Cas(7240-37-1), 7-氨基放线菌素D(7-AAD), 7-AAD; 7-AminoActinomycin D,7-Aminoactinomycin D,

发表于由

7-氨基放线菌素D(7-AAD)

Fluorescent DNA dye for apoptosis and flow cytometry studies
≥97.0% (HPLC)

有货

Cas(7240-37-1), 7-氨基放线菌素D(7-AAD), 7-AAD; 7-AminoActinomycin D,7-Aminoactinomycin D,

CAS编号 7240-37-1 | 品牌：Jinpan
7-Aminoactinomycin D

MSDS

质检证书(CoA)

相似产品

  • 分子式 C62H87N13O16
  • 分子量1270.43
  • MDL号 MFCD00077295
  • PubChem编号 65180

货号 (SKU) 包装规格 是否现货 价格 数量
A131295-1mg 1mg 现货 Cas(7240-37-1), 7-氨基放线菌素D(7-AAD), 7-AAD; 7-AminoActinomycin D,7-Aminoactinomycin D,  
A131295-5mg 5mg 现货 Cas(7240-37-1), 7-氨基放线菌素D(7-AAD), 7-AAD; 7-AminoActinomycin D,7-Aminoactinomycin D,  
A131295-25mg 25mg 现货 Cas(7240-37-1), 7-氨基放线菌素D(7-AAD), 7-AAD; 7-AminoActinomycin D,7-Aminoactinomycin D,  

基本信息

产品名称 7-氨基放线菌素D(7-AAD)
英文名称 7-Aminoactinomycin D
别名 7-AAD; 7-AminoActinomycin D
英文别名 7-AAD
应用 A fluorescent DNA dye for apoptosis and flow cytomtery studies.
规格或纯度 ≥97.0% (HPLC)
运输条件 超低温冰袋运输
生化机理 用于细胞凋亡和流式细胞术研究的荧光DNA染料。放线菌素D的鸟嘌呤特异性合成荧光类似物。通过结合到GC区域插入DNA。区分活细胞以及流式细胞仪中的早期和晚期凋亡。

一般描述

7-Aminoactinomycin D ，an analog of the antibiotic actinomycin D ，is a fluorescent DNA dye which is useful for quantifying apoptosis. 7-AAD has also been used in studies on cellular necrosis, chromosome analysis and in cell cycle studies. As a fluorescent DNA dye, 7-AAD is able to intercalate DNA via binding to the GC regions. When used in flow cytometery, 7-AAD can be used to discriminate between live cells as well as early and late apoptosis. Additionally, 7-AAD can also be combined with other staining procedures for analysis of intracellular and cell surface antigens enabling multiparametric analysis. When utilizing 7-AAD with flow cytometery, early and late apoptosis can be studied by varying the concentration of 7-AAD. During apoptosis, the cellular plasma membrane is altered progressively, which allows the cell membrane to become permeable to 7-AAD. 7-AAD staining can also be adapted to include staining with other dyes for intracellular and cell surface antigens. 7-Aminoactinomycin D is an inhibitor of DNA Polymerase and RNA PolymeraseA fluorescent DNA dye for apoptosis and flow cytomtery studies.

7-Aminoactinomycin D ，an analog of the antibiotic actinomycin D ，is a fluorescent DNA dye which is useful for quantifying apoptosis. 7-AAD has also been used in studies on cellular necrosis, chromosome analysis and in cell cycle studies. As a fluorescent DNA dye, 7-AAD is able to intercalate DNA via binding to the GC regions. When used in flow cytometery, 7-AAD can be used to discriminate between live cells as well as early and late apoptosis. Additionally, 7-AAD can also be combined with other staining procedures for analysis of intracellular and cell surface antigens enabling multiparametric analysis. When utilizing 7-AAD with flow cytometery, early and late apoptosis can be studied by varying the concentration of 7-AAD. During apoptosis, the cellular plasma membrane is altered progressively, which allows the cell membrane to become permeable to 7-AAD. 7-AAD staining can also be adapted to include staining with other dyes for intracellular and cell surface antigens. 7-Aminoactinomycin D is an inhibitor of DNA Polymerase and RNA Polymerase
A fluorescent DNA dye for apoptosis and flow cytomtery studies.

相关属性

CAS编号 7240-37-1
敏感性 对光和湿度敏感
熔点 252-253°C
溶解性 Soluble in DMSO (20 mg/ml), ethanol, chloroform (1 mg/ml), and dichloromethane (20 mg/ml).
储存温度 -20°C储存
RTECS AU1579000
MDL号 MFCD00077295
分子量 1270.43
分子式 C62H87N13O16
品牌 Jinpan
备注 如果有可能，您尽量在同一天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
PubChem CID 65180

发表回复