新生霉素 钠盐
基本信息
| 产品名称 | 新生霉素 钠盐 |
|---|---|
| 英文名称 | Novobiocin sodium salt |
| 规格或纯度 | ≥93% (HPLC) |
| 运输条件 | 冰袋运输 |
| 生化机理 | Novobiocin inhibits DNA synthesis by inhibiting bacterial DNA gyrase targeting the GyrB subunit of the enzyme involved in energy transduction. Novobiocin acts as a competitive inhibitors of the ATPase reaction catalysed by GyrB . It is also a Hsp90 inhibitor . Antimicrobial spectrum: Gram-positive bacterial. Mode of Action: Inhibits DNA synthesis by inhibiting the enzyme Topoisomerase II. Antimicrobial spectrum: Gram-positive bacterial. |
一般描述
General Description
Chemical structure: coumarin-glycoside
Application
Novobiocin is used to study heat shock protein inhibition and to produce positively supercoiled plasmid DNA. It is an inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. It also is an inhibitor of retrovirus RNA-dependent DNA-polymerase. For the production of positively supercoiled plasmid DNA. Inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. Inhibitor of retrovirus RNA-dependent DNA-polymerase.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Store under inert gas. Keep in a dry place.
General Description
Chemical structure: coumarin-glycoside
Application
Novobiocin is used to study heat shock protein inhibition and to produce positively supercoiled plasmid DNA. It is an inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. It also is an inhibitor of retrovirus RNA-dependent DNA-polymerase. For the production of positively supercoiled plasmid DNA. Inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. Inhibitor of retrovirus RNA-dependent DNA-polymerase.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Store under inert gas. Keep in a dry place.
相关属性
| CAS编号 | 1476-53-5 |
|---|---|
| 熔点 | 215°C |
| 溶解性 | H2O：可溶 |
| 储存温度 | 2-8°C储存 |
| RTECS | RD5425000 |
| 分子量 | 634.61 |
| 分子式 | C31H35N2NaO11 |
| EC号 | 216-023-6 |
| 品牌 | Jinpan |
| PubChem CID | 54730021 |