潮霉素B
氨基糖苷类抗生素;对原核和真核细胞有活性
粉末,≥60% (HPLC)
有货
基本信息
| 产品名称 | 潮霉素B |
|---|---|
| 英文名称 | Hygromycin B |
| 英文别名 | O-6-Amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1-2-3)-O-β-D-talopyranosyl(1-5)-2-deoxy-N3-methyl-D-streptamine;Hygromycin B |
| 规格或纯度 | 粉末,≥60% (HPLC) |
| 运输条件 | 冰袋运输 |
| 生化机理 | 氨基糖苷类抗生素。对原核和真核细胞均具有活性。通过与30S亚基结合并抑制核糖体易位延伸步骤来抑制蛋白质合成。 |
一般描述
阻止多肽合成和抑制延长。用于原核和真核细胞的选择和保藏。
An antibiotic often used for selection of cells transfected with E. coli hygromycin resistance gene.
Application:
An aminoglycoside antibiotic that kills bacteria by inhibiting protein synthesisHygromycin B is used for the selection and maintenance of prokaryotic and eukaryotic cells that contains the hygromycin resistance gene. This gene is frequently used as a selectable marker in research on plants. It stabilizes the transfer ribonucleic acid (tRNA)-ribosomal acceptor site, thereby inhibiting translocation. In addition to this, it serves as an aminoglycosidic antibiotic which inhibits protein synthesis.
相关属性
| CAS编号 | 31282-04-9 |
|---|---|
| 敏感性 | 对热敏感 |
| 比旋光度 | 20° (C=1,H2O) |
| 熔点 | 160-180°C |
| 溶解性 | Miscible with water, methanol, buffer solution and ethanol. Immiscible with less polar solvents. |
| 储存温度 | 2-8°C储存 |
| MDL号 | MFCD06795479 |
| 密度 | 1.67 |
| 分子量 | 527.52 |
| 分子式 | C20H37N3O13 |
| 品牌 | Jinpan |