Cas(124436-59-5), Pirodavir, 吡罗达韦,Pirodavir,

吡罗达韦

≥98%

有货

Cas(124436-59-5), Pirodavir, 吡罗达韦,Pirodavir,

CAS编号 124436-59-5 | 品牌:Jinpan
Pirodavir

MSDS

质检证书(CoA)

相似产品

  • 分子式 C21H27N3O3
  • 分子量369.46
  • MDL号 MFCD00866965
  • PubChem编号 71345

货号 (SKU) 包装规格 是否现货 价格 数量
P126501-5mg 5mg 现货 Cas(124436-59-5), Pirodavir, 吡罗达韦,Pirodavir,  
P126501-10mg 10mg 现货 Cas(124436-59-5), Pirodavir, 吡罗达韦,Pirodavir,  
P126501-50mg 50mg 现货 Cas(124436-59-5), Pirodavir, 吡罗达韦,Pirodavir,  

基本信息

产品名称 吡罗达韦
英文名称 Pirodavir
别名 吡罗达韦
英文别名 R-77975;R77975;R 77975;Ethyl 4-[2-[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]benzoate
规格或纯度 ≥98%
运输条件 超低温冰袋运输
生化机理

Description: IC50 Value: Pirodavir inhibits 80 percentage of viruses at 0.064 micrograms/ml(EC80)[2]. pirodavir was one of the most promising capsid-binding compounds to show efficacy in human clinical trials for chemoprophylaxis of the common cold. Susceptibility to hydrolysis precluded its use as an oral agent [1]. in vitro: R-77975's predecessor, R 61837, a substituted phenyl-pyridazinamine, was effective in inhibiting 80% of 100 serotypes tested (EC80) at concentrations above 32 micrograms/ml, pirodavir inhibits the same percentage of viruses at 0.064 micrograms/ml. Pirodavir is also effective in inhibiting 16 enteroviruses, with an EC80 of 1.3 micrograms/ml. Pirodavir acts at an early stage of the viral replication cycle (up to 40 min after infection) and reduces the yield of selected rhinoviruses 1,000- to 100,000-fold in a single round of replication [2]. in vivo: Adults with symptoms of < or = 2 days' duration were randomly assigned to intranasal spr

一般描述

Pirodavir(R 77975)是一类新型广谱抗小核糖核酸病毒化合物的原型,是人鼻病毒HRV外壳结合抑制剂。

Pirodavir (R 77975) is the prototype of a novel class of broad-spectrum antipicornavirus compounds; potent human rhinovirus (HRV) capsid-binding inhibitor.

相关属性

CAS编号 124436-59-5
敏感性 对热敏感
熔点 125 °C
溶解性 25°C: DMSO 67 mg/mL; Water <1 mg/mL; Ethanol 7 mg/mL
储存温度 -20°C储存
MDL号 MFCD00866965
分子量 369.46
分子式 C21H27N3O3
品牌 Jinpan
备注 卖完停产,不再备货
PubChem CID 71345