变已掺入该类似物代替肉豆蔻酸的蛋白质的生理来发挥其作用。

4-Oxatetradecanoic acid is an analog of myristate with same chain length but a polar oxygen atom incorporated in place of a methylene group, resulting in reduced hydrophobicity. 4-Oxatetradecanoic acid inhibits HIV replication. Acts as fungicide against|Cryptococcus neoformans|. 4-Oxatetradecanoic acid may exert its effects by inhibiting the activity of N-myristoyltransferase or by altering the physiology of proteins which have incorporated this analog in place of myristic acid.