硫酸链霉素
基本信息
| 产品名称 | 硫酸链霉素 |
|---|---|
| 英文名称 | Streptomycin sulfate |
| 别名 | 硫酸链霉素;链霉素硫酸盐;链霉素 |
| 英文别名 | Streptomycin sulphate streptomycin, sulfate |
| 规格或纯度 | 720 I.U./mg |
| 运输条件 | 冰袋运输 |
| 生化机理 | Mode of Action: Inhibits prokaryote protein synthesis. Binds to S12 protein of 30S ribosomal subunit, preventing the transition from initiation complex to chain-elongating ribosome, causing miscoding or inhibiting initiation. Mode of Resistance: Mutation in rpsL (gene for S12 ribosomal protein) prevents binding of streptomycin to ribosome. Aminoglycoside phosphotransferase also inactivates. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. |
一般描述
Streptomycin sulfate is an aminocyclitol glycoside antibiotic which interferes with protein synthesis in prokaryotes. This antibiotic is effective against both gram-positive and gram-negative bacteria and is frequently used in cell culture media. Streptomycin inhibits protein synthesis by binding to the 30S ribosomal subunit at the S12 protein thereby inducing a misreading of the genetic code, inhibiting the initiation of translation of DNA which then results in death for a susceptible bacterium.An antibiotic for cell culture.
Streptomycin sulfate is an aminocyclitol glycoside antibiotic which interferes with protein synthesis in prokaryotes. This antibiotic is effective against both gram-positive and gram-negative bacteria and is frequently used in cell culture media. Streptomycin inhibits protein synthesis by binding to the 30S ribosomal subunit at the S12 protein thereby inducing a misreading of the genetic code, inhibiting the initiation of translation of DNA which then results in death for a susceptible bacterium.
An antibiotic for cell culture.
相关属性
| CAS编号 | 3810-74-0 |
|---|---|
| 比旋光度 | -85° (C=1,H2O) |
| 熔点 | 250 °C |
| 溶解性 | Soluble in water (50 mg/ml). |
| 储存温度 | 2-8°C储存 |
| RTECS | WK4990000 |
| MDL号 | MFCD00037023 |
| 密度 | 0.873 |
| 分子量 | 1457.38 |
| 分子式 | C42H84N14O36S3 |
| EC号 | 223-286-0 |
| 品牌 | Jinpan |
| PubChem CID | 19648 |